Tandem Mass Spectrometry in Physiology

Physiology ◽  
2007 ◽  
Vol 22 (6) ◽  
pp. 390-400 ◽  
Author(s):  
Trairak Pisitkun ◽  
Jason D. Hoffert ◽  
Ming-Jiun Yu ◽  
Mark A. Knepper

Tandem mass spectrometry coupled to liquid chromatography (LC-MS/MS) allows identification of proteins in a complex mixture without need for protein purification (“shotgun” proteomics). Recent progress in LC-MS/MS-based quantification, phosphoproteomic analysis, and targeted LC-MS/MS using multiple reaction monitoring (MRM) has made LC-MS/MS a powerful tool for the study of cell physiology.

2017 ◽  
Vol 33 (7) ◽  
pp. 863-867 ◽  
Author(s):  
Maya KAMAO ◽  
Yoshihisa HIROTA ◽  
Yoshitomo SUHARA ◽  
Naoko TSUGAWA ◽  
Kimie NAKAGAWA ◽  
...  

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