scholarly journals Chiropractic Treatment for Gastrointestinal Problems: A Systematic Review of Clinical Trials

2011 ◽  
Vol 25 (1) ◽  
pp. 39-40 ◽  
Author(s):  
E Ernst
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Gastrointestinal Disorders ◽  
Publication Date ◽  
Controlled Clinical Trials ◽  
Chiropractic Treatment ◽  
Gastrointestinal Problem ◽  
Gastrointestinal Problems ◽  
Infant Colic ◽  
Present Systematic Review

Many chiropractors believe that chiropractic treatments are effective for gastrointestinal disorders. The aim of the present systematic review was to critically evaluate the evidence from controlled clinical trials supporting or not supporting this notion. Six electronic databases were searched for relevant studies. No limits were applied to language or publication date. Prospective, controlled, clinical trials of any type of chiropractic treatment for any type of gastrointestinal problem, except infant colic, were included. Only two trials were found – one was a pilot study, and the other had reached a positive conclusion; however, both had serious methodological flaws. There is no supportive evidence that chiropractic is an effective treatment for gastrointestinal disorders.

scholarly journals The effectiveness of surgical and non-surgical techniques in orthodontic practice in closing post-extraction spaces: a systematic review

2021 ◽  
Vol 19 (1) ◽  
pp. 31-38
Author(s):  
Z. S. Khabadze ◽  
M. E. Balashova
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Side Effects ◽  
Orthodontic Treatment ◽  
Surgical Techniques ◽  
Long Term Results ◽  
Publication Date ◽  
Controlled Clinical Trials ◽  
Surgical Methods

Reducing the orthodontic treatment duration is an important issue, especially for adult patients who want to complete treatment faster due to social or aesthetic reasons. In addition, an increase in the duration of orthodontic treatment has a number of side effects, therefore, orthodontists and patients are interested in the use of techniques that can accelerate the movement of teeth. Shorter treatment times can be achieved through a combination of orthodontic and surgical or non-surgical techniques.Aim. To systematically evaluate scientific data on the effectiveness and side effects of surgical and non-surgical methods in accelerating orthodontic treatment in situations with the removal of premolars and subsequent closure of the post-extraction spaces.Materials and methods. Electronic search of articles was carried out using search engines and databases: Cyberleninka, eLIBRARY, Google Scholar, Pub Med, SCOPUS. The publication date criterion was selected from January 2010 to January 2021. Articles included in the systematic review had to meet the following inclusion criteria: controlled clinical trials and randomized controlled clinical trials conducted in humans and published in the last 11 years in English language. The systematic review included and analyzed 15 full-text articles.Result. According to the systematic review, the speed of movement of teeth increases 2 times with corticotomy, and 1.5 times with piezocorticotomy, which is consistent with the data of other studies. At the same time, the effectiveness of the movement remains for no more than 2 months after the intervention.Conclusions. The corticotomy procedure reduces the treatment time in comparison with traditional methods by 30-50% (6-8 months). The investigated techniques did not have a significant effect on the depth of probing, the level of attachment, on the density of bone tissue, rotation and inclination of the moved teeth. Since no complications were identified for 2-4 months of observation, further studies are required to assess long-term results in the long term.

scholarly journals Clinical effectiveness of convalescent plasma in hospitalized patients with COVID-19: a systematic review and meta-analysis

2021 ◽  
Vol 15 ◽  
pp. 175346662110280
Author(s):  
Roberto Ariel Abeldaño Zuñiga ◽  
Ruth Ana María González-Villoria ◽  
María Vanesa Elizondo ◽  
Anel Yaneli Nicolás Osorio ◽  
David Gómez Martínez ◽  
...  
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Clinical Improvement ◽  
Data Extraction ◽  
Meta Analysis ◽  
Clinical Effectiveness ◽  
Risk Of Bias ◽  
Hospitalized Patients ◽  
Low Risk ◽  
Controlled Clinical Trials

Aims: Given the variability of previously reported results, this systematic review aims to determine the clinical effectiveness of convalescent plasma employed in the treatment of hospitalized patients diagnosed with COVID-19. Methods: We conducted a systematic review of controlled clinical trials assessing treatment with convalescent plasma for hospitalized patients diagnosed with SARS-CoV-2 infection. The outcomes were mortality, clinical improvement, and ventilation requirement. Results: A total of 51 studies were retrieved from the databases. Five articles were finally included in the data extraction and qualitative and quantitative synthesis of results. The overall risk of bias in the reviewed articles was established at low-risk only in two trials. The meta-analysis suggests that there is no benefit of convalescent plasma compared with standard care or placebo in reducing the overall mortality and the ventilation requirement. However, there could be a benefit for the clinical improvement in patients treated with plasma. Conclusion: Current results led to assume that the convalescent plasma transfusion cannot reduce the mortality or ventilation requirement in hospitalized patients diagnosed with SARS-CoV-2 infection. More controlled clinical trials conducted with methodologies that ensure a low risk of bias are still needed. The reviews of this paper are available via the supplemental material section.

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