scholarly journals Herpes Simplex Type 1 Encephalitis Restricted to the Brainstem in a Pediatric Patient

2010 ◽  
Vol 2010 ◽  
pp. 1-4 ◽  
Author(s):  
Juliana Harumi Arita ◽  
Jaime Lin ◽  
Mirella Maccarini Peruchi ◽  
Marcelo Masruha Rodrigues ◽  
Luiz Celso Pereira Vilanova
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Respiratory Failure ◽  
Herpes Simplex ◽  
Clinical Picture ◽  
Herpes Simplex Encephalitis ◽  
Herpes Simplex Type ◽  
Temporal Lobes ◽  
Consciousness Impairment

Herpes simplex encephalitis is a potentially fatal infection of central nervous system that typically involves frontal and temporal lobes. Occasionally, it presents an extratemporal involvement and in rarer cases, it is limited to the brainstem. We describe a case of an adolescent who presented with fever, sore throat, and vertigo. Clinical picture evolved to lethargy, tetraparesis, consciousness impairment, and respiratory failure. MRI showed lesions restricted to the brainstem. PCR of CSF was positive for herpes simplex type 1.

scholarly journals Influence of Perineurial Cells and Toll-Like Receptors 2 and 9 on Herpes simplex Type 1 Entry to the Central Nervous System in Rat Encephalitis

PLoS ONE ◽  
2010 ◽  
Vol 5 (8) ◽  
pp. e12350 ◽  
Author(s):  
Biborka Bereczky-Veress ◽  
Nada Abdelmagid ◽  
Fredrik Piehl ◽  
Tomas Bergström ◽  
Tomas Olsson ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Herpes Simplex ◽  
Herpes Simplex Type ◽  
Toll Like Receptors ◽  
The Central Nervous System ◽  
Perineurial Cells

Infections of the CNS: Meningitis and Encephalitis (DRAFT)

2018 ◽  
Author(s):  
Tamara Kaplan ◽  
Tracey Milligan
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Herpes Simplex ◽  
Herpes Simplex Encephalitis ◽  
Altered Level ◽  
Limbic Structures ◽  
Temporal Lobes ◽  
Nuchal Rigidity ◽  
Level Of Consciousness ◽  
The Central Nervous System

The video in this chapter discusses infections of the central nervous system (CNS), meningitis including its symptoms (fever, headache, nuchal rigidity, altered level of consciousness), its causes (bacterial, fungal, viral, or aseptic), and how the CSF profile provides clues to the etiology. The chapter also discusses encephalitis, its symptoms (seizures, other focal neurologic symptoms). Patients with Herpes Simplex Encephalitis may show T2 hyperintensities in the anterior temporal lobes and limbic structures on MRI. CSF may show xanthochromia and positive PCR for HSV1 or HSV2.

Central Nervous System Delivery of Interleukin 4 by a Nonreplicative Herpes Simplex Type 1 Viral Vector Ameliorates Autoimmune Demyelination

1998 ◽  
Vol 9 (17) ◽  
pp. 2605-2617 ◽  
Author(s):  
R. Furlan ◽  
P. L. Poliani ◽  
F. Galbiati ◽  
A. Bergami ◽  
L. M. E. Grimaldi ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Herpes Simplex ◽  
Viral Vector ◽  
Interleukin 4 ◽  
Herpes Simplex Type ◽  
Autoimmune Demyelination
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