scholarly journals An index of the fractal characteristic of an airway tree is associated with airflow limitations and future body mass index reduction in COPD patients

2020 ◽  
Vol 128 (5) ◽  
pp. 1280-1286
Author(s):  
Daisuke Kinose ◽  
Emiko Ogawa ◽  
Satoru Kawashima ◽  
Yumiko Matsuo-Kashiwagi ◽  
Ruriko Yukimura-Seto ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Airflow Limitation ◽  
Chronic Obstructive ◽  
Cross Sectional ◽  
Obstructive Pulmonary Disease ◽  
Index Reduction ◽  
Fractal Characteristic ◽  
Fractal Index ◽  
Airway Tree

An airway tree is a fractal object. We showed that the distribution of minimal inner cross-sectional area (iCSA) of airway branches can be expressed by a fractal index, D, of minimal iCSA. This D was correlated with airflow limitation and future body mass index reduction in chronic obstructive pulmonary disease patients, as predicted by Hess–Murray’s law.

scholarly journals RELATIONSHIP BETWEEN LEVEL OF SERUM ADIPONECTIN AND FRAILTY IN ELDERLY PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE

2020 ◽  
Vol 8 (2) ◽  
pp. 101
Author(s):  
Erika Marfiani ◽  
Jusri Ichwani ◽  
Novira Widajanti ◽  
Daniel Maranatha ◽  
Muhammad Amin
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Body Mass Index ◽  
Pulmonary Disease ◽  
Body Mass ◽  
Subcutaneous Fat ◽  
Airflow Limitation ◽  
Serum Adiponectin ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
The Relationship

Elderly are especially prone to the adverse health effects of chronic obstructive pulmonary disease (COPD). COPD is a typical aging disease which is found to be about 12% in the age group more than 64 years old. Frailty is an important geriatics syndrome, while adiponectin is an important adipokine that regulate homeostasis of energy. Adiponectin is affected by age, especially in males. Adiponectin levels increases as subcutaneous fat cells in older men decreases. Increased adiponectin can lead to muscle wasting which will further reduce body weight and body mass index (BMI), which indirectly also increases the degree of frailty. Until now the relationship between adiponectin with frailty degree in advanced COPD is still unknown.The aims of this study was to investigate the relationship between plasma adiponectin level and frailty in COPD elders. This was an observational analytic cross-sectional study. All anthropometric parameters, including weight, height, and body mass index (BMI), were measured. Adiponectin was measured by ELISA methods obtained from venous blood samples. Aged more than or equal to 60 years old, the patients underwent spirometry to determine the degree of airflow limitation and the degree of frailty defined by the Fried criteria. Statistic analysis used Rank Spearman. Thirty-eight male COPD patients became the subject of the study. The average age was 70-74 years, with a total of 13 robust, 12 prefrails and 13 frail patients. Level of adiponectin (mean and SD) in robust, prefrail, and frail were 6.84+ 2.66 , 6.58 + 4.27, and 11.62 + 4.90 respectively, p=0.015. Further analysis showed that level of adiponectin rose progresively with an increasing number of components of frailty. The degree of obstruction mostly with mild (42.1%), and no subjects with very severe. There were an increase in serum adiponectin levels in all subjects. In conclusion, level of adiponectin serum correlates positively with the degree of frailty.

scholarly journals Association between obesity and chronic obstructive pulmonary disease in Moroccan adults: Evidence from the BOLD study

2021 ◽  
Vol 9 ◽  
pp. 205031212110314
Author(s):  
Abdelilah Benslimane ◽  
Vanessa Garcia-Larsen ◽  
Khaoula El Kinany ◽  
Amina Alaoui Chrifi ◽  
Zineb Hatime ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Body Mass Index ◽  
Waist Circumference ◽  
Pulmonary Disease ◽  
Body Mass ◽  
Abdominal Obesity ◽  
Chronic Obstructive ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Obstructive Pulmonary Disease

Objective: The Moroccan cross-sectional study aimed to investigate obesity in association to chronic obstructive pulmonary disease in Fez city. Methods: A cross-sectional survey was carried out in Moroccan adults. Anthropometric and spirometry measurements were performed using standardized guidelines. Results: Among the 744 participants, 53.9% of were women, with a mean age of 55.27 years (SD = 10.29). Nearly all women declared themselves to be never smokers, while 21% of men were current smokers. Overall, chronic obstructive pulmonary disease prevalence decreased with body mass index ( p = 0.01) and waist circumference ( p < 0.001). The same trends were also observed in women. The adjusted regression analysis showed a significant independent association between chronic obstructive pulmonary disease and decreasing overweight (ORa: 0.66; CI95% (0.40–0.98)), obesity (ORa: 0.66 CI95%: (0.36–0.89)), and a decreasing waist circumference-abdominal obesity (ORa: 0.58 CI95%: (0.34–0.99)) in the whole population. The same association remains significant in women for overweight (ORa: 0.18 CI95%: (0.06–0.54)) and for waist circumference-abdominal obesity (ORa: 0.40 CI95%: (0.19–0.85)). All these associations disappeared for men. Conclusion: Chronic obstructive pulmonary disease decreases with the increase in body mass index and waist circumference. The effect of waist circumference on the chronic obstructive pulmonary disease was greater among women, regardless of the tobacco factor. A multicenter study would help to confirm the accuracy of these findings in a larger sample of the Moroccan population. Developed lifestyle programs in patients with chronic obstructive pulmonary disease should be considered.

Role of Capnograghy during weaning from mechanical ventilation in patients with chronic obstructive pulmonary disease

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Ramy Karem Ali Ali ◽  
Yasser Mosafa Mohammed Mostafa ◽  
Tamer Mohammed Ali
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Mechanical Ventilation ◽  
Pulmonary Disease ◽  
Airflow Limitation ◽  
Chronic Obstructive ◽  
Weaning From Mechanical Ventilation ◽  
Cross Sectional ◽  
Obstructive Pulmonary Disease ◽  
Chronic Inflammatory Response

Abstract Background Chronic obstructive pulmonary disease (COPD) is characterized by persistent airflow limitation associated with an enhanced chronic inflammatory response in the airway, acute exacerbations of COPD can lead to progressive respiratory failure necessitating mechanical ventilation. Weaning of these patients may prove difficult and a spontaneous breath trial should be provided before the decision of extubation. Aim To evaluate the role of capnograghy in COPD patients during weaning from mechanical ventilation. Subject and methods This was a cross sectional prospective study conducted on 50 patients who were admitted at the Respiratory Intensive Care Unit of Abbassia Chest hospital and diagnosed as COPD and on mechanical ventilation. During the weaning trial, the role of capnography device evaluated considering the ability of Pet CO2 parameter in predicting hypercapnia and subsequently weaning outcome Results The changes in ABG reading before and after the SBT, PaCO2 and Pet CO2 showed significant elevation at the end of SBT,P=0.001 for both, while O2 saturation was significantly decrease at the end of SBT, P0.001. Conclusion The study found that Pa CO2 and PetCO2 are correlated to each other before, during and after SBT. Most of the studies that was found reported that PetCO2 is highly correlated with Paco2 and that PetCO2 may be a rapid and reliable predictor of arterial PaCO2 in respiratory distress.

scholarly journals Association between depression and body mass index in patients with chronic obstructive pulmonary disease

2010 ◽  
Vol 9 (S1) ◽  
Author(s):  
Athanasios Tselebis ◽  
Dionisios Bratis ◽  
Maria Harikiopoulou ◽  
Elpida Theodorakopoulou ◽  
Georgios Moussas ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Body Mass Index ◽  
Pulmonary Disease ◽  
Body Mass ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease

scholarly journals Chronic obstructive pulmonary disease and body mass index in five Latin America cities: The PLATINO study

2008 ◽  
Vol 102 (5) ◽  
pp. 642-650 ◽  
Author(s):  
Maria Montes de Oca ◽  
Carlos Tálamo ◽  
Rogelio Perez-Padilla ◽  
José Roberto B. Jardim ◽  
Adriana Muiño ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Body Mass Index ◽  
Latin America ◽  
Pulmonary Disease ◽  
Body Mass ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease
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