Wearable and Implantable Sensors for Biomedical Applications

Mobile health technologies offer great promise for reducing healthcare costs and improving patient care. Wearable and implantable technologies are contributing to a transformation in the mobile health era in terms of improving healthcare and health outcomes and providing real-time guidance on improved health management and tracking. In this article, we review the biomedical applications of wearable and implantable medical devices and sensors, ranging from monitoring to prevention of diseases, as well as the materials used in the fabrication of these devices and the standards for wireless medical devices and mobile applications. We conclude by discussing some of the technical challenges in wearable and implantable technology and possible solutions for overcoming these difficulties.

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Innovations in Biomaterials: Achievements and Opportunities

MRS Bulletin ◽

10.1557/mrs2005.147 ◽

2005 ◽

Vol 30 (7) ◽

pp. 540-545 ◽

Cited By ~ 7

Author(s):

Rebecca M. Bergman

Keyword(s):

Medical Devices ◽

Research Society ◽

Controlled Delivery ◽

Enabling Technology ◽

Implantable Medical Devices ◽

Materials Properties ◽

Medical Products ◽

Materials Research ◽

Quality And Reliability ◽

Materials Used

AbstractThis article is an edited transcript based on a presentation given by Rebecca M. Bergman (Medtronic Inc.) as part of Symposium X—Frontiers of Materials Research on November 30, 2004, at the Materials Research Society Fall Meeting in Boston. Materials innovations have been at the heart of many important advances in implantable medical devices. Miniaturization, improved durability and longevity, enhanced biocompatibility, and controlled delivery are several areas where materials innovations have been important in advancing medical products and therapies. The demands on materials used in the physiological environment are stringent and include requirements related to materials properties as well as safety, quality, and reliability. Looking ahead, materials will undoubtedly continue to be an enabling technology for future innovations in medicine, including novel therapies such as tissue engineering, cell therapy, and gene therapy.

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Strength and Phase Identification of Autogenous Laser Brazed Dissimilar Metal Microjoints

Journal of Manufacturing Science and Engineering ◽

10.1115/1.4028778 ◽

2015 ◽

Vol 137 (1) ◽

Cited By ~ 6

Author(s):

Gen Satoh ◽

Caian Qiu ◽

Syed Naveed ◽

Y. Lawrence Yao

Keyword(s):

Medical Devices ◽

Processing Parameters ◽

Filler Materials ◽

Phase Identification ◽

Implantable Medical Devices ◽

Dissimilar Metal ◽

Brazed Joints ◽

Materials Used ◽

Phase Prediction ◽

Thermal Fluid Flow

The continued advancement of implantable medical devices has resulted in the need to join a variety of dissimilar, biocompatible metal pairs to enable selective use of their unique properties. Typical materials used in implantable medical devices include stainless steel (SS), titanium, platinum (Pt), as well as shape memory materials such as NiTi. Joining these dissimilar metal pairs, however, often results in excessive formation of brittle intermetallics, which significantly reduce the strength of the joints. The use of filler materials to combat the formation of intermetallics, however, results in reduced biocompatibility. Autogenous laser brazing is a novel process that is able to form thin, localized joints between dissimilar metal pairs without filler materials. In this study, the formation of autogenous laser brazed joints between NiTi and SS wires is investigated through experiments and numerical simulations. The strength, composition, microstructure, and phase formation of the resultant joints are investigated as a function of processing parameters and thermal, fluid flow, and phase prediction simulations are used to aid in understanding the joint formation mechanism.

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An Overview of the Use of Equine Collagen as Emerging Material for Biomedical Applications

Journal of Functional Biomaterials ◽

10.3390/jfb11040079 ◽

2020 ◽

Vol 11 (4) ◽

pp. 79

Author(s):

Nunzia Gallo ◽

Maria Lucia Natali ◽

Alessandro Sannino ◽

Luca Salvatore

Keyword(s):

Immune Response ◽

Clinical Trials ◽

Medical Devices ◽

Biomedical Applications ◽

Life Science ◽

Type I Collagen ◽

Experimental Studies ◽

Attractive Alternative ◽

Type I ◽

Implantable Medical Devices

Type I collagen has always aroused great interest in the field of life-science and bioengineering, thanks to its favorable structural properties and bioactivity. For this reason, in the last five decades it has been widely studied and employed as biomaterial for the manufacture of implantable medical devices. Commonly used sources of collagen are represented by bovine and swine but their applications are limited because of the zoonosis transmission risks, the immune response and the religious constrains. Thus, type-I collagen isolated from horse tendon has recently gained increasing interest as an attractive alternative, so that, although bovine and porcine derived collagens still remain the most common ones, more and more companies started to bring to market a various range of equine collagen-based products. In this context, this work aims to overview the properties of equine collagen making it particularly appealing in medicine, cosmetics and pharmaceuticals, as well as its main biomedical applications and the currently approved equine collagen-based medical devices, focusing on experimental studies and clinical trials of the last 15 years. To the best of our knowledge, this is the first review focusing on the use of equine collagen, as well as on equine collagen-based marketed products for healthcare.

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