scholarly journals Household air pollution: a call for studies into biomarkers of exposure and predictors of respiratory disease

2013 ◽  
Vol 304 (9) ◽  
pp. L571-L578 ◽  
Author(s):  
Jamie Rylance ◽  
Stephen B. Gordon ◽  
Luke P. Naeher ◽  
Archana Patel ◽  
John R. Balmes ◽  
...  

Household air pollution (HAP) from indoor burning of biomass or coal is a leading global cause of morbidity and mortality, mostly due to its association with acute respiratory infection in children and chronic respiratory and cardiovascular diseases in adults. Interventions that have significantly reduced exposure to HAP improve health outcomes and may reduce mortality. However, we lack robust, specific, and field-ready biomarkers to identify populations at greatest risk and to monitor the effectiveness of interventions. New scientific approaches are urgently needed to develop biomarkers of human exposure that accurately reflect exposure or effect. In this Perspective, we describe the global need for such biomarkers, the aims of biomarker development, and the state of development of tests that have the potential for rapid transition from laboratory bench to field use.

2016 ◽  
Vol 97 ◽  
pp. 195-203 ◽  
Author(s):  
Zheng Li ◽  
Adwoa Commodore ◽  
Stella Hartinger ◽  
Michael Lewin ◽  
Andreas Sjödin ◽  
...  

Author(s):  
Busisiwe Shezi ◽  
Caradee Y Wright

One of the greatest threats to public health is personal exposure to air pollution from indoor sources. The impact of air pollution on mortality and morbidity globally and in South Africa is large and places a burden on healthcare systems for treatment and care of air pollution-related diseases. Household air pollution (HAP) exposure attributed to the burning of solid fuels for cooking and heating is associated with several adverse health impacts including impacts on the respiratory system. The researchers sought to update the South African evidence on HAP exposure and respiratory health outcomes from 2005. Our quasi-systematic review produced 27 eligible studies, however, only four of these studies considered measures of both HAP exposure and respiratory health outcomes. While all of the studies that were reviewed show evidence of the serious problem of HAP and possible association with negative health outcomes in South Africa, no studies provided critically important information for South Africa, namely, local estimates of relative risks that may be applied in burden of disease studies and concentration response functions for criteria pollutants. Almost all of the studies that were reviewed were cross-sectional, observational studies. To strengthen the evidence of HAP exposure-health outcome impacts on respiratory health, researchers need to pursue studies such as cohort, time-series and randomised intervention trials, among other study designs. South African and other researchers working in this field need to work together and take a leap towards a new era of epidemiological research that uses more sophisticated methods and analyses to provide the best possible evidence. This evidence may then be used with greater confidence to motivate for policy-making, contribute to international processes such as for guideline development, and ultimately strengthen the evidence for design of interventions that will reduce HAP and the burden of disease associated with exposure to HAP in South Africa.


Author(s):  
Jonathan Thornburg ◽  
Sajia Islam ◽  
Sk Masum Billah ◽  
Brianna Chan ◽  
Michelle McCombs ◽  
...  

The use of liquefied petroleum gas (LPG) for cooking is a strategy to reduce household air pollution (HAP) exposure and improve health. We conducted this feasibility study to evaluate personal exposure measurement methods to representatively assess reductions in HAP exposure. We enrolled 30 pregnant women to wear a MicroPEM for 24 h to assess their HAP exposure when cooking with a traditional stove (baseline) and with an LPG stove (intervention). The women wore the MicroPEM an average of 77% and 69% of the time during the baseline and intervention phases, respectively. Mean gravimetric PM2.5 mass and black carbon concentrations were comparable during baseline and intervention. Temporal analysis of the MicroPEM nephelometer data identified high PM2.5 concentrations in the afternoon, late evening, and overnight during the intervention phase. Likely seasonal sources present during the intervention phase were emissions from brick kiln and rice parboiling facilities, and evening kerosene lamp and mosquito coil use. Mean background adjusted PM2.5 concentrations during cooking were lower during intervention at 71 μg/m3, versus 105 μg/m3 during baseline. Representative real-time personal PM2.5 concentration measurements supplemented with ambient PM2.5 measures and surveys will be a valuable tool to disentangle external sources of PM2.5, other indoor HAP sources, and fuel-sparing behaviors when assessing the HAP reduction due to intervention with LPG stoves.


2020 ◽  
Author(s):  
Joan O’Connell ◽  
Jennifer Rockell ◽  
Margaret Reid ◽  
Kathleen Harty ◽  
Marcelo Perraillon ◽  
...  

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