Autonomic nervous system and adaptation to cold in man

1975 ◽  
Vol 39 (2) ◽  
pp. 181-186 ◽  
Author(s):  
J. LeBlanc ◽  
S. Dulac ◽  
J. Cote ◽  
B. Girard
Keyword(s):  
Blood Pressure ◽  
Pressor Response ◽  
Cold Pressor ◽  
Pressure Increase ◽  
Quebec City ◽  
Sympathetic Response ◽  
Blood Pressure Increase ◽  
Cold Face ◽  
Cold Face Test ◽  
Made In

The responses to cold hand test (blood pressure increase and tachycardia) and to a cold face test (blood pressure increase and bradycardia) were used to study the role of the autonomic nevrous system in cold adaptation in humans. The Eskimos (men, women, children) were shown to have a very weak sympathetic response to cold but the vagal response (bradycardia) was identical to that of white people. A group of mailmen from Quebec city living outdoors approximately 30 h/wk throughout the year was also studied. A significant decline in the cold pressor response and an enhanced bradycardia (cold face test) were observed at the end of the winter. Similarly the fall in skin temperature of the cheek was not as pronounced when the measurements were made in May compared to those made in October. A group of soldiers was also studied before and after an Arctic expedition. It was found that the bradycardia of the cold face test was also more pronounced after sojourning in the cold. These results indicate that repeated exposures to severe cold in men activate some adaptive mechanisms characterized by a diminution of the sympathetic response and a concomitant enhancement of the vagal activation normally observed when the extremities and the face are exposed to cold.

An Investigation of the Prolonged Pressor Response to Renin in the Nephrectomized Rat

1976 ◽  
Vol 51 (s3) ◽  
pp. 151s-153s ◽  
Author(s):  
G. W. Boyd
Keyword(s):  
Blood Pressure ◽  
Dose Response ◽  
Pressor Response ◽  
Pressure Increase ◽  
Angiotensin I ◽  
Response Curves ◽  
Blood Pressure Increase ◽  
Dose Response Curves

1. In an investigation of the prolonged pressor response to renin that develops after nephrectomy, angiotensin I dose—response curves and rat renin clearances were studied in nephrectomized rats and paired sham-nephrectomized control animals under pentobarbitone anaesthesia. 2. Both threshold and slope of the angiotensin I dose—response curves were decreased at 15–27 h after nephrectomy. 3. The ratio of renin clearance (determined during renin infusions) in the nephrectomized rat to that in the paired sham-nephrectomized control animals was 0·49 ± 0·03 (sem), P < 0·001 (n = 12 pairs). 4. Both factors contribute towards the prolongation of the blood pressure increase after intravenously administered renin in the nephrectomized animal.

Menopause-related blood pressure increase and its relationship to age and body mass index: the SIMONA epidemiological study

2005 ◽  
Vol 23 (12) ◽  
pp. 2269-2276 ◽  
Author(s):  
Alberto Zanchetti ◽  
Rita Facchetti ◽  
Gian Carlo Cesana ◽  
Maria Grazia Modena ◽  
Anna Pirrelli ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Body Mass Index ◽  
Epidemiological Study ◽  
Body Mass ◽  
Pressure Increase ◽  
Blood Pressure Increase

Blood Pressure and Intraventricular Hemorrhage in Premature Infants

PEDIATRICS ◽  
1990 ◽  
Vol 86 (6) ◽  
pp. 1006-1007
Author(s):  
EDWARD H. PERRY ◽  
HENRIETTA S. BADA ◽  
JOHN D. DAY ◽  
SHELDON B. KORONES ◽  
KRISTOPHER L. ARHEART ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Birth Weight ◽  
Premature Infants ◽  
Intraventricular Hemorrhage ◽  
Stability Boundary ◽  
Mean Blood Pressure ◽  
Pressure Increase ◽  
Blood Pressure Increase ◽  
The Mean

In Reply.— We appreciate the interest and comments of Drs Puccio and Soliani regarding our article "Blood Pressure Increase, Birth Weight Dependent Stability Boundary and Intraventricular Hemorrhage."1 In response, we address the following points: 1. Although mean blood pressure (BP) values greater than 100 mm Hg were observed in some of our patients, these were quite rare. The mean BP was found to be less than 60 mm Hg 99% of the time. Thus, unless one is recording BPs through long periods and sampling quite often, the brief spikes likely would not be observed.

scholarly journals The Influence of Noise Intensity and Age to the Employees’ Blood Pressure at Heavy-Duty Shop and EHS Department

2019 ◽  
Vol 8 (2) ◽  
pp. 168
Author(s):  
Achmad Fachrul Megananda ◽  
Tjipto Suwandi
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Noise Intensity ◽  
Health Problems ◽  
Pressure Increase ◽  
P Value ◽  
Heavy Duty ◽  
Blood Pressure Increase ◽  
Influence Of Noise

Introduction: Noise is an unwanted sound heard by the hearers, which can trigger health problems if it continues to be exposed to a certain intensity. One of the health problems that can arise due to noise is the blood pressure increase. This study aims to analyze the influence of noise intensity and age to the blood pressure increase. Methods: This study was an observational study completed with cross-sectional design and analytics. The independent variables in this study were the noise intensity and age, while the dependent variable was the blood pressure. The sample collection of this study applied the total sampling method with 46 employees as respondents, i.e., 29 employees of the heavy-duty shop and 17 employees of the EHS Department in PT. Vale Indonesia. The data analysis was conducted by using the logistic regression statistical test with α-value of 0.05. Results: the noise intensity affected the increase of both systolic blood pressure (significance/p-value=0.00) and diastolic blood pressure (significance/p-value=0.01) with an odds ratio of the increase of systolic blood pressure (Exp (B) =9.75) and the increase of diastolic blood pressure (Exp (B)=5.76). Furthermore, the variable of age does not influence the increase of both systolic (significance/p-value=0.57) and diastolic (significance/p-value=0.41) blood pressures. Conclusion:  the rise of the blood pressure of the employees is affected by the noise intensity factor in the workplace. Keywords: noise intensity, age, blood pressure

scholarly journals SAFETY OF USE OF HIGH ALTITUDE PROTECTION SUITS FOR KINESITHERAPY – PRELIMINARY REPORT

2020 ◽  
Vol 25 (1) ◽  
pp. 50-54
Author(s):  
Maciej Abakumow ◽  
◽  
Krzysztof Kowalczuk ◽  
Keyword(s):  
Blood Pressure ◽  
Healthy Volunteers ◽  
High Altitude ◽  
Cardiovascular System ◽  
Preliminary Report ◽  
Pressure Increase ◽  
Blood Pressure Increase ◽  
Safety Considerations ◽  
Very High

Abstract: Apart from protection from very high altitude or influence of increased gravitational accelerations protective suits sometimes are used for another applications like supporting kinesitherapy. Because of some safety considerations connected with possible cardiovascular system overload and dangerous blood pressure increase we tested if these concerns are valid. Main aim ot presented research performed with participation of healthy volunteers was to confirm that use of High Altitude Protection (HAP) suit is safe in terms of increased cardiovascular.

Abstract MP09: Vascular Rho-kinase Activation by Inflammatory Signaling Mediates Blood Pressure Increase in Overweight

Hypertension ◽  
2014 ◽  
Vol 64 (suppl_1) ◽  
Author(s):  
Cristiane Aoqui Aoqui ◽  
Stefan Chmielewski ◽  
Uwe Heemann ◽  
Marcus Baumann
Keyword(s):  
Blood Pressure ◽  
Kinase Activity ◽  
Rho Kinase ◽  
Normal Weight ◽  
Mesenteric Arteries ◽  
Pressure Increase ◽  
Tnf Alpha ◽  
Kinase Activation ◽  
Blood Pressure Increase ◽  
Tlr4 Ligand

Background: Overweight is associated with a high prevalence of hypertension. The mechanisms linking overweight to blood pressure increase remain unclear. We hypothesized that vascular Rho-kinase activation contributes to blood pressure increase in overweight by involving TNF-α and TLR4. Methods: C57/BL6 mice fed a high-fat diet for 2 weeks were used to induce overweight associated blood pressure increase. Additional treatment in overweight and normal weight mice contained Rho-kinase inhibitors (fasudil and pravastatin; n=7/all groups), etanercept and TNFR1 and TLR4 null-mice. Microvascular studies were performed in a wire myograph and arterial blood pressure measured with a carotid catheter. Rho-kinase activity was determined in small mesenteric arteries of all groups. Inflammatory ligands such as TNF-alpha and free fatty acids were determined. Effects of TNF-alpha and TLR4 ligand LPS and palmitic acid on Rho-kinase activity and were determined ex vivo in mesenteric arteries and in in vivo. Results: Overweight mice had higher blood pressure (Delta: 9±2 mmHg) and vasoconstriction as normal weight mice. Small mesenteric arteries of overweight mice had a 50% higher Rho-kinase activity as normal weight mice. Ex vivo treatment with the Rho-kinase inhibitor Y-27632 reversed vasoconstriction of mesenteric arteries of overweight mice to constriction level in normal weight mice. In vivo treatment with the Rho-kinase inhibitor fasudil or pravastatin along with high-fat diet abolished the overweight associated blood pressure increase and enhanced vasoconstriction. TNF-alpha and TLR4 ligand free fatty acid were enhanced in overweight mice. TNF-alpha and TLR4 ligand LPS and palmitic acid increased Rho-kinase activity in mesenteric arteries. Use of etenercept, TNFR1 and TLR4 null-mice in the overweight model prevented blood pressure increase, vasoconstriction and Rho-kinase activation. All described effects were independent of adiposity. Conclusion: These results indicated that in diet-induced overweight vascular Rho-kinase activation is a key element of increased blood pressure and vasoconstriction. Potential activator of Rho-kinase are mediated by inflammatory factors including TLR4 ligands and TNF-alpha.

scholarly journals Recurrent Blood Pressure Rise after Treatment with Anti-vascular Endothelial Growth Factor Agents

2020 ◽  
Vol 237 (04) ◽  
pp. 454-457
Author(s):  
Iris Wyssmüller ◽  
Karen Schaal ◽  
Sebastian Wolf ◽  
Martin Zinkernagel
Keyword(s):  
Blood Pressure ◽  
Vascular Endothelial Growth Factor ◽  
Growth Factor ◽  
Systolic Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Pressure Increase ◽  
Vascular Endothelial ◽  
Blood Pressure Increase ◽  
Injection Process ◽  
Endothelial Growth Factor

Abstract Background It has previously been shown that the process of anti-vascular endothelial growth factor (VEGF) injections can lead to a significant increase of blood pressure. The aim of this study was to investigate whether this blood pressure increase was reproducible with repeated anti-VEGF injections. Patients and Methods Patients with a systolic blood pressure of ≥ 180 mmHg during previous injections who were scheduled for further injections were asked to participate in this study. Systolic as well as diastolic blood pressure was measured before, during, and after the intravitreal injection process. Results Thirty-nine patients (21 females, 18 males) with a mean age of 75 years (range 34 – 94 years) were included in this extension of the FEAR study. At first, clinical systolic blood pressure rose from an average of 157.3 ± 5.9 mmHg to 175 ± 6.7 mmHg at the time of the injection process (p < 0.01). Diastolic blood pressure rose from an average of 75.72 ± 4.2 mmHg to 84.44 ± 7.3 mmHg (p < 0.13) at the time of the injection process. Overall, the majority of the participants (56%, N = 22) had a systolic blood pressure of ≥ 180 mmHg. Conclusions Our results show that the blood pressure increase occurs persistently during the injection process in some patients. Repeated episodes of severe hypertension may predispose patients to cardiovascular events, especially those with concomitant cardiovascular risk factors.

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