scholarly journals Neonatal Natural Killer Cell Function: Relevance to Antiviral Immune Defense

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Yen-Chang Lee ◽  
Syh-Jae Lin

Neonates are particularly susceptible to various pathogens compared to adults, which is attributed in part to their immature innate and adaptive immunity. Natural killer cells provide first-line innate immune reactions against virus-infected cells without prior sensitization. This review updates phenotypic and functional deficiencies of neonatal cells compared to their adult counterparts and their clinical implications.

2015 ◽  
Vol 43 (1) ◽  
Author(s):  
Yen-Chang Lee ◽  
Syh-Jae Lin

AbstractNatural killer (NK) cells that provide first-line innate immune reactions against virus-infected and tumor cells have different roles in different body sites and in different stages. From the beginning of life, NK cells participate in many aspects of development, especially in a successful pregnancy and a healthy neonatal stage. This article reviews recent advances regarding the role of NK cells in implantation, placentation and immune tolerance during pregnancy as well as in the neonatal immune defense. The interactions between NK cells and other immune cells in each developmental stage are discussed.


2021 ◽  
Vol 99 ◽  
pp. 107965
Author(s):  
Liu Yang ◽  
Yuanyuan Feng ◽  
Shanshan Wang ◽  
Shanyue Jiang ◽  
Longxiang Tao ◽  
...  

2012 ◽  
Vol 13 (1) ◽  
pp. 8-14 ◽  
Author(s):  
Syh-Jae Lin ◽  
Dah-Chin Yan ◽  
Wen-I. Lee ◽  
Ming-Ling Kuo ◽  
Hsiu-Shan Hsiao ◽  
...  

2012 ◽  
Vol 21 (8) ◽  
pp. 1333-1343 ◽  
Author(s):  
Olga DelaRosa ◽  
Beatriz Sánchez-Correa ◽  
Sara Morgado ◽  
Cristina Ramírez ◽  
Borja del Río ◽  
...  

Apmis ◽  
1992 ◽  
Vol 100 (1-6) ◽  
pp. 10-20 ◽  
Author(s):  
H. M. ÖGMUNDSDÓTTIR ◽  
L. THORSTEINSSON ◽  
A. SIGFÚSSON ◽  
S. SVEINSDOTTIR ◽  
S. BJÖRNSSON ◽  
...  

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