Blood gas tension measurement using a mass spectrometer

1961 ◽  
Vol 16 (3) ◽  
pp. 562-565 ◽  
Author(s):  
L. B. Strang

A bubble equilibration method for the analysis of blood gas tensions is described. A small bubble is equilibrated with blood in a syringe as in the Riley technique and subsequently analyzed in a respiratory mass spectrometer with a modified sampling system. The method is extremely simple and rapid and has an accuracy comparable with the other available techniques. Submitted on January 16, 1961

2018 ◽  
Vol 63 (10) ◽  
pp. 1543-1551
Author(s):  
V. Kogan ◽  
A. S. Antonov ◽  
Yu. V. Chichagov ◽  
O. S. Victorova-Leclerc ◽  
I. V. Victorov ◽  
...  

1982 ◽  
Vol 20 (3) ◽  
pp. 375-382 ◽  
Author(s):  
P. Rolfe ◽  
P. J. Burton ◽  
J. A. Crowe ◽  
I. Basarab-Horwath ◽  
P. J. Goddard ◽  
...  

Author(s):  
Patrick Magee ◽  
Mark Tooley

A blood gas machine has electrodes to measure pH, pCO2 and pO2 and often measures Hb and some biochemistry as well [King et al. 2000]. Derived values from such a device include O2 saturation, O2 content, bicarbonate, base excess and total CO2. This is the Clarke electrode described in the previous section on gas analysers and is suitable for both respiratory and blood O2 analysis. A pH unit has been defined in Chapter 1 as. In words, this can be described as ‘the negative logarithm, to base ten, of the hydrogen ion concentration’. The physical principle on which the pH electrode is based depends on the fact that when a membrane separates two solutions of different [H+], a potential difference exists across the membrane. In a pH electrode, such a membrane is usually made of glass and the development of a potential difference between the two solutions is thought to be due to the migration of H+ into the glass matrix. If one solution consists of a standard [H+], the pH of the other solution can be estimated by measurement of the potential difference between them. The glass membrane used is selectively permeable to H+. No current flows in this device, which does not wear out, in contrast to the Clark electrode, in which current does flow and that does need periodic replacement. The pH measurement system is shown diagrammatically in Figure 17.1. It consists of two half cells. In one half it has an Ag/AgCl electrode and in the other a Hg/HgCl2 (calomel) electrode. Each electrode maintains a fixed electrical potential. The Ag/AgCl electrode is surrounded by a buffer solution of known pH, surrounded by the pH sensitive glass. Outside the glass membrane is the test solution, usually blood, whose pH is to be measured. It is the potential difference across the glass, between these two solutions, which is variable. The blood or other solution is separated from the calomel electrode by a porous plug and a potassium chloride salt bridge to minimise KCl diffusion. The potential difference across the system is about 60 mV per unit of pH change at 37◦C.


2019 ◽  
Vol 489 (4) ◽  
pp. 4734-4740 ◽  
Author(s):  
Isaac R H G Schroeder ◽  
Kathrin Altwegg ◽  
Hans Balsiger ◽  
Jean-Jacques Berthelier ◽  
Michael R Combi ◽  
...  

ABSTRACT The nucleus of the Jupiter-family comet 67P/Churyumov–Gerasimenko was discovered to be bi-lobate in shape when the European Space Agency spacecraft Rosetta first approached it in 2014 July. The bi-lobate structure of the cometary nucleus has led to much discussion regarding the possible manner of its formation and on how the composition of each lobe might compare with that of the other. During its two-year-long mission from 2014 to 2016, Rosetta remained in close proximity to 67P/Churyumov–Gerasimenko, studying its coma and nucleus in situ. Based on lobe-specific measurements of HDO and H2O performed with the ROSINA Double Focusing Mass Spectrometer (DFMS) on board Rosetta, the deuterium-to-hydrogen (D/H) ratios in water from the two lobes can be compared. No appreciable difference was observed, suggesting that both lobes formed in the same region and are homogeneous in their D/H ratios.


2017 ◽  
Vol 15 (9-10) ◽  
pp. 229
Author(s):  
Sutoto Sutoto ◽  
Sunoto Sunoto ◽  
Bambang M. ◽  
Sutejo Sutejo

Blood gas analysis and blood pH examinations have been carried out on 20 children suffering from severe gastroenteritis and dehydration. Ten patients were treated singly with half strength Darrow’s solution in 2.5% glucose containing potassium 17 mEq/L and lactate 26 mEq/ L as base corrector. The other 10 patients were given 3A solution (without potassium), containing lactate as base corrector as much as 53 mEq/L in the first 8 hours, followed by Darrow-Glucose (1:2) solution (with potassium).


Author(s):  
B Kroell ◽  
S Starlinger ◽  
B Eitzinger

AbstractThe objective of this contribution is to characterise the distribution of adhesive between the plug wrap paper and the tipping paper on a finished cigarette. On the one hand, it is well known that this distribution influences various properties of the cigarette, but on the other hand, there are no methods available to completely determine this distribution. The area covered by adhesive, the amount of adhesive, and the thickness and position of the adhesive layer between the plug wrap and the tipping paper were chosen as essential quantities. Image analysis was used to evaluate the area covered by adhesive, and the amount of adhesive between the papers. The thickness and position of the adhesive layer were determined by processing pictures of paper cross-sections obtained with a time-of-flight secondary ion mass spectrometer (TOF-SIMS).


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