scholarly journals Traditional Chinese medicine combined with pulmonary drug delivery system and idiopathic pulmonary fibrosis: Rationale and therapeutic potential

2021 ◽  
Vol 133 ◽  
pp. 111072
Author(s):  
Yukun Zhang ◽  
Peng Lu ◽  
Huan Qin ◽  
Yuelin Zhang ◽  
Xinru Sun ◽  
...  
Drug Delivery ◽  
2014 ◽  
Vol 22 (3) ◽  
pp. 258-265 ◽  
Author(s):  
Wei Xu ◽  
Feng J. Xing ◽  
Kai Dong ◽  
Cuiyu You ◽  
Yan Yan ◽  
...  

2021 ◽  
pp. 95-116
Author(s):  
Xuechun Liu ◽  
Haiyan Hu ◽  
Ziqi Chen ◽  
Zekang Zhang ◽  
Changhai Wang ◽  
...  

2018 ◽  
Vol 46 (08) ◽  
pp. 1791-1824 ◽  
Author(s):  
Lei Li ◽  
Yi Feng ◽  
Yanlong Hong ◽  
Xiao Lin ◽  
Lan Shen

Traditional Chinese Medicine (TCM) has been used in China for thousands of years for the prevention and treatment of various diseases. The materials that exert a therapeutic effect are called the active ingredients. The bioactive glycosides are important active ingredients from TCM that can make significant contributions to treating diseases. Because of the possibilities of various clinical applications, the properties and administration of these bioactive glycosides deserve further investigation. Their promising treatment effects, however, are hindered by their poor solubility, poor stability and rapid elimination. Therefore, it is necessary that we improve the therapeutic efficacy of bioactive glycosides by overcoming these problems. Meanwhile, some practical design strategies and novel drug delivery vehicles based on drug delivery systems provide favorable support in clinical practice for these active ingredients. This review summarizes diverse pharmacological activities of bioactive glycosides and focuses on recent advances in delivery system for these active constitutes; in particular, some glycol glycosides can effectively cure intractable diseases through targeted drug delivery. This review elucidates some design strategies for drug delivery system that are mainly based on two methods (avoiding physical barriers by changing dosage forms and enhancing the ability to bind to receptors or proteins after administration) and indicate the current challenges during the combination of delivery vehicles and these glycosides in hopes of promoting the process of receiving ideal therapeutic efficacy of them in future studies.


Author(s):  
Vijay R. Salunkhe ◽  
Prasanna S. Patil ◽  
Ganesh H. Wadkar ◽  
Somnath D. Bhinge

Herbal medicines have tremendous therapeutic potential that can explored across various effective drug delivery system. Decoctions, herbal teas, tinctures, glyceritum, oxymel, and use much soap, herbal tablets, herbal capsules, and herbal cream, herbal books, and prepared the confection of the most commonly available forms of dosage. The less use of herbal formulations in recent decades due to their lack of standardization. It is possible to use plant extract and isolated constituents to overcome this problem. But these phytoconstituents are suffering from drawbacks, mostly due to problems with stability and low lipid solubility. Novel drug delivery such as liposomes plays an important role in problem solving. Infact, compliance with the patient also improves. The review article discusses the recent status of new herbal liposomal formulations and describes the different ways in which these formulations are prepared.


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