scholarly journals Pyridinedicarboxylic Acid Derivatives of Dichlorobis(cyclopentadienyl)titanium(IV)

2012 ◽  
Vol 9 (1) ◽  
pp. 277-281
Author(s):  
Satish C. Dixit ◽  
Rohit K. Singh
Keyword(s):  
Dicarboxylic Acid ◽  
Spectral Data ◽  
Quinolinic Acid ◽  
Magnetic Moment ◽  
Electrical Conductance ◽  
Dicarboxylic Acids ◽  
Pyridinedicarboxylic Acid ◽  
Pyridine Dicarboxylic Acid ◽  
Elemental Analyses ◽  
Derivatives Of

Reactions of dichlorobis(cyclopentadienyl)titanium(IV) with pyridine dicarboxylic acidsviz. quinolinic acid (QAH2), 2,4-pyridine dicarboxylic acid (PAH2), isocinchomeronic acid (IAH2), cinchomeronic acid (CAH2) and dinicotinic acid (DAH2) were carried out in different stoichiometric ratios. Complexes of the type Cp2Ti(QAH)Cl, Cp2Ti(QAH)2, Cp2Ti(PAH)Cl, Cp2Ti(PAH)2, Cp2Ti(IAH)Cl, Cp2Ti(IAH)2, Cp2Ti(CAH)Cl, Cp2Ti(CAH)2, Cp2Ti(DAH)Cl and Cp2Ti(DAH)2were obtained. These new complexes were characterized on the basis of their elemental analyses, electrical conductance, magnetic moment and spectral data.

scholarly journals Some New Derivatives of Organozirconium(IV) with Pyridinedicarboxylic Acids

2012 ◽  
Vol 9 (2) ◽  
pp. 744-748
Author(s):  
Satish C. Dixit ◽  
Rohit K. Singh
Keyword(s):  
Dicarboxylic Acid ◽  
Spectral Data ◽  
Magnetic Moment ◽  
Electrical Conductance ◽  
Pyridine Dicarboxylic Acid ◽  
Elemental Analyses ◽  
Stoichiometric Ratios ◽  
Derivatives Of ◽  
Pyridinedicarboxylic Acids

Reactions of dichlorobis(cyclopentadienyl)zirconium(IV) with pyridinedicarboxylic acidsviz. quinolinic acids (QAH2), 2,4-pyridine dicarboxylic acid (PAH2), isocinchomeronic acid (IAH2), cinchomeronic acid (CAH2) and dinicotinic acid (DAH2) were carried out in different stoichiometric ratios. Complexes of the type Cp2Zr(QAH)Cl, Cp2Zr(QAH)2, Cp2Zr(PAH)Cl, Cp2Zr(PAH)2, Cp2Zr(IAH)Cl, Cp2Zr(IAH)2, Cp2Zr(CAH)Cl, Cp2Zr(CAH)2, Cp2Zr(DAH)Cl and Cp2Zr(DAH)2were obtained. These new complexes were characterized on the basis of their elemental analyses, electrical conductance, magnetic moment and spectral data.

scholarly journals Synthesis and Characterization of Some Novel Schiff Base Complexes of Oxovanadium(IV) Cation

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
A. K. Yadava ◽  
H. S. Yadav ◽  
Sanjay Singh ◽  
U. S. Yadav ◽  
D. P. Rao
Keyword(s):  
Schiff Base ◽  
Spectral Data ◽  
Magnetic Moment ◽  
Electrical Conductance ◽  
Schiff Base Complexes ◽  
Synthesis And Characterization ◽  
Electronic Spectral Data ◽  
Elemental Analyses ◽  
Tetraazamacrocyclic Ligands

A series of oxovanadium(IV) complexes of the type [VO(mac)]SO4(where mac = tetraazamacrocyclic ligands derived from condensation of 4,4,4-trifluro-1-(2-furyl)-1,3-butanedione or 4,4,4-trifluro-1-(2-thenyl)-1,3-butanedione withp-phenylenediamine and their reaction withβ-diketones) have been prepared using oxometal ion of vanadium as kinetic template. These complexes have been ascertained by electrical conductance, magnetic moment, elemental analyses, infrared, e.s.r. and electronic spectral data. All the oxovanadium(IV) complexes are five-coordinate ones.

scholarly journals Pharmacological activity of new imidazole-4,5-dicarboxylic acid derivatives in dopaminergic transmission suppression ttests in mice and rats

2020 ◽  
Vol 6 (4) ◽  
pp. 51-57
Author(s):  
Ekaterina E. Yakovleva ◽  
Eugeny R. Bychkov ◽  
Maria M. Brusina ◽  
Levon B. Piotrovsky ◽  
Petr D. Shabanov
Keyword(s):  
Locomotor Activity ◽  
Dicarboxylic Acid ◽  
Open Field ◽  
Field Test ◽  
Open Field Test ◽  
Dicarboxylic Acids ◽  
Dopaminergic Transmission ◽  
Dose Dependent ◽  
Derivatives Of ◽  
Experimental Improvement

Objective: To study the antiparkinsonian activity of new 1,2-substituted imidazole-4,5-dicarboxylic acids in dopaminergic transmission suppression tests in mice and rats. Materials and methods: On a model of reserpine extrapyramidal disorders, the derivatives of imidazole-dicarboxylic acids (IEM2258, IEM2248, IEM2247) were injected into the lateral brain ventricles of the mice 30 minutes after injecting reserpine at the doses of 0.1–0.5 mmol. Locomotor activity was analyzed in the Open-field test 2 hours later. In the catalepsy model, the studied agents were injected, using a pre-implanted cannula, with a simultaneous intraperitoneal injection of haloperidol. The severity of catalepsy was assessed with the Morpurgo method. Amantadine was used as a comparator drug in all the tests. Results: It was shown that IEM2258 significantly increased the main indicators of locomotor activity in the Open-field test at all the studied doses. The value of the antiparkinsonian effect of IEM2258 at doses of 0.4–0.5 mmol significantly exceeded that of amantadine. The antiparkinsonian effect of IEM2247 was maximally expressed and was significantly different from those in the control and comparator group at doses of 0.2 and 0.3 mmol. For all the experimental groups, a significant decrease in the manifestations of catalepsy in comparison with control indexes was determined. Discussion: The results made it possible to suggest the involvement of imidazole-4,5-dicarboxylic acids derivatives in the process of experimental improvement of dopaminergic neuromodulation and efficiency in animals. Conclusion: The data showed a significant dose-dependent antiparkinsonian activity of new imidazole-4,5-dicarboxylic acid derivatives, which makes it promising to develop these agents and to further search for effective and safe antiparkinsonian drugs in this pharmacological class. Graphical abstract

scholarly journals Synthetic, structural and antifungal studies of coordination compounds of Ru(III), Rh(III) and Ir(III) with tetradentate schiff bases

2006 ◽  
Vol 71 (8-9) ◽  
pp. 917-928 ◽  
Author(s):  
V.K. Sharma ◽  
Ankita Srivastava ◽  
Shipra Srivastava
Keyword(s):  
Spectral Data ◽  
Schiff Bases ◽  
Magnetic Moment ◽  
Coordination Compounds ◽  
Mass Spectra ◽  
Thermal Analyses ◽  
Agar Plate ◽  
Plate Method ◽  
Elemental Analyses ◽  
Fab Mass Spectra

A series of octahedral Ru(III), Rh(III) and Ir(III) complexes have been prepared with tetradentate Schiff bases derived by condensing isatin with 1,2-diaminoethane, 1,3-diaminopropane, 1,4-diaminobutane, 1,2-diaminobenzene and 1,3-diaminobenzene. The obtained complexes were characterized on the basis of their elemental analyses, magnetic moment, conductance, IR electronic, 1HNMR and FAB mass spectra, as well as thermal analyses. The Ru(III) complexes are low spin paramagnetic, while Rh(III) and Ir(III) behave as diamagnetic complexes. The IR spectral data revealed that all the Schiff bases behave as tetradentate and are coordinated to Ru(III), Rh(III) and Ir(III) via nitrogen and oxygen. Antifungal studies of the ligands as well as their complexes were carried out by the agar plate method.

New heterocycles derived from 2-aminothiophenol

1971 ◽  
Vol 24 (2) ◽  
pp. 405 ◽  
Author(s):  
JL Huppatz ◽  
RMJ Moore
Keyword(s):  
Dicarboxylic Acid ◽  
Spectral Data ◽  
Sulphuric Acid ◽  
Propionic Acid ◽  
Sodium Borohydride ◽  
Polyphosphoric Acid ◽  
Heterocyclic Ring ◽  
Phosphoryl Chloride ◽  
Alternative Synthesis ◽  
Derivatives Of

2-Aminothiophenol reacted with β-propiolactone in ethanol to give β-[o- (β-carboxyethylamino)phenylthio]propionic acid (1) which underwent cyclodehydration in polyphosphoric acid to give derivatives of two new heterocyclic ring systems, viz., 1,8-dioxo-1,2,3,4,5,6,7,8-octahydro-4- thia-5-azaphenanthrene (2) and 4,8-dioxo-3,4,7,8-tetrahydro-2H,6H- [1,4]thiazepino[2,3,4-ij]quinoline (3). Analytical and spectral data are presented which support the structures proposed for these compounds. ��� Alternative synthesis of each heterocycle was achieved by using media other than polyphosphoric acid to cyclize the dicarboxylic acid (1). Phosphoryl chloride gave β-(4-oxo-2,3,4,5-tetrahydro-1,5- benzothiazepin-5-yl)propionic acid (4), which was cylodehydrated smoothly to the thiazepine (3). Concentrated sulphuric acid afforded β- (4-oxo-1,2,3,4-tetrahydroquinol-8-ylthio)propionic acid (6) which was converted into the thiazaphenanthrene (2) by polyphosphoric acid. ��� Bromination reactions and reduction with sodium borohydride of the thiazepine (3) are also described.

scholarly journals Biocatalytic conversion of lignin to aromatic dicarboxylic acids in Rhodococcus jostii RHA1 by re-routing aromatic degradation pathways

2015 ◽  
Vol 17 (11) ◽  
pp. 4974-4979 ◽  
Author(s):  
Zoe Mycroft ◽  
Maria Gomis ◽  
Paul Mines ◽  
Paul Law ◽  
Timothy D. H. Bugg
Keyword(s):  
Dicarboxylic Acid ◽  
Dicarboxylic Acids ◽  
Degradation Pathways ◽  
Gene Insertion ◽  
Pyridine Dicarboxylic Acid ◽  
Aromatic Dicarboxylic Acids ◽  
Aromatic Degradation ◽  
Rhodococcus Jostii Rha1 ◽  
Rhodococcus Jostii

A gene insertion approach is used in Rhodococcus jostii RHA1 to generate pyridine-dicarboxylic acid bioproducts from lignin.

Study on a Structure of 2,6-pyridine-dicarboxylic Acid Cobalt Calcium Hexahydrate

2013 ◽  
Vol 739 ◽  
pp. 30-33
Author(s):  
Hai Xing Liu ◽  
Jing Zhong Xiao ◽  
Huan Mei Guo ◽  
Qing Hua Zhang ◽  
Zhang Xue Yu ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Hydrogen Bonding ◽  
Dicarboxylic Acid ◽  
Hydrothermal Reaction ◽  
Crystal Packing ◽  
X Ray Diffraction ◽  
X Ray ◽  
Hydrogen Bonding Interactions ◽  
Pyridinedicarboxylic Acid ◽  
Pyridine Dicarboxylic Acid

The complex C28H32CaCoN4O24has been synthesized from hydrothermal reaction and the crystal structure has been determined by means of single-crystal X-ray diffraction. The Co atom is six-coordinated by two N atoms, four O atoms from two 2,6-pyridinedicarboxylic acid. The Ca atom is eight-coordinated by two N atoms, six O atoms from two 2,6-pyridinedicarboxylic acid and two water molecular. The crystal packing is stabilized by O-H...O hydrogen bonding interactions.

scholarly journals SYNTHESIS, SPECTROSCOPIC, THERMAL AND BIOLOGICAL STUDIES ON MANGANESE(III), IRON(III) AND COBALT(III) COMPLEXES WITH BIS(MERCAPTO AZOLES)

2021 ◽  
Vol 9 (11) ◽  
pp. 351-362
Author(s):  
Shilpi Srivastava ◽  
Keyword(s):  
Thermal Stability ◽  
Sodium Hydroxide ◽  
1H Nmr ◽  
Magnetic Moment ◽  
Electrical Conductance ◽  
Antibacterial Activities ◽  
Nmr Data ◽  
Biological Studies ◽  
Elemental Analyses ◽  
Binuclear Products

Complexes of bis(mercapto azoles) i.e. bis(mercapto triazoles), bis(mercapto thiadiazoles) and bis(mercapto oxadiazoles) (LH2) with manganese(III), iron(III) and cobalt(III) have been prepared in methanol in the presence of sodium hydroxide and binuclear products of the type Na[M(L)2(H2O)2] have been isolated. Tentative structural conclusions are drawn for these complexes based upon elemental analyses, electrical conductance, magnetic moment and spectral (electronic, infrared and 1H NMR) data. The thermal stability and mode of decomposition for the complexes have been studied by TG, DTA and DSC techniques. The antifungal, antiviral and antibacterial activities of the ligands and their corresponding complexes were also investigated.

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