Single-molecule labeling for studying trafficking of renal transporters
2018 ◽
Vol 315
(5)
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pp. F1243-F1249
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Keyword(s):
The ability to detect and track single molecules presents the advantage of visualizing the complex behavior of transmembrane proteins with a time and space resolution that would otherwise be lost with traditional labeling and biochemical techniques. Development of new imaging probes has provided a robust method to study their trafficking and surface dynamics. This mini-review focuses on the current technology available for single-molecule labeling of transmembrane proteins, their advantages, and limitations. We also discuss the application of these techniques to the study of renal transporter trafficking in light of recent research.
2020 ◽
2009 ◽
Vol 378
(3)
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pp. 376-382
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Keyword(s):
2010 ◽
Vol 43
(8)
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pp. 1135-1143
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Keyword(s):
Keyword(s):