Role of the liver in secretin inactivation

1962 ◽  
Vol 202 (2) ◽  
pp. 347-348 ◽  
Author(s):  
John J. Skillman ◽  
William Silen ◽  
Harold A. Harper
Keyword(s):  
Pancreatic Duct ◽  
Pancreatic Juice ◽  
Main Pancreatic Duct ◽  
Infusion Pump ◽  
Constant Infusion ◽  
Blue Dye ◽  
Total Flow ◽  
Centrifuge Tube ◽  
Portal Veins

In order to determine the effect of the liver on the action of secretin on the pancreas, secretin was infused alternately into the femoral and portal veins of adult mongrel dogs for 15-min periods, using a constant infusion pump. The major pancreatic duct was cannulated transduodenally and pancreatic juice was continuously collected in a graduated centrifuge tube. Injection of Evans blue dye through the main pancreatic duct at the conclusion of each experiment confirmed the ligation of all ducts, other than the major one, so that collections represented total flow of pancreatic juice. In each pair of infusions (portal and systemic) the volume of pancreatic juice obtained was always greater when secretin was given by the systemic route, and this increase in volume was highly significant statistically ( P < .005). These observations indicate that the effect of secretin on the pancreas is partially inactivated by the liver.

scholarly journals ON THE COLLECTION OF THE ENTIRE EXTERNAL SECRETION OF THE PANCREAS UNDER STERILE CONDITIONS AND THE FATAL EFFECT OF TOTAL LOSS OF PANCREATIC JUICE

1927 ◽  
Vol 45 (3) ◽  
pp. 561-570 ◽  
Author(s):  
Robert Elman ◽  
John M. McCaughan
Keyword(s):  
Pancreatic Duct ◽  
Pancreatic Juice ◽  
Main Pancreatic Duct ◽  
Total Loss ◽  
At Will

It has been possible by appropriate intubation of the main pancreatic duct of the dog to collect the total external secretion of the pancreas under sterile conditions. When all of the secretion is thus collected exitus occurs in a characteristic way in about a week with anorexia, gastric irritability, vomiting and asthenia. The significance of this finding has been briefly discussed. A method is also described for the "altercursive" intubation of the pancreas whereby the secretion may be collected or allowed to flow back to the duodenum at will.

Role of SpyGlass-DS tm in the preoperative assessment of pancreatic intraductal papillary mucinous neoplasm involving the main pancreatic duct

Pancreatology ◽  
2018 ◽  
Vol 18 (5) ◽  
pp. 566-571 ◽  
Author(s):  
Takao Ohtsuka ◽  
Yoshitaka Gotoh ◽  
Yohei Nakashima ◽  
Yoshifumi Okayama ◽  
So Nakamura ◽  
...  
Keyword(s):  
Pancreatic Duct ◽  
Intraductal Papillary Mucinous Neoplasm ◽  
Main Pancreatic Duct ◽  
Preoperative Assessment ◽  
Mucinous Neoplasm ◽  
Spyglass Ds

Retortamonas intestinalis in the pancreatic juice of a patient with small nodular lesions of the main pancreatic duct

2001 ◽  
Vol 53 (4) ◽  
pp. 508-510 ◽  
Author(s):  
Osamu Kawamura ◽  
Youichi Kon ◽  
Atsushi Naganuma ◽  
Taku Iwami ◽  
Hideki Maruyama ◽  
...  
Keyword(s):  
Pancreatic Duct ◽  
Pancreatic Juice ◽  
Main Pancreatic Duct ◽  
Nodular Lesions

scholarly journals The Secretory Flow of Pancreatic Juice in the Main Pancreatic Duct: Visualization by Means of MRCP with Spatially Selective Inversion-Recovery Pulse

Radiology ◽  
2011 ◽  
Vol 261 (2) ◽  
pp. 582-586 ◽  
Author(s):  
Katsuyoshi Ito ◽  
Teruyuki Torigoe ◽  
Tsutomu Tamada ◽  
Koji Yoshida ◽  
Koichi Murakami ◽  
...  
Keyword(s):  
Pancreatic Duct ◽  
Pancreatic Juice ◽  
Main Pancreatic Duct ◽  
Inversion Recovery ◽  
Selective Inversion ◽  
Inversion Recovery Pulse

Role of Peroral Pancreatoscopy (POP) in the Evaluation of Main Pancreatic Duct (MPD) Neoplasia

2009 ◽  
Vol 69 (5) ◽  
pp. AB268 ◽  
Author(s):  
Daniel A. Ringold ◽  
Raj J. Shah ◽  
Roy Yen ◽  
Brian C. Brauer ◽  
Norio Fukami ◽  
...  
Keyword(s):  
Pancreatic Duct ◽  
Main Pancreatic Duct

Postprandial changes in secretory flow of pancreatic juice in the main pancreatic duct: evaluation with cine-dynamic MRCP with a spatially selective inversion-recovery (IR) pulse

2016 ◽  
Vol 26 (12) ◽  
pp. 4339-4344 ◽  
Author(s):  
Kazuya Yasokawa ◽  
Katsuyoshi Ito ◽  
Tsutomu Tamada ◽  
Akira Yamamoto ◽  
Minoru Hayashida ◽  
...  
Keyword(s):  
Pancreatic Duct ◽  
Pancreatic Juice ◽  
Main Pancreatic Duct ◽  
Inversion Recovery ◽  
Selective Inversion

THE ROLE OF ENDOSCOPIC ULTRASOUND IN DIAGNOSIS OF CHRONIC PANCREATITIS

2018 ◽  
pp. 20-26
Author(s):  
Van Huy Tran ◽  
Trung Nam Phan ◽  
Khanh Vinh
Keyword(s):  
Chronic Pancreatitis ◽  
Pancreatic Duct ◽  
Endoscopic Ultrasound ◽  
Main Pancreatic Duct ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Endoscopy Ultrasound ◽  
Pancreatic Duct Stone

Background and aims: To evaluate the efficacy of endoscopic ultrasound for diagnosis chronic pancreatitis by Rosemont classification. Patients and methods: A cross – sectional study was conducted on patients undergoing endoscopy ultrasound to diagnose chronic pancreatitis. Results: Study on a total of 57 patients indicated for endoscopic ultrasound. We have some following results: The lesions of chronic pancreatitis on endoscopic ultrasound: The hyperechoic foci without shadowing and stranding is 82.5% and hyperechoic foci with shadowing is 70.2%, cyst and pseudocyst are about 15.8%. Main pancreatic duct dilation is 71.9%, hyperechoic main pancreatic duct wall is 70.2%, main pancreatic duct stone is about 45.6%. Rosemont classification in diagnosis of chronic pancreatitis: Consistent with chronic pancreatitis by 1 major A feature (+) ≥ 3 minor features is 69.4% and 2 major A features is 30,6%. Suggestive of chronic pancreatitis by over 5 minor features is 100%. EUS is more accurate than CT in detecting early chronic pancreatitis. Conclusions:Endoscopic ultrasound is a highly effective method of diagnosing chronic pancreatitis. Key words: chronic pancreatitis, endoscopic ultrasound

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