Exercise Oximetry and Exercise Near-infrared Spectroscopy to Assess Peripheral Artery Disease

Radiographics ◽  
2017 ◽  
Vol 37 (1) ◽  
pp. 363-364
Author(s):  
Vincent Jaquinandi ◽  
Adrien Kaladji ◽  
Alexis Le Faucheur ◽  
Mathieu Léderlin ◽  
Guillaume Mahé
Keyword(s):  
Infrared Spectroscopy ◽  
Peripheral Artery Disease ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Peripheral Artery ◽  
Artery Disease

The use of near-infrared spectroscopy in the diagnosis of peripheral artery disease: A systematic review

Vascular ◽  
2021 ◽  
pp. 170853812110251
Author(s):  
Tomas Baltrūnas ◽  
Valerija Mosenko ◽  
Artūras Mackevičius ◽  
Vilius Dambrauskas ◽  
Ingrida Ašakienė ◽  
...  
Keyword(s):  
Blood Flow ◽  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Tissue Oxygenation ◽  
Arterial Disease ◽  
Diabetic Patients ◽  
Peripheral Artery ◽  
Artery Disease ◽  
Peripheral Arterial

Background Peripheral arterial disease is a stenosis or occlusion of peripheral arteries that results in compromised blood flow and muscle ischemia. The available diagnostic methods are mostly used to measure and visualize blood flow and are not useful in the evaluation of perfusion, especially in diabetic patients, which is now considered to be a research priority by most of the vascular societies around the world as this is still a relatively poorly studied phenomenon. Objective The aim of this review is to explore the clinical significance of muscle tissue oxygenation monitoring in lower-extremity peripheral artery disease diagnosis using the near-infrared spectroscopy method. Methods A systematic search in PubMed, CINAHL, and Cochrane databases was performed to identify clinical near-infrared spectroscopy (NIRS) studies in English and Russian, published until September 2019, involving muscle tissue oxygenation in peripheral arterial disease (PAD). The manuscripts were reviewed by two researchers independently and scored on the quality of the research using MINORS criteria. Results After screening 443 manuscripts, 23 studies ( n = 1580) were included. NIRS-evaluated recovery time seems to be more accurate than ankle-brachial index in diabetic patients to differentiate between moderate and severe claudication. Consistent findings across all the included studies showed that both the oxygenation and deoxygenation rates as well as the recovery times varied from patient to patient and therefore were not suitable for standardization. Conclusions The clinical relevance of routine use of NIRS to diagnose PAD is unproven; therefore, its use is not currently part of standard-of-care for patients with PAD since the absolute values seem to vary significantly, depending on the outside conditions. More data need to be provided on the possible use of NIRS monitoring intraoperatively where the conditions can be more controlled.

scholarly journals Intracoronary near-infrared spectroscopy and the risk of future cardiovascular events

Open Heart ◽  
2019 ◽  
Vol 6 (1) ◽  
pp. e000917 ◽  
Author(s):  
Sofia Karlsson ◽  
Erik Anesäter ◽  
Klara Fransson ◽  
Pontus Andell ◽  
Jonas Persson ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Infrared Spectroscopy ◽  
Coronary Artery ◽  
Near Infrared Spectroscopy ◽  
Cardiovascular Events ◽  
Roc Analysis ◽  
Near Infrared ◽  
Plaque Burden ◽  
Cerebrovascular Events ◽  
Artery Disease

ObjectivesThe objectives of this study were to investigate if findings by intracoronary near-infrared spectroscopy (NIRS) and intravascular ultrasound (IVUS) are associated with future cardiovascular events and if NIRS can differentiate culprit from non-culprit segments in patients with coronary artery disease.MethodsThe study included 144 patients with coronary artery disease undergoing percutaneous coronary intervention and combined NIRS-IVUS imaging at two Swedish hospitals. The NIRS-derived lipid core burden index (LCBI), the 4 mm segment with maximum LCBI (MaxLCBI4mm) and the IVUS-derived maximum plaque burden (MaxPB) were analysed within the culprit segment and continuous 10 mm non-culprit segments of the index culprit vessels. The association with future major adverse cardiovascular and cerebrovascular events (MACCE), defined as all-cause mortality, acute coronary syndrome requiring revascularisation and cerebrovascular events during follow-up was evaluated using multivariable Cox regressions. A receiver operating characteristic (ROC) analysis was performed to test the ability of NIRS to discriminate culprit against non-culprit segments.ResultsA non-culprit maxLCBI4mm ≥400 (HR: 3.67, 95% CI 1.46 to 9.23, p=0.006) and a non-culprit LCBI ≥ median (HR: 3.08, 95% CI 1.11 to 8.56, p=0.031) were both significantly associated with MACCE, whereas a non-culprit MaxPB ≥70% (HR: 0.61, 95% CI 0.08 to 4.59, p=0.63) was not. The culprit segments had larger lipid cores compared with non-culprit segments (MaxLCBI4mm 425 vs 74, p<0.001), and the ROC analysis showed that NIRS can differentiate culprit against non-culprit segments (c-statistics: 0.85, 95% CI 0.81 to 0.89).ConclusionA maxLCBI4mm ≥400 and LCBI ≥ median, assessed by NIRS in non-culprit segments of a culprit artery, were significantly associated with patient-level MACCE. NIRS furthermore adequately discriminated culprit against non-culprit segments in patients with coronary disease.

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