Neonatal Natural Killer Cell Function: Relevance to Antiviral Immune Defense
2013 ◽
Vol 2013
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pp. 1-6
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Keyword(s):
Neonates are particularly susceptible to various pathogens compared to adults, which is attributed in part to their immature innate and adaptive immunity. Natural killer cells provide first-line innate immune reactions against virus-infected cells without prior sensitization. This review updates phenotypic and functional deficiencies of neonatal cells compared to their adult counterparts and their clinical implications.