scholarly journals Research on the relationship between reduced scattering coefficient and intracranial pressure in brain edema model

2021 ◽  
Author(s):  
Shaobo Wang ◽  
Yangyang Liu ◽  
Yubing Liu ◽  
Zhiyu Qian ◽  
Zaoqin Chen
Keyword(s):  
Intracranial Pressure ◽  
Brain Edema ◽  
Near Infrared ◽  
Scattering Coefficient ◽  
Nondestructive Monitoring ◽  
Neurosurgical Patients ◽  
Infrared Technology ◽  
Parameter Measuring ◽  
The Mathematical Model ◽  
Reduced Scattering Coefficient

Intracranial hypertension is a serious threat to the health of neurosurgical patients. At present, there is a lack of a safe and effective technology to monitor intracranial pressure (ICP) accurately and nondestructively. In this paper, based on near infrared technology, the continuous nondestructive monitoring of ICP change caused by brain edema was studied. The rat brain edema models were constructed by lipopolysaccharide. The ICP monitor and the self-made near infrared tissue parameter measuring instrument were used to monitor the invasive intracranial pressure and the reduced scattering coefficient of brain tissue during the brain edema development. The results showed that there was a negative correlation between the reduced scattering coefficient (690[Formula: see text]nm and 834[Formula: see text]nm) and ICP, and then the mathematical model was established. The experimental results promoted the development of nondestructive ICP monitoring based on near infrared technology.

A Portable Multi-Wavelength near Infrared Photon Time-of-flight Instrument for Measuring Light Scattering

2009 ◽  
Vol 17 (4) ◽  
pp. 167-176
Author(s):  
Francis W.L. Esmonde-White ◽  
David H. Burns
Keyword(s):  
Light Scattering ◽  
Infrared Spectra ◽  
Near Infrared ◽  
Optical Scattering ◽  
Dual Wavelength ◽  
Scattering Coefficient ◽  
Scattering Coefficients ◽  
Near Infrared Spectra ◽  
New Instrument ◽  
Reduced Scattering Coefficient

Measured light scattering properties can be used to improve quantitative spectroscopic analyses of turbid samples. Instruments currently used to measure scattering coefficients are not optimised for portability. A hand-held, dual-wavelength instrument was developed and validated for rapid measurement of reduced scattering coefficients in tandem with near infrared spectra. Tissue simulating phantoms composed of Intralipid and dye were used to model clinically relevant optical properties. Time-dependent intensity profiles of diffusely reflected near infrared pulsed laser light were collected from phantoms and processed to estimate scattering coefficients. In turbid solutions, optical scattering was measured at 850 nm and 905 nm with coefficients of variation of 14.1% and 11.6% over a clinically-relevant reduced scattering coefficient range of 1 mm−1 to 6 mm−1. This dual-wavelength scattering measurement provides a practical method for measuring optical scattering. A 35% precision improvement in quantification of an absorbing dye is shown by incorporating the measured reduced scattering coefficients when processing NIR spectra. We discuss the new instrument, methods for estimating the scattering coefficient from the measured temporal profiles and, finally, how the reduced scattering coefficient is used to correct NIR measurements. Correction of near infrared spectra using optical scattering measurements offers one direction for improving practical non-invasive biomedical quantification techniques.

Investigation on Local Optical Parameters of Liver Tumors in Laser-Induced Thermotherapy

2011 ◽  
Vol 121-126 ◽  
pp. 3998-4002 ◽  
Author(s):  
Li Juan Dai ◽  
Guo Ran Hua ◽  
Ai Ping Qian ◽  
Zhi Yu Qian
Keyword(s):  
Near Infrared ◽  
Liver Tumors ◽  
Stable State ◽  
Heating Time ◽  
Scattering Coefficient ◽  
Tissue Temperature ◽  
Optical Parameters ◽  
Functional Near Infrared Spectroscopy ◽  
Reduced Scattering Coefficient

The method to investigation the changes of optical properties and evaluating the effect of laser application in real time is presented in this paper. In vivo measurements of the reduced scattering coefficient (μ’s) and tissue temperature (T) were performed with a functional near infrared spectroscopy (fNIRS) system and a temperature measurement system during LITT. Mice liver tumors were examined in vivo in different laser doses (0.8W, 1.0W, 1.2W, 1.4W) at a certain heating time (600s). The results showed that there were the same rising tendencies of the reduced scattering coefficient and temperature during LITT. They increased quickly at the beginning, gradually reached a stable state, and rose faster when the laser power was greater. When the tissue temperature was in the range of 50°C to 70°C, there was a clear linear relationship between μ’s and T. The linear equation was obtained for the first time.

scholarly journals Possible correlation between blood glucose concentration and the reduced scattering coefficient of tissues in the near infrared

1994 ◽  
Vol 19 (24) ◽  
pp. 2062 ◽  
Author(s):  
John S. Maier ◽  
Scott A. Walker ◽  
Sergio Fantini ◽  
Maria Angela Franceschini ◽  
Enrico Gratton
Keyword(s):  
Blood Glucose ◽  
Glucose Concentration ◽  
Near Infrared ◽  
Blood Glucose Concentration ◽  
Scattering Coefficient ◽  
Reduced Scattering Coefficient

Indocyanine green near infrared technology in demarcating midplane during pure laparoscopic donor hepatectomy: Useful but not necessary.

2021 ◽  
Author(s):  
Vishal Chorasiya ◽  
Qaleem Mohammed ◽  
Kausar Makki ◽  
Arif Ali khan ◽  
Furquan Ahmed ◽  
...  
Keyword(s):  
Indocyanine Green ◽  
Near Infrared ◽  
Donor Hepatectomy ◽  
Infrared Technology
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