In this chapter, the author will demonstrate and describe a project to develop a unique database with multilingual information and knowledge resource for biomedical dental materials and their properties. The database will be populated with high-quality, peer-reviewed information, equipped with an original search engine which would include all necessary information to (1) do standardization of therapeutic treatments (2) understand, the tissue response to biomaterials; (3) identify biomaterials and tissue matrix environment, to allow deeper understanding of the underlying relationship which allow more effective device design and engineering; (4) develop enabling tools by improvements in high-throughput assay and instrumentation, imaging, modalities, fabrication technologies, computational modelling and bioinformatics;(5) promote scale up, translation and commercialisation.