scholarly journals Hardware and system architecture for a very large database

Author(s):  
Robert Healey ◽  
Bradford Heckman
2014 ◽  
Vol 63 (12) ◽  
pp. A1458
Author(s):  
Parag Joshi ◽  
Seth Martin ◽  
Michael Blaha ◽  
John McEvoy ◽  
Raul Santos ◽  
...  

2014 ◽  
Vol 63 (12) ◽  
pp. A1459
Author(s):  
Kristopher Swiger ◽  
Seth Martin ◽  
Michael Blaha ◽  
Peter Toth ◽  
Khurram Nasir ◽  
...  

2020 ◽  
Vol 16 (6) ◽  
pp. 1279-1287 ◽  
Author(s):  
Vasanth Sathiyakumar ◽  
Vincent A. Pallazola ◽  
Jihwan Park ◽  
Rachit M. Vakil ◽  
Peter Toth ◽  
...  

Author(s):  
Kristopher J. Swiger ◽  
Seth S. Martin ◽  
Michael J. Blaha ◽  
Peter P. Toth ◽  
Khurram Nasir ◽  
...  

2016 ◽  
Vol 67 (13) ◽  
pp. 1908
Author(s):  
Kamil F. Faridi ◽  
Joshua Lupton ◽  
Seth Martin ◽  
Krishnaji Kulkarni ◽  
Steven Jones ◽  
...  

2016 ◽  
Vol 10 (1) ◽  
pp. 72-81.e1 ◽  
Author(s):  
Joshua R. Lupton ◽  
Kamil F. Faridi ◽  
Seth S. Martin ◽  
Sristi Sharma ◽  
Krishnaji Kulkarni ◽  
...  

1995 ◽  
Vol 03 (03) ◽  
pp. 661-675
Author(s):  
RITA VASCONCELOS

For a long time, it has been widely acknowledged that putting data on a map underlines important features, and helps in the understanding and interpretation of the real world. Recent and extensive developments of spatial statistics and of geostatistics show the growing importance of this field. Our aim was to help physicians to interpret a very large database on heart diseases (acute myocardial infarction and angina pectoris) on the Madeira Islands. Besides standard techniques, such as loglinear models fitting, we decided to explore the spatial aspect of the question, and to bring in to the analysis recent advances in exploratory and robust data analysis. We show the relevance of spatial statistics on the detection of "hidden" variables.


2015 ◽  
Vol 9 (4) ◽  
pp. 511-518.e5 ◽  
Author(s):  
Renato Quispe ◽  
Mohammed Al-Hijji ◽  
Kristopher J. Swiger ◽  
Seth S. Martin ◽  
Mohamed B. Elshazly ◽  
...  

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Abdulhamied Alfaddagh ◽  
Renato Quispe ◽  
Steven R Jones

Background: Dyslipidemia and inflammation independently contribute to atherosclerosis. The associations between different lipid parameters and inflammatory markers is not fully understood. Hypothesis: LDL-C, triglycerides, and HDL-C do not predict inflammation equally. Methods: We analyzed data from 784,233 patients from the second harvest of the Very Large Database of Lipid study with lipids and hsCRP measured. The prevalence of having hsCRP≥2 mg/L was compared in 20 quantiles of non-HDL-C, LDL-C, HDL-C and triglycerides. Using linear regression, we estimated the correlations between hsCRP and lipids and to what degree individual lipid components explain the variation in hsCRP values. We then examined these association by sex and age (≥65 vs <65 years) categories. Results: The median hsCRP of the population was 2.3 mg/L (IQR, 1.0-5.7). The proportion of patients with hsCRP≥2 mg/L progressively increased with higher non-HDL-C, LDL-C, triglycerides quintiles, but decreased with higher HDL-C quintiles. All lipid measures directly correlated with hsCRP value except HDL-C which was inversely correlated (P<0.001 for all). LDL-C and non-HDL-C values explained very little of the variance seen in hsCRP (univariate R 2 = 0.5% and 0.1%, respectively). Triglyceride levels were the strongest predictor of hsCRP (standardized β, 0.21; P<0.001) and explained 4.5% of variability in hsCRP values. HDL-C was the second best (albeit an inverse) predictor of hsCRP (standardized β, -0.19; P<0.001) and explained 3.8% of its variance. Regardless LDL-C quantile, the prevalence of having hsCRP ≥2 mg/L was lower in those also have low triglyceride or high HDL-C levels (Figure). These associations were consistent by sex and age categories. Conclusion: Of major lipid and lipoprotein cholesterol fractions, triglycerides and HDL-C correlated most strongly and non-HDL-C and LDL-C contributed the least to hsCRP.


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