Magnesium kinetics in adolescent girls determined using stable isotopes: effects of high and low calcium intake

Magnesium kinetics were measured in five adolescent girls who were participating in a calcium balance study. Two calcium levels were fed in a randomized crossover design. After an acclimation period, 26Mg was consumed orally and 25Mg was given intravenously, and then blood, urine, and feces were collected for 14 days. Total magnesium and percent enrichment were determined, and data were fitted to a eight-compartment model. There was no significant difference between high and low calcium intakes for any of the parameters examined. Mean values for control (800 mg/day) and high (1,800 mg/day) calcium intake were as follows: Mg intake, 305 +/- 30 and 286 +/- 9 mg/day; absorption (percent), 44 +/- 7 and 39 +/- 9; absorption (mg/day), 134 +/- 35 and 110 +/- 28; urinary excretion, 96 +/- 22 and 101 +/- 31 mg/day; fecal excretion, 175 +/- 32 and 200 +/- 11 mg/day; and magnesium balance, 13 +/- 35 and -34 +/- 48 mg/day, respectively. In conclusion, high calcium intake did not alter magnesium kinetics or balance in adolescent girls.

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Controlled trial of low calcium versus high calcium intake in mild hypertension

Journal of Hypertension ◽

10.1097/00004872-198803000-00011 ◽

1988 ◽

Vol 6 (3) ◽

pp. 253-256 ◽

Cited By ~ 18

Author(s):

Alfonso Siani ◽

Pasquale Strazzullo ◽

Sergio Guglielmi ◽

Delia Pacioni ◽

Angela Giacco ◽

...

Keyword(s):

Calcium Intake ◽

Mild Hypertension ◽

Controlled Trial ◽

High Calcium Intake ◽

Low Calcium ◽

High Calcium

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Changes in Calcium Kinetics in Adolescent Girls Induced by High Calcium Intake

The Journal of Clinical Endocrinology & Metabolism ◽

10.1210/jc.85.12.4470 ◽

2000 ◽

Vol 85 (12) ◽

pp. 4470-4475 ◽

Cited By ~ 24

Author(s):

M. E. Wastney

Keyword(s):

Adolescent Girls ◽

Calcium Intake ◽

High Calcium Intake ◽

Calcium Kinetics ◽

High Calcium

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Calcium Balance in Osteoporotic Patients on Long-Term Oral Calcium Therapy with and without Sex Hormones

Clinical Science ◽

10.1042/cs0620221 ◽

1982 ◽

Vol 62 (2) ◽

pp. 221-226 ◽

Cited By ~ 4

Author(s):

N. C. Thalassinos ◽

D. H. Gutteridge ◽

G. F. Joplin ◽

T. R. Fraser

Keyword(s):

Calcium Intake ◽

Calcium Absorption ◽

Concomitant Administration ◽

Urinary Calcium ◽

Calcium Balance ◽

Total Calcium ◽

High Calcium Intake ◽

Oral Calcium ◽

High Calcium

1. The effect of a high calcium intake (1 mmol day−1 kg−1) alone or with the concomitant administration of oestradiol and testosterone derivatives was monitored by serial calcium balances in 48 patients with osteoporosis of various types. 2. On high calcium alone there was an increase (P < 0.001) in both total calcium balance and net calcium absorption as compared with values on a simulated home intake. This effect was sustained for periods up to 10 years (mean 3.5 years) by the addition of the hormones. 3. Discontinuation of the hormones (only) produced a significant decrease in both calcium balance and nett absorption but both were still increased when compared with the initial values under simulated home calcium intake. 4. No significant change in the urinary calcium output was observed under any of the regimens.

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Dietary phosphorus intake is positively associated with some radial and tibial pQCT bone traits in premenopausal females with seemingly high calcium intake

Bone Abstracts ◽

10.1530/boneabs.3.pp260 ◽

2014 ◽

Author(s):

Suvi Itkonen ◽

Elisa Saarnio ◽

Virpi Kemi ◽

Heini Karp ◽

Minna Pekkinen ◽

...

Keyword(s):

Calcium Intake ◽

High Calcium Intake ◽

Dietary Phosphorus ◽

High Calcium ◽

Dietary Phosphorus Intake ◽

Phosphorus Intake

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Dietary Calcium Intake and Calcium Supplementation in Hungarian Patients with Osteoporosis

International Journal of Endocrinology ◽

10.1155/2013/754328 ◽

2013 ◽

Vol 2013 ◽

pp. 1-8

Author(s):

Gábor Speer ◽

Pál Szamosujvári ◽

Péter Dombai ◽

Katalin Csóré ◽

Kinga Mikófalvi ◽

...

Keyword(s):

Dietary Intake ◽

Calcium Intake ◽

Calcium Supplementation ◽

Dietary Calcium ◽

Dietary Calcium Intake ◽

Current Recommendation ◽

High Calcium Intake ◽

Osteoporosis Therapy ◽

Average Intake ◽

High Calcium

Purpose. Adequate calcium intake is the basis of osteoporosis therapy—when this proves insufficient, even specific antiosteoporotic agents cannot exert their actions properly.Methods. Our representative survey analyzed the dietary intake and supplementation of calcium in 8033 Hungarian female and male (mean age: 68 years) (68.01 (CI95: 67.81–68.21)) patients with osteoporosis.Results. Mean intake from dietary sources was665±7.9 mg (68.01 (CI95: 67.81–68.21)) daily. A significant positive relationship could be detected between total dietary calcium intake and lumbar spine BMD (P=0.045), whereas such correlation could not be demonstrated with femoralT-score. Milk consumption positively correlated with femur (P=0.041), but not with lumbar BMD. The ingestion of one liter of milk daily increased theT-score by 0.133. Average intake from supplementation was558±6.2 mg (68.01 (CI95: 67.81–68.21)) daily. The cumulative dose of calcium—from both dietary intake and supplementation—was significantly associated with lumbar (r=0.024,P=0.049), but not with femur BMD (r=0.021,P=0.107). The currently recommended 1000–1500 mg total daily calcium intake was achieved in 34.5% of patients only. It was lower than recommended in 47.8% of the cases and substantially higher in 17.7% of subjects.Conclusions. We conclude that calcium intake in Hungarian osteoporotic patients is much lower than the current recommendation, while routinely applied calcium supplementation will result in inappropriately high calcium intake in numerous patients.

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