Changes in acid-base balance and blood gases during muscular activity and recovery

1959 ◽  
Vol 14 (3) ◽  
pp. 328-332 ◽  
Author(s):  
R. De Lanne ◽  
J. R. Barnes ◽  
L. Brouha ◽  
F. Massart
Keyword(s):  
Environmental Temperature ◽  
Venous Blood ◽  
Muscular Activity ◽  
Blood Gases ◽  
Blood Oxygen ◽  
Ambient Conditions ◽  
Acid Base Balance ◽  
Acid Base ◽  
Base Balance ◽  
Males And Females

Changes in the blood gases and acid-base balance during muscular work and recovery were investigated for males and females under various controlled environmental conditions. Changes in venous blood oxygen and carbon dioxide are influenced both by the intensity and duration of the exercise and by the environmental temperature. The pH of the blood is similarly affected. The direct measurement of pH was found to be a better index of the variation in the acid-base balance than the pH calculated from Henderson's equation at a fixed CO2 pressure. Lactic acid in the blood is, like the blood gases, influenced by ambient conditions, but is more closely related to the intensity than to the duration of the exercise. Submitted on October 28, 1958

STUDY OF ACID BASE BALANCE IN CHRONIC SEVERE ANAEMIA

2021 ◽  
pp. 48-51
Author(s):  
Balbinder Kumar ◽  
Ganesh Narayan Jha ◽  
Debarshi Jana
Keyword(s):  
Respiratory Infections ◽  
Venous Blood ◽  
Blood Gases ◽  
Severe Anaemia ◽  
Clinical State ◽  
Acid Base Balance ◽  
Acid Base ◽  
Base Parameters ◽  
Base Balance

Aim of the study role of acid base balance in chronic severe anaemic patients admitted in Department of Medicine, Darbhanga Medical College and Hospital, Laheriasarai, Bihar. Study subject include 50 chronic and severe anaemic patients. All the fty cases underwent detailed haematological, biochemical, electrocardiographic, roentgenographic studies followed by extensive analysis of blood for blood gases and acid base parameters at the onset. Some were further studied for venous blood lactate and the effect of intravenous frusemide on the acid base parameters and the clinical state of the patient. Twenty normal controls were also studied. Work in future on the problem of chronic severe anaemia should include cases with cardiac failure and other complications like respiratory infections etc. and they should be studied for myocardial function, glomerular ltration rate and renal anion transport in addition to blood gases and acid base study as done by us. The role of ionotropic agents should be studied in such cases in isolation from that with diuretics. The administration of oxygen alone with a mask is also expected to improve almost all parameters quickly and should be studied.

DIGITALIS TOLERANCE IN YOUNG PUPPIES

PEDIATRICS ◽  
1970 ◽  
Vol 46 (5) ◽  
pp. 730-736
Author(s):  
Katherine H. Halloran ◽  
Steven C. Schimpff ◽  
Jean G. Nicolas ◽  
Norman S. Talner
Keyword(s):  
Blood Gases ◽  
Acid Base Balance ◽  
Acid Base ◽  
Littermate Control ◽  
Premature Ventricular Contractions ◽  
Toxic Dose ◽  
Arterial Blood ◽  
Wide Range ◽  
Base Balance ◽  
The Mean

Tolerance to acetyl strophanthidin, a rapid-acting cardiac aglycone, was determined in 28 anesthetized mongrel puppies, ages 16 to 56 days, and compared to tolerance in 16 littermate puppies in whom acute hypercapnic acidemia was produced. The tolerance was also compared to that of four adult mongrel dogs. The toxic dose was defined as the intravenous amount required to produce four consecutive premature ventricular contractions. A marked variation in the toxic dose was found in the 28 control puppies (range 83 to 353 µg/kg, mean 169 µg/kg) which could not be correlated with age, arterial blood gases or pH, serum potassium or sodium, arterial pressure, or heart rate. The toxic dose was significantly greater in the puppies than in the adult dogs, in whom the mean toxic dose was 64 µg/kg (range 50 to 89 µg/kg). A significant increase in tolerance was also observed in the puppies with hypercapnic acidemia (mean toxic dose 220 µg/kg, range 93 to 375 µg/kg) in comparison to tolerance in the control puppies and despite the wide range of tolerance, each of the puppies with hypercapnic acidemia showed greater tolerance than its littermate control puppy. Assessment of the clinical implications of these findings will require study of the effects of alterations in acid-base balance on the inotropic effect of acetyl strophanthidin in addition to the toxic electrophysiologic effects.

Electrolytes, Blood Gases, and Acid–Base Balance

2017 ◽  
pp. 873-938
Author(s):  
Isabel A. Lea ◽  
Susan J. Borghoff ◽  
Gregory S. Travlos
Keyword(s):  
Blood Gases ◽  
Acid Base Balance ◽  
Acid Base ◽  
Base Balance

scholarly journals Clinical assessment of acid-base balance in Netherland Dwarf rabbit

2020 ◽  
Author(s):  
J. M. Chapel ◽  
J. L. Benedito ◽  
J. Hernández ◽  
P. Famigli-Bergamini ◽  
C. Castillo
Keyword(s):  
Reference Values ◽  
Venous Blood ◽  
Meat Production ◽  
Acid Base Balance ◽  
Acid Base ◽  
Sodium Potassium ◽  
Mean Values ◽  
Base Balance ◽  
Biochemical Profiles ◽  
Made In

Abstract Pet rabbits have increased their popularity in a lot of countries. However, most of the laboratory profiles in rabbit medicine come from the observations made in rabbit as biomodels or meat production. So that further researches are necessary to obtain reference values for hematology and biochemical profiles in pet rabbits and the different breeds, especially, in relation to acid-base balance. The aim of this report was to offer the mean values of the main parameters connected with acid-base profile in Netherland Dwarf breed. Thirty-five healthy rabbits (15 males and 20 females) were studied. Venous blood sample from lateral saphenous vein was analyzed to measure: haematocrit, haemoglobin, blood urea nitrogen, glucose, blood pH, partial pressure of CO2 (pCO2), total CO2, ions bicarbonate, chloride, sodium, potassium, base excess and anion Gap. Results showed a shorter range that those reported by different researchers. Moreover, differences between genders were showed in pCO2, its values were higher in males. It may be associated with a greater cellular metabolism. Values obtained in this research should be taken into account by veterinary clinicians for this breed in their clinical assessments. Besides, these values provide new results in parameters with few reference values.

scholarly journals Effects of a new intravenous electrolyte solution for veterinary therapy on the electrolyte and acid-base balances of healthy horses

2016 ◽  
Vol 46 (8) ◽  
pp. 1479-1485 ◽  
Author(s):  
Priscilla Fajardo Valente Pereira ◽  
José Antonio Bessegatto ◽  
Gabriela de Castro Bregadioli ◽  
Stéfany Lia Oliveira Camilo ◽  
Nathali Adrielli Agassi de Sales ◽  
...  
Keyword(s):  
Electrolyte Solution ◽  
Fluid Therapy ◽  
Repeated Measures ◽  
Venous Blood ◽  
Isotonic Saline ◽  
Acid Base Balance ◽  
Acid Base ◽  
Before And After ◽  
Base Balance ◽  
Clinical Changes

ABSTRACT: The effects of a new intravenous electrolyte solution for veterinary therapy on electrolyte and acid-base balances of horses were evaluated, assessing the potential of the use of this solution as a rational alternative in fluid therapy. Eight healthy adult horses, including 4 males and 4 females, received two treatments in a cross-over design: isotonic saline solution (IS) and a test solution (TS) containing 145mEq of Na+, 5mEq of K+, 4mEq of Ca++, 2mEq of Mg++, 96mEq of Cl-, 60mEq of lactate, 50g of dextrose, and 4mg of cyanocobalamin per liter. Solutions were IV infused in a volume corresponding to 5% of BW, over 3 hours. Venous blood samples were taken 5 times before and after the infusion (at 0, 3, 6, 9 e 24h), for pHv, pCO2v, HCO3 -v, BEv, Na+, K+, Cl-, Ca++, Ca, P, Mg, glucose and L-lactate measurements, and AG and SID calculations. The data were analyzed through repeated measures ANOVA. The IS caused mild acidifying effect by increasing Cl- and decreasing plasma SID. In contrast, the TS induced mild and transient hypochloremia without changes in acid-base balance. Hyperglycemia was present at the end of the TS infusion and reversed 6 hours later. The horses did not exhibit any clinical changes. We concluded that TS is an option for fluid therapy in horses.

Arterial Blood Gases, Acid-Base Balance, and Lactate and Gas Exchange Variables During Hypoxic Exercise

1989 ◽  
Vol 10 (04) ◽  
pp. 279-285 ◽  
Author(s):  
T. Yoshida ◽  
M. Udo ◽  
M. Chida ◽  
K. Makiguchi ◽  
M. Ichioka ◽  
...  
Keyword(s):  
Gas Exchange ◽  
Blood Gases ◽  
Arterial Blood Gases ◽  
Acid Base Balance ◽  
Acid Base ◽  
Arterial Blood ◽  
Base Balance ◽  
Hypoxic Exercise
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