scholarly journals Vestibular short-latency evoked potential abolished by low-frequency noise exposure in rats

2018 ◽  
Vol 119 (2) ◽  
pp. 662-667 ◽  
Author(s):  
Courtney E. Stewart ◽  
Ariane C. Kanicki ◽  
Richard A. Altschuler ◽  
W. M. King
Keyword(s):  
Evoked Potential ◽  
Noise Exposure ◽  
Low Frequency ◽  
Short Latency ◽  
Head Movements ◽  
Frequency Noise ◽  
Otolith Organs ◽  
Specific Class ◽  
Low Frequency Noise ◽  
Physiological Basis

The vestibular system plays a critical role in detection of head movements and is essential for normal postural control. Because of their anatomical proximity to the cochlea, the otolith organs are selectively exposed to sound pressure and are at risk for noise overstimulation. Clinical reports suggest a link between noise exposure and balance problems, but the structural and physiological basis for this linkage is not well understood. The goal of this study was to determine the effects of low-frequency noise (LFN) on the otolith organs by correlating changes in vestibular short-latency evoked potentials (VsEPs) with changes in saccular afferent endings following noise exposure. LFN exposure transiently abolished the VsEP and reduced the number of stained calyces within the sacculus. Although some recovery of the VsEP waveform could be observed within 3 days after noise, at 3 wk recovery was only partial in most animals, consistent with a reduced number of afferents with calyceal endings. These data show that a single intense noise exposure is capable of causing a vestibular deficit that appears to mirror the synaptic deficit associated with hidden hearing loss after noise-induced cochlear injury. NEW & NOTEWORTHY This is the first study to explore the effects of low-frequency high-intensity noise on vestibular short-latency evoked potential (VsEP) responses, which shows a linkage between attenuated noise-induced VsEPs and pathological changes to otolith organ afferents. This finding suggests a potential limitation of the VsEP for evaluation of vestibular dysfunction, since the VsEP measurement may assess the activity of a specific class rather than all afferents.

scholarly journals Factors influencing low-frequency noise reduction in typical Chinese dwelling layouts

2020 ◽  
pp. 146134842094297
Author(s):  
Yang Song ◽  
Jian Kang
Keyword(s):  
Noise Reduction ◽  
Noise Exposure ◽  
Noise Source ◽  
Low Frequency ◽  
Frequency Noise ◽  
Low Frequency Noise ◽  
Low Frequencies ◽  
Factors Influencing ◽  
Polyline Distance

Existing approaches to reducing the low-frequency noise exposure of dwellings are not always sufficient. This study investigated the significance of dwelling layout design for low-frequency noise control. The sound distribution in six typical Chinese dwelling layouts was analysed using in-situ measurements under steady-state noise of various low frequencies. The results showed that among two-bedroom dwelling layouts, the overall average noise reduction varied considerably (6 dB). The noise reduction for room levels (number of rooms sound crosses) 1–2 and 2–3 varies by 5 and 3 dB, respectively, and the noise reduction at door openings varies by 5 dB. A model to approximate the low-frequency noise reduction of a layout was developed using the polyline distance from the noise source and the number of walls the polyline has to cross, which were clearly shown to influence low-frequency noise reduction and seem to be the strongest investigated factors.

scholarly journals Low-Frequency Noise and Its Main Effects on Human Health—A Review of the Literature between 2016 and 2019

2020 ◽  
Vol 10 (15) ◽  
pp. 5205
Author(s):  
Juliana Araújo Alves ◽  
Filipa Neto Paiva ◽  
Lígia Torres Silva ◽  
Paula Remoaldo
Keyword(s):  
Hearing Loss ◽  
Cardiovascular Diseases ◽  
Human Health ◽  
Noise Exposure ◽  
Low Frequency ◽  
Frequency Noise ◽  
Low Frequency Noise ◽  
Review Of The Literature ◽  
Noise Annoyance ◽  
Main Effects

This paper summarizes the presently available knowledge about the association between low-frequency noise and its effects on health. A database was constructed with a total of 142 articles published between 2016 and 2019 regarding low-frequency noise exposure and its effects on health. A total of 39 articles were analysed in depth. The articles were divided into categories according to the effects on human health addressed. Regarding the emitting source, there was a greater number of articles addressing issues related to sources of environmental noise and noise from wind turbines. As for the effects generated on human health, there was a greater number of articles referring to the effects on sleep disorders, discomfort, sensitivity to and irritability from noise, annoyance, hearing loss, and cardiovascular diseases, and these effects are analysed in more detail in the present article.

scholarly journals How Can Low-Frequency Noise Exposure Interact with the Well-Being of a Population? Some Results from a Portuguese Municipality

2019 ◽  
Vol 9 (24) ◽  
pp. 5566 ◽  
Author(s):  
Juliana Araújo Alves ◽  
Lígia Torres Silva ◽  
Paula Remoaldo
Keyword(s):  
Urban Areas ◽  
Noise Exposure ◽  
Low Frequency ◽  
Noise Pollution ◽  
Well Being ◽  
Sound Level ◽  
Frequency Noise ◽  
Low Frequency Noise ◽  
Sound Levels ◽  
Exposed Population

Noise pollution is the second most harmful environmental stressor in Europe. Portugal is the fourth European country most affected by noise pollution, whereby 23.0% of the population is affected. This article aims to analyze the effects of exposure to low frequency noise pollution, emitted by power poles and power lines, on the population’s well-being, based on a study of “exposed” and “unexposed” individuals in two predominantly urban areas in north-western Portugal. To develop the research, we used sound level (n = 62) and sound recording measurements, as well as adapted audiometric test performance (n = 14) and surveys conducted with the resident population (n = 200). The sound levels were measured (frequency range between 10 to 160 Hz) and compared with a criterion curve developed by the Department for Environment, Food and Rural Affairs (DEFRA). The sound recorded was performed 5 m away from the source (400 kV power pole). Surveys were carried out with the “exposed” and “unexposed” populations, and adapted audiometric tests were performed to complement the analysis and to determine the threshold of audibility of “exposed” and “unexposed” volunteers. The “exposed” area has higher sound levels and, consequently, more problems with well-being and health than the “unexposed” population. The audiometric tests also revealed that the “exposed” population appears to be less sensitive to low frequencies than the “unexposed” population.

scholarly journals TRPV4-Activation Induced Nerve Fibers Injury Mediates the Memory Impairment After Noise Exposure

2021 ◽  
Author(s):  
Yang Yang ◽  
Ju Wang ◽  
Chuanyan Yang ◽  
Yulian Quan ◽  
Xuezhu Chen ◽  
...  
Keyword(s):  
Learning And Memory ◽  
Memory Impairment ◽  
Noise Exposure ◽  
Morphological Changes ◽  
Low Frequency ◽  
Recognition Task ◽  
Memory Deficits ◽  
Nerve Fibers ◽  
Frequency Noise ◽  
Low Frequency Noise

Abstract Background: Excessive exposure to high-intensity, low-frequency noise (HI-LFN) causes vibroacoustic disease (VAD). Memory deficits is one non-auditory symptomatic effect found in humans and rodents with VAD, but the mechanism is largely unknown. This study was designed to explore the nerve fibers impairment in hippocampus and potential mechanism after HI-LFN exposure.Methods: HI-LFN injury model was established by exposing to noises with a frequency of 100, 150 or 200 Hz and a pressure level of 140dB. Adult male WT and TRPV4-/- mice were employed in present study. After HI-LFN exposure, the new object recognition task and the morris water maze were used for examining the memory impairment, HE staining was used to examine the holistic morphological changes hippocampus, immunofluorescence and western blot were used to the detect the change of nerve fibers in dentate gyrus (DG) and CA1 of the hippocampus.Results: The expression of TRPV4 was significantly upregulated in hippocampus after HI-LFN exposure. What’s more, prominent learning and memory deficits and lower neural cell density with injured nerve fibers in CA1 and DG areas of hippocampus were found in WT mice after HI-LFN exposure. However, TRPV4-/- mice showed better performance in learning and memory tests and more integrated nerve fibers in CA1 and DG areas after HI-LFN exposure compared with that in WT mice.Conclusions: Our data indicated a novel mechanism that the injury of neurons and nerve fibers in hippocampus might be the primary trigger of memory deficits after HI-LFN exposure, and TRPV4 activation plays crucial role in the injury of neurons and nerve fibers in hippocampus, those findings provide a promising therapeutic target for treating cognitive dysfunction after low frequency noise exposure.

scholarly journals Intense noise exposure alters peripheral vestibular structures and physiology

2020 ◽  
Vol 123 (2) ◽  
pp. 658-669 ◽  
Author(s):  
C. E. Stewart ◽  
D. S. Bauer ◽  
A. C. Kanicki ◽  
R. A. Altschuler ◽  
W. M. King
Keyword(s):  
Hair Cells ◽  
Evoked Potential ◽  
Noise Exposure ◽  
Critical Role ◽  
Short Latency ◽  
Synaptic Function ◽  
Otolith Organs ◽  
Large Head ◽  
Intense Noise ◽  
Afferent Terminals

The otolith organs play a critical role in detecting linear acceleration and gravity to control posture and balance. Some afferents that innervate these structures can be activated by sound and are at risk for noise overstimulation. A previous report demonstrated that noise exposure can abolish vestibular short-latency evoked potential (VsEP) responses and damage calyceal terminals. However, the stimuli that were used to elicit responses were weaker than those established in previous studies and may have been insufficient to elicit VsEP responses in noise-exposed animals. The goal of this study was to determine the effect of an established noise exposure paradigm on VsEP responses using large head-jerk stimuli to determine if noise induces a stimulus threshold shift and/or if large head-jerks are capable of evoking VsEP responses in noise-exposed rats. An additional goal is to relate these measurements to the number of calyceal terminals and hair cells present in noise-exposed vs. non-noise-exposed tissue. Exposure to intense continuous noise significantly reduced VsEP responses to large stimuli and abolished VsEP responses to small stimuli. This finding confirms that while measurable VsEP responses can be elicited from noise-lesioned rat sacculi, larger head-jerk stimuli are required, suggesting a shift in the minimum stimulus necessary to evoke the VsEP. Additionally, a reduction in labeled calyx-only afferent terminals was observed without a concomitant reduction in the overall number of calyces or hair cells. This finding supports a critical role of calretinin-expressing calyceal-only afferents in the generation of a VsEP response. NEW & NOTEWORTHY This study identifies a change in the minimum stimulus necessary to evoke vestibular short-latency evoked potential (VsEP) responses after noise-induced damage to the vestibular periphery and reduced numbers of calretinin-labeled calyx-only afferent terminals in the striolar region of the sacculus. These data suggest that a single intense noise exposure may impact synaptic function in calyx-only terminals in the striolar region of the sacculus. Reduced calretinin immunolabeling may provide insight into the mechanism underlying noise-induced changes in VsEP responses.

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