scholarly journals Myelodysplastic Syndrome and Autoimmunity: A Case Report of an Unusual Presentation of Myelodysplastic Syndrome

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Andrea L. Merrill ◽  
Hedy Smith
Keyword(s):  
Case Report ◽  
Connective Tissue ◽  
Myelodysplastic Syndrome ◽  
Lacrimal Gland ◽  
Case Reports ◽  
Connective Tissue Diseases ◽  
Case Series ◽  
Organizing Pneumonia ◽  
Trisomy 8 ◽  
Autoimmune Phenomena

Myelodysplastic syndrome (MDS) commonly presents asymptomatically or with symptomatic cytopenias. However, autoimmune phenomena in association with MDS have been well described in several case reports and case series. Typically, these autoimmune phenomena take the form of vasculitides, arthritis, connective tissue diseases, pulmonary infiltrates, or polymyalgia rheumatica. We present the case of a woman with MDS (karyotype 46,XX,+1,der(1;7)(q10;p10)[20], that evolved with an additional trisomy 8 clone) and a novel spectrum of autoimmune diseases including acute fibrinous and organizing pneumonia (AFOP) and lacrimal gland pseudotumor.

scholarly journals Organizing pneumonia as the initial presentation in rheumatoid arthritis – A case report

2021 ◽  
Vol 5 (1) ◽  
pp. 051-053
Author(s):  
Kaur Harveen ◽  
Singh Dilbag ◽  
Pandhi Naveen
Keyword(s):  
Rheumatoid Arthritis ◽  
Case Report ◽  
Interstitial Lung Disease ◽  
Connective Tissue ◽  
Lung Injury ◽  
Lung Disease ◽  
Connective Tissue Diseases ◽  
Pulmonary Involvement ◽  
Organizing Pneumonia ◽  
Initial Manifestation

Organizing pneumonia (OP), can be seen in association with lung injury, infection, drug intoxication, and connective tissue diseases. Patients of rheumatoid arthritis (RA) are prone to develop interstitial lung disease (ILD), but the pulmonary involvement usually occurs several years after the joint manifestations. Only in about 10% cases of RA, the initial manifestation of the disease can be in the form of interstitial lung disease. OP as the initial manifestation of RA is extremely uncommon occurrence. Here is presented a case of 52-year-old male who presented with OP as the initial manifestation of RA. On investigation, the RA factor and anti-CCP Antibodies were positive. Based on clinical, radiological and histopathological findings the diagnosis was established.

scholarly journals Myelodysplastic syndrome with clonal karyotype evolution associated with trisomy 8 and ASXL1 mutation in well‐controlled HIV patient: Case report and literature review

eJHaem ◽  
2020 ◽  
Vol 1 (1) ◽  
pp. 344-349
Author(s):  
Daniela Palheiro Mendes‐de‐Almeida ◽  
Viviane Lamim Lovatel ◽  
Filipe Vicente Santos‐Bueno ◽  
Elaiza Almeida Antônio Kós ◽  
Francianne Gomes Andrade ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Myelodysplastic Syndrome ◽  
Karyotype Evolution ◽  
Patient Case ◽  
Trisomy 8

scholarly journals Solitary fibrous tumors of the spine: a pediatric case report with a comprehensive review of the literature

2017 ◽  
Vol 19 (3) ◽  
pp. 339-348 ◽  
Author(s):  
Gregory W. Albert ◽  
Murat Gokden
Keyword(s):  
Case Report ◽  
Case Reports ◽  
Case Series ◽  
Review Of The Literature ◽  
Benign Lesions ◽  
Pediatric Case ◽  
Comprehensive Review ◽  
Solitary Fibrous Tumors ◽  
Small Case Series

Solitary fibrous tumors of the spine are rare lesions. Their description in the literature is limited to case reports and small case series. While generally benign lesions, they can recur and occasionally occur as malignancies. Here the authors present the case of a 10-year-old boy, the youngest patient and first preadolescent reported thus far, with this condition. In addition, they perform a comprehensive review of all previously published cases of spinal solitary fibrous tumors.

Ulnar artery vasculopathy: a common but nonspecific feature of systemic sclerosis

2017 ◽  
Vol 2 (3) ◽  
pp. 221-224
Author(s):  
Tae-Jong Kim ◽  
Soon-Young Song ◽  
Hee Chang Ahn ◽  
Yoon-Kyoung Sung ◽  
Sang-Cheol Bae ◽  
...  
Keyword(s):  
Systemic Sclerosis ◽  
Connective Tissue ◽  
Lupus Erythematosus ◽  
Connective Tissue Diseases ◽  
Case Series ◽  
Ulnar Artery ◽  
Common Finding ◽  
Clinical Factors ◽  
Vessel Disease ◽  
Large Vessel Disease

Introduction Systemic sclerosis (SSc) is characterized by microvascular abnormalities and fibrosis. Several studies have reported that large vessel disease is also common in SSc. The aim of this case series was to investigate whether ulnar artery involvement in patients with SSc is a disease-specific phenomenon, as compared to other connective tissue diseases (CTD). Methods A total of 28 patients, including 7 with SSc and 12 with systemic lupus erythematosus (SLE), underwent brachial arteriography due to severe Raynaud's phenomenon and/or digital ulcerations and were enrolled in the study. They were divided into two groups: an SSc/SSc-overlap group and a non-SSc group. The collection of the clinical parameters was conducted to investigate the associations between clinical factors and the ulnar artery vasculopathy. Results The SSc/SSc-overlap group (n = 10) consisted of 7 patients with SSc and 3 with features overlapping SSc. In the non-SSc group (n = 18), 12 cases of SLE, 2 of mixed connective tissue disease, 1 of dermatomyositis + SLE, 1 of rheumatoid arthritis, 1 of Sjogren's syndrome, and 1 case of skin vasculitis, were included. The relative frequencies of ulnar artery involvement were not significantly different between the SSc/SSc-overlap and non-SSc groups, respectively (n = 6, 60% vs. n = 9, 50%, p = 0.611). Conclusions Although ulnar artery involvement was frequently detected in patients with SSc/SSc-overlap, it was also a common finding in other CTDs; therefore, it is not specific to SSc or SSc-overlap diseases.

scholarly journals Obinutuzumab in connective tissue diseases after former rituximab-non-response: a case series

2022 ◽  
pp. annrheumdis-2021-221756
Author(s):  
Peter Kvacskay ◽  
Wolfgang Merkt ◽  
Janine Günther ◽  
Norbert Blank ◽  
Hanns-Martin Lorenz
Keyword(s):  
Connective Tissue ◽  
Connective Tissue Diseases ◽  
Case Series

Fatal Complications of Nasogastric Tube Misplacement in Two Dogs

2021 ◽  
Author(s):  
Jenniffer Rodriguez-Diaz ◽  
Julia P. Sumner ◽  
Meredith Miller
Keyword(s):  
Risk Factors ◽  
Case Report ◽  
Enteral Nutrition ◽  
Case Reports ◽  
Case Series ◽  
Feeding Tube ◽  
Tracheobronchial Tree ◽  
Human Medicine ◽  
Feeding Tubes ◽  
Fatal Complications

ABSTRACT Provision of enteral nutrition via the use of nasoenteric feeding tubes is a commonly used method in both veterinary and human medicine. Although case reports in human medicine have identified fatalities due to misplacement of nasogastric (NG) tubes into the tracheobronchial tree and subsequent pneumothorax, there are no case reports, to our knowledge, of fatalities in veterinary patients. This case report describes two fatalities caused by misplaced NG tubes in intubated patients (one intraoperative, one postoperative). This report highlights risk factors for feeding tube complications and methods to prevent future fatalities such as two-view radiography, two-step insertion, capnography, laryngoscopic-assisted placement, and palpation of the NG tube in the stomach. The recent fatalities discussed within this case series demonstrate that deaths as a result of NG tubes misplaced into the tracheobronchial tree occur in veterinary patients, and measures should be taken to prevent this complication.

scholarly journals Two-Year Outcome of Aflibercept for the Treatment of Choroidal Neovascularization in Punctate Inner Choroidopathy

2019 ◽  
Vol 10 (1) ◽  
pp. 24-31 ◽  
Author(s):  
Luis Arrevola ◽  
María Almudena Acero ◽  
María Jesús Peral
Keyword(s):  
Visual Acuity ◽  
Case Report ◽  
Choroidal Neovascularization ◽  
Single Case ◽  
Case Reports ◽  
Oral Prednisone ◽  
Case Series ◽  
Punctate Inner Choroidopathy ◽  
Single Case Report ◽  
The Right

Punctate inner choroidopathy (PIC) is a rare inflammatory chorioretinopathy that predominantly affects young myopic women. Visual prognosis is generally good, but occurrence of choroidal neovascularization (CNV) is common and may be vision threatening. Case reports and short case series support the effectiveness of intravitreal anti-vascular endothelial growth factor (VEGF) agents (ranibizumab and bevacizumab) for CNV associated with PIC given their anti-angiogenic and anti-inflammatory effects. Evidence concerning aflibercept, a more recent intravitreal anti-VEGF, is limited to a single case report. In this case report, we illustrate the case of a 43-year-old myopic woman presenting with visual acuity loss and distortion in the right eye over the last 5 days in whom CNV associated with PIC was diagnosed. Treatment with 1 injection per month of intravitreal aflibercept for 2 months and full-dose oral prednisone for 1 week, being tapered afterwards, improved visual acuity and resolved CNV, with benefits lasting up to 24 months.

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