scholarly journals Phytochemical and Pharmacological Review of Da Chuanxiong Formula: A Famous Herb Pair Composed ofChuanxiong RhizomaandGastrodiae Rhizomafor Headache

2013 ◽  
Vol 2013 ◽  
pp. 1-16 ◽  
Author(s):  
Lu Wang ◽  
Jinming Zhang ◽  
Yanlong Hong ◽  
Yi Feng ◽  
Meiwan Chen ◽  
...  

Chronic headache such as migraine and nervous headache has become one of the most common locations of pain and one of the most difficult diseases to recover due to its numerous causes and inconvenience to keep acesodyne administration for a long time. However, there are a series of treatment theories and herbal formulas for this disease in traditional Chinese medicine (TCM), in which Da Chuanxiong formula (DCXF), a herb pair composed ofChuanxiong Rhizoma(CR), Chuanxiong in Chinese, andGastrodiae Rhizoma(GR) called as Tianma in China, is a greatly classic representative. This formula has been used for headaches via dispelling wind pathogen and dissipating blood stasis for many years in TCM. In recent years, the efficiency and representativeness of DCXF have garnered many researchers’ attention. To reveal the compatibility mechanism and develop innovative Chinese herb, herein ethnopharmacological relevance, chemical characters, and pharmacological actions of DCXF are detailed. It is expected to give a comprehensive interpretation of DCXF, namely, Chuanxiong Tianma herb pair (CTHP), to inherit the essence of herb pair and innovate drug delivery system of this prescription.

Drug Delivery ◽  
2014 ◽  
Vol 22 (3) ◽  
pp. 258-265 ◽  
Author(s):  
Wei Xu ◽  
Feng J. Xing ◽  
Kai Dong ◽  
Cuiyu You ◽  
Yan Yan ◽  
...  

2021 ◽  
pp. 95-116
Author(s):  
Xuechun Liu ◽  
Haiyan Hu ◽  
Ziqi Chen ◽  
Zekang Zhang ◽  
Changhai Wang ◽  
...  

2018 ◽  
Vol 46 (08) ◽  
pp. 1791-1824 ◽  
Author(s):  
Lei Li ◽  
Yi Feng ◽  
Yanlong Hong ◽  
Xiao Lin ◽  
Lan Shen

Traditional Chinese Medicine (TCM) has been used in China for thousands of years for the prevention and treatment of various diseases. The materials that exert a therapeutic effect are called the active ingredients. The bioactive glycosides are important active ingredients from TCM that can make significant contributions to treating diseases. Because of the possibilities of various clinical applications, the properties and administration of these bioactive glycosides deserve further investigation. Their promising treatment effects, however, are hindered by their poor solubility, poor stability and rapid elimination. Therefore, it is necessary that we improve the therapeutic efficacy of bioactive glycosides by overcoming these problems. Meanwhile, some practical design strategies and novel drug delivery vehicles based on drug delivery systems provide favorable support in clinical practice for these active ingredients. This review summarizes diverse pharmacological activities of bioactive glycosides and focuses on recent advances in delivery system for these active constitutes; in particular, some glycol glycosides can effectively cure intractable diseases through targeted drug delivery. This review elucidates some design strategies for drug delivery system that are mainly based on two methods (avoiding physical barriers by changing dosage forms and enhancing the ability to bind to receptors or proteins after administration) and indicate the current challenges during the combination of delivery vehicles and these glycosides in hopes of promoting the process of receiving ideal therapeutic efficacy of them in future studies.


2021 ◽  
Vol 2 (1) ◽  
Author(s):  
Siukan Law ◽  
Albert Wingnang Leung ◽  
Chuanshan Xu

Dear Editor, Scutellaria barbata D. Don (SBD) is a perennial herb and belongs to the “Lamiaceae” family. This is widely used in China for a long time as Traditional Chinese Medicine (TCM). Based on the TCM theory, SBD is in the category of “Heat-Clearing”. Its functions are to remove heat and detoxification, disperse blood stasis and diuresis. [...]


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