THE ROLE OF ENDOSCOPIC ULTRASOUND IN DIAGNOSIS OF CHRONIC PANCREATITIS

2018 ◽  
pp. 20-26
Author(s):  
Van Huy Tran ◽  
Trung Nam Phan ◽  
Khanh Vinh

Background and aims: To evaluate the efficacy of endoscopic ultrasound for diagnosis chronic pancreatitis by Rosemont classification. Patients and methods: A cross – sectional study was conducted on patients undergoing endoscopy ultrasound to diagnose chronic pancreatitis. Results: Study on a total of 57 patients indicated for endoscopic ultrasound. We have some following results: The lesions of chronic pancreatitis on endoscopic ultrasound: The hyperechoic foci without shadowing and stranding is 82.5% and hyperechoic foci with shadowing is 70.2%, cyst and pseudocyst are about 15.8%. Main pancreatic duct dilation is 71.9%, hyperechoic main pancreatic duct wall is 70.2%, main pancreatic duct stone is about 45.6%. Rosemont classification in diagnosis of chronic pancreatitis: Consistent with chronic pancreatitis by 1 major A feature (+) ≥ 3 minor features is 69.4% and 2 major A features is 30,6%. Suggestive of chronic pancreatitis by over 5 minor features is 100%. EUS is more accurate than CT in detecting early chronic pancreatitis. Conclusions:Endoscopic ultrasound is a highly effective method of diagnosing chronic pancreatitis. Key words: chronic pancreatitis, endoscopic ultrasound

2017 ◽  
pp. 40-47
Author(s):  
Khanh Vinh ◽  
Van Huy Tran

Background and aims: To evaluate the efficacy of endoscopy ultrasound for diagnosis chronic pancreatitis by Rosemont classification. Patients and methods: A cross - sectional study was conducted on 44 patients undergoing endoscopy ultrasound to diagnose chronic pancreatitis. Results: Study on a total of 44 patients indicated for endoscopic ultrasound. We have some following results: The lesions of chronic pancreatitis on endoscopic ultrasound: The hyperechoic foci without shadowing and stranding was 79.5% and hyperechoic foci with shadowing was 72.7%, cyst and pseudocyst were about 13.6%. Main pancreatic duct dilation is 75%, hyperechoic main pancreatic duct wall was 72.7%, main pancreatic duct stone and irregular main pancreatic duct contour were about 52.2%. Rosemont classification in diagnosis of chronic pancreatitis: Consistent with chronic pancreatitis by 1 major A feature (+) ≥ 3 minor features is 67.5% and 2 major A features is 32.5%. Suggestive of chronic pancreatitis by over 5 minor features is 100%. EUS is more accurate than CT in detecting early chronic pancreatitis. Conclusions: Endoscopic ultrasound is a highly effective method of diagnosing chronic pancreatitis. Key words: endoscopy ultrasound, chronic pancreatitis


Endoscopy ◽  
2020 ◽  
Author(s):  
Calvin Jianyi Koh ◽  
Sundeep Lakhtakia ◽  
Mitsuhiro Kida ◽  
Cosmas Rinaldi A. Lesmana ◽  
Tiing Leong Ang ◽  
...  

Background Although endoscopic ultrasound (EUS) features and criteria have been described in chronic pancreatitis, challenges remain with interoperator variability and ease of adoption. The aim of this study was to define and validate the EUS features of chronic pancreatitis in a multicenter prospective study in Asia. Method The study was divided into two parts: the first part was conducted to derive the EUS features of chronic pancreatitis with adequate interoperator agreement; the second was to prospectively evaluate these features in a multicenter cross-sectional study and determine the optimal combination of features for the diagnosis of chronic pancreatitis. Prospectively enrolled cases had standard internationally validated radiologic or histologic features of chronic pancreatitis, and controls were patients without chronic pancreatitis who underwent EUS examination. Results The top six EUS features that had good interobserver agreement (mean kappa 0.73, range 0.60 – 0.90) were selected to be further evaluated in part II of the study. These included: hyperechoic foci with shadowing, lobularity with honeycombing, cysts, dilated main pancreatic duct, dilated side branches, and calculi in the main pancreatic duct. A total of 284 subjects (132 cases, 152 controls) were enrolled from 12 centers in Asia. All six features had high accuracy ranging from 63.3 % to 89.1 %. Two or more of these six EUS features accurately defined chronic pancreatitis (sensitivity 94.7 %, specificity 98.0 %), with an area under the receiver operating curve of 0.986. Conclusion This multicenter Asian study characterized and defined the EUS features of chronic pancreatitis. This provides a useful tool in clinical practice and further research in pancreatic cancer surveillance.


2019 ◽  
pp. 17-20
Author(s):  
Van Huy Tran ◽  
Thanh Long Nguyen

Background: Diagnosis of gastrointestinal submucosal tumors (SMT) is still a challenge in clinical practice and data about gastrointestinal submucosal tumors in our country was very limited. This study aimed to assess some characteristics of gastrointestinal submucosal tumors. Patients and Methods: cross–sectional study; 195 patients having gastrointestinal submucosal tumors diagnosed by endoscopic ultrasound at Hue University of Medicine and Pharmacy Hospital were enrolled from October 2013 to December 2018. Cutting biopsy or EUS- FNA in case necessary. Results: The mean age of patients was 48.92 ± 15.23. The prevalence was nearly equal in men and women with 48.2% and 51.8%, respectively. According to location, submucosal tumors were 45.6% in the stomach, 35.9% in the esophagus and 2.6% in the colon and rectum. According to etiology, the submucosal cyst was found in 23.6%, the leiomyoma was 22.1%, the Brunner’s gland was 1% and the unknown submucosal tumors was 19.5%. 58.1% of the leiomyoma and 67.4% of the submucosal cyst were found in the esophagus. 76% of the GIST, 83.3% of the ectopic pancreas and 64.7% of the lipoma were found in stomach. Conclusions: Based on endoscopy ultrasound, the most common locations of SMT were stomach and esophagus; the most common SMT were submucosal cyst and leiomyoma. Key words: Submucosal tumor (SMT), Endoscopic ultrasound (EUS)


2019 ◽  
pp. 28-33
Author(s):  
Thi Phuong Nhan Kieu ◽  
Van Huy Tran

Objective: To determine features of endoscopic ultrasound in esophageal cancer and relation with clinic, endoscopy and computerized tomography. Patients and methods: A cross-sectional study was conducted on 40 patients indicated for endoscopic ultrasound to staging esophageal cancer. Results: The total number of patients studied in study were 40. The middle and lower 1/3rd of esophagus affected more commonly compare to other parts. Mean length of tumor in endoscopy was 5.19 ± 2.37cm. The majority of patients presented late with advanced stage of cancer in endoscopy (90%). Squamous cell carcinoma (95%) was the most common histopathological type. CT/TNM staging was documented in 33 (82.5%) patients: T1 (3.1%), T2 (25%), T3 (53.1%), T4a (12.5%), T4b (6.3%), N0 (30.3%). Staging by ultrasonoscopy: Tis (2.5%), T1a (5%), T1b (0), T2 (7.5%), T3 (42.5%), T4a (32.5%), T4b (10%). The predictive value of tumor length was significant in patients with N0 or lympho node status (p = 0.003). Conclusions: Endoscopic ultrasound improved the diagnostic accuracy of esophageal cancer staging. Key words: endoscopic ultrasound, esophageal cance


2020 ◽  
Vol 35 (2) ◽  
pp. 100-104
Author(s):  
Maksudur Rahman ◽  
Mohammad Abdullah Al Mamun ◽  
MAK Azad Chowdhury ◽  
Abu Sayeed Munsi

Background: Recently it has been apprehended that sildenafil, a drug which has been successfully using in the treatment of PPHN and erectile dysfunction in adult, is going to be withdrawn from the market of Bangladesh due to threat of its misuses. Objective: The aim of this study was to see the extent of uses of sildenafil in the treatment of PPHN and importance of availability of this drugs in the market inspite of its probable misuses. Methods: This cross sectional study was conducted in neonatal intensive care unit (NICU), special baby care unit (SCABU) and cardiac intensive care unit (CICU) of Dhaka Shishu (Children) Hospital from June, 2017 to May 2018. Neonates with PPHN were enrolled in the study. All cases were treated with oral sildenefil for PPHN along with others management according to hospital protocol. Data along with other parameters were collected and analyzed. Results: Total 320 patients with suspected PPHN were admitted during the study period. Among them 92 (29%) cases had PPHN. Male were 49(53 %) cases and female were 43(47%) cases. Mean age at hospital admission was 29.7±13.4 hours. Based on echocardiography,13(14%) cases had mild, 38 (41%) cases moderate and 41(45%) cases severe PPHN. Mean duration of sildenafil therapy was 11.9±7.1 days. Improved from PPHN were 83 (90%) cases. Mortality was 10% (9). Conclusion: In this study it was found that the incidence of PPHN is 29% among the suspected newborns. Sildenafil is successfull in improving the oxygenation of PPHN and to decrease the mortality of neonates. DS (Child) H J 2019; 35(2) : 100-104


2012 ◽  
Vol 2 (2) ◽  
pp. 345-350
Author(s):  
Dr. Girish.L Dandagi ◽  
◽  
Venkat kalyana kumar. P ◽  
Dr. Dr.Isaac Mathew ◽  
Dr. Dr.G S Gaude Dr. Dr.G S Gaude

Author(s):  
Serena Barello ◽  
Rosario Caruso ◽  
Lorenzo Palamenghi ◽  
Tiziana Nania ◽  
Federica Dellafiore ◽  
...  

Abstract Purpose The purpose of the present cross-sectional study is to investigate the role of perceived COVID-19-related organizational demands and threats in predicting emotional exhaustion, and the role of organizational support in reducing the negative influence of perceived COVID-19 work-related stressors on burnout. Moreover, the present study aims to add to the understanding of the role of personal resources in the Job Demands-Resources model (JD-R) by examining whether personal resources—such as the professionals’ orientation towards patient engagement—may also strengthen the impact of job resources and mitigate the impact of job demands. Methods This cross-sectional study involved 532 healthcare professionals working during the COVID-19 pandemic in Italy. It adopted the Job-Demands-Resource Model to study the determinants of professional’s burnout. An integrative model describing how increasing job demands experienced by this specific population are related to burnout and in particular to emotional exhaustion symptoms was developed. Results The results of the logistic regression models provided strong support for the proposed model, as both Job Demands and Resources are significant predictors (OR = 2.359 and 0.563 respectively, with p < 0.001). Moreover, healthcare professionals’ orientation towards patient engagement appears as a significant moderator of this relationship, as it reduces Demands’ effect (OR = 1.188) and increases Resources’ effect (OR = 0.501). Conclusions These findings integrate previous findings on the JD-R Model and suggest the relevance of personal resources and of relational factors in affecting professionals’ experience of burnout.


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