scholarly journals Traditional Herbal Medicine: A Review of Potential of Inhibitory Hepatocellular Carcinoma in Basic Research and Clinical Trial

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Zhidong Wang ◽  
Jun Li ◽  
Yuanyuan Ji ◽  
Peng An ◽  
Shu Zhang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Herbal Medicine ◽  
Herbal Remedy ◽  
Low Cost ◽  
Basic Research ◽  
Traditional Herbal Medicine ◽  
Aggressive Cancer ◽  
Low Toxicity ◽  
Arterial Chemoembolization

Although significantly develops in hepatocellular carcinoma (HCC), features of HCC remain an aggressive cancer with a dismal outcome. Traditional Chinese medicine (TCM), specifically Chinese herbal medicine (CHM), is one of the most popular complementary and alternative medicine modalities worldwide. The use of heat-clearing and detoxicating (Chinese namedqingre jiedu) CHM has attracted great attention as an alternative antitumor including HCC considering its low toxicity and high activity. Together these reports indicate that CHM is a promising anti-HCC herbal remedy in basic research. For patients with advanced HCC, CHM including formula and single combined with transcatheter arterial chemoembolization or chemotherapy is able to decrease tumor growth and the side effect of toxicity and improve overall survival, quality of life, and immune function. Due to its abundance, low cost, and safety in consumption, CHM remains a species with tremendous potential for further investigation in HCC.

Nano Phytomedicine Based Delivery System for CNS Disease

2020 ◽  
Vol 21 (9) ◽  
pp. 661-673 ◽  
Author(s):  
Mohammed Asadullah Jahangir ◽  
Chettupalli Anand ◽  
Abdul Muheem ◽  
Sadaf Jamal Gilani ◽  
Mohamad Taleuzzaman ◽  
...  
Keyword(s):  
Herbal Medicine ◽  
Low Cost ◽  
Herbal Medicines ◽  
Herbal Drugs ◽  
Widespread Acceptance ◽  
The Central Nervous System ◽  
Low Toxicity ◽  
Ancient Times ◽  
Plant Sources ◽  
Herbal Formulations

Herbal medicines are being used since ancient times and are an important part of the alternative and traditional medicinal system. In recent decades, scientists are embracing herbal medicines based on the fact that a number of drugs that are currently in use are derived directly or indirectly from plant sources. Moreover, herbal drugs have lesser side effects, albeit are potentially strong therapeutic agents. The herbal medicine market is estimated to be around US $62 billion globally. Herbal medicine has gained widespread acceptance due to its low toxicity, low cost, ease of accessibility and efficacy in treating difficult diseases. Safety and efficacy are another important factors in the commercialization process of herbal medicines. Nanotechnology has been shown to be potentially effective in improving the bioactivity and bioavailability of herbal medicines. Development of nano-phytomedicines (or by reducing the size of phytomedicine), attaching polymers with phytomedicines and modifying the surface properties of herbal drugs, have increased the solubility, permeability and eventually the bioavailability of herbal formulations. Novel formulations such as niosomes, liposomes, nanospheres, phytosomes etc., can be exploited in this area. This article reviews herbal medicines, which have prominent activity in the Central Nervous System (CNS) disorders and reported nano-phytomedicines based delivery systems.

scholarly journals Two Rare Metachronous Metastases of Hepatocellular Carcinoma After Liver Transplantation

2013 ◽  
Vol 98 (4) ◽  
pp. 432-436 ◽  
Author(s):  
Satoshi Shinya ◽  
Tomoaki Noritomi ◽  
Yasushi Yamauchi ◽  
Takamistu Sasaki ◽  
Yoshihiro Hamada ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Transplantation ◽  
Intracerebral Hematoma ◽  
Superior Mediastinum ◽  
Histopathologic Diagnosis ◽  
Frequent Relapses ◽  
Intracranial Metastases ◽  
Hcc Recurrence ◽  
Arterial Chemoembolization

Abstract A 59-year-old male with hepatocellular carcinoma (HCC) due to liver cirrhosis caused by the hepatitis C virus underwent cadaveric whole liver transplantation. Two years later, he had a metastatic HCC in the superior mediastinum. Over the following postoperative year, he underwent transcatheter arterial chemoembolization (TACE) for 4 tumors in the implanted liver. In the third post-TACE month, he was emergently hospitalized due to intracerebral hematoma with a tumor invading the bone in the medial frontal segment. He underwent emergency intracranial tumorectomy and hemorrhage removal. The histopathologic diagnosis was metastatic HCC. He regained consciousness as well as the ability to speak and to feed himself, resulting in an improved quality of life. The incidence of HCC recurrence after liver transplantation is observed in approximately 8% to 11% of selected cases, with frequent relapses observed in the implanted liver, bones, adrenal glands, and lungs. Mediastinal and intracranial metastases from HCC post-liver transplantation are very rare.

Sumac: a functional food and herbal remedy in traditional herbal medicine in the Asia

2022 ◽  
pp. 261-266
Author(s):  
Mehdi Khoshkharam ◽  
Mohamad Hesam Shahrajabian ◽  
Ram B. Singh ◽  
Wenli Sun ◽  
Anathi Magadlela ◽  
...  
Keyword(s):  
Herbal Medicine ◽  
Functional Food ◽  
Herbal Remedy ◽  
Traditional Herbal Medicine

scholarly journals Effects of Supplemental Chinese Traditional Herbal Medicine Complex on the Carcass Quality of Pigs

2013 ◽  
Vol 1 (2) ◽  
pp. 141
Author(s):  
Hui-Shuang Yeh ◽  
Kou-Joong Lin ◽  
Chun-Kuang Chou ◽  
Tu-Fa Lien ◽  
Chia-Mo Liao
Keyword(s):  
Herbal Medicine ◽  
Meat Quality ◽  
Chinese Herbal Medicine ◽  
Growing Pigs ◽  
Carcass Quality ◽  
Traditional Herbal Medicine ◽  
Beneficial Effects ◽  
Chinese Herbal ◽  
A Value

This study was to investigate the effect of adding Chinese traditional herbal medicine complex in diets on the carcass quality of the pigs. 100 crossbred growing pigs (LYD) (44.5 ± 1.63 kg) were randomly divided into 5 groups including supplementation 0.0, 0.3, 0.5 and 0.7% Chinese herbal medicine complex (CHM), and antibiotics groups (chlortetracycline 100 ppm and oxytetracycline 100 ppm) with four replicates. Experimental results indicated that meat polyphenol and flavonoids content in the group with 0.7% CHM addition, and the Hunter a value in the 0.5% and 0.7% CHM groups was better than those of the control and antibiotics groups (P<0.05). The panel evaluation revealed that the 0.7% CHM supplemented group had better values for juiciness and overall-acceptance than the control and antibiotics groups (P<0.05). In conclusion, supplementation of Chinese herbal medicine complex in pig’s diet had beneficial effects on meat quality, and 0.7% CHM addition had the best results for meat quality.

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