scholarly journals Spectrum of Gastroenteropancreatic NENs in Routine Histological Examinations of Bioptic and Surgical Specimen: A Study of 161 Cases Collected from 17 Departments of Pathology in the Czech Republic

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Václav Mandys ◽  
Tomáš Jirásek

Objective.To characterize GEP-NENs in routine biopsies and surgical specimen in the Czech Republic and to evaluate how WHO Classification (2010) is acceptable in diagnostic practice.Methods.Paraffin-embedded blocks and bioptic reports were collected from 17 departments of pathology. Histologic slides were stained with H&E and immunohistologically for CgA, synaptophysin, and Ki-67.Results.Out of 28 gastric NENs, there were 22 NETs, G1, 5 NETs, G2, and 1 NEC. Ten duodenal NENs were NETs, G1. Among 27 NENs of jejunum and ileum, 23 were NETs, G1, 2 NETs, G2, and 1 NEC and 1 mixed adenoneuroendocrine carcinoma (MANEC). Among 42 appendiceal “incidentalomas”, 39 were NETs G1, 2 goblet cell carcinoids, and 1 MANEC. Out of 34 large intestinal NENs, 30 were NETs, G1, 3 NETs, G2, and 1 NEC. One small intestinal and 6 large bowel neoplasms were reclassified as poorly differentiated adenocarcinomas. In 12 pancreatic NENs, there were 7 NETs, G1, 3 NETs, G2, and 2 NECs.Conclusions.Our study demonstrates differences in GEP-NENs frequency in sites of origin in our region, comparing to other countries. Regarding routine bioptic diagnostics, we gave evidence that the WHO 2010 classification of NENs is fully acceptable for exact categorisation of tumours.

Author(s):  
Jana Niedobová ◽  
Vladimír Hula ◽  
Pavla Šťastná

Collecting of Carabidae was conducted using pitfall traps at four sites. The first two sites (T1 + T2) were at the slope of Macošská stráň and the other two sites (T3 + T4) at the slope of Vilémovická stráň. The study was done in 2008 and 2009. At Macošská stráň in 2008, 21 species of Carabidae with the total number of 228 individuals were found and in 2009, 18 species of the total number of 116 specimens were collected. At Vilémovická stráň in 2008, 22 species of Carabidae with the total number of 1977 specimens were found and in 2009, 21 species of the total number of 623 specimens were caught. In terms of classification of relictness, Macošská stráň in 2008 was dominated by species of adaptable group A (60%), species of eurytop group (E) were represented by 35% and of relic group (R) by 5%. In 2009, the same representation of species of groups A and E (47%) were found and the species of group R were represented by 6%. Vilémovická stráň in 2008 was dominated by species of group A (52%), species of group E were represented by 43% and of group R by 5%. In 2009 also dominated species of group A (54%), species of group E were represented by 41% and of group R by 5%. In the studied area we reported four endangered species of Carabidae protected by Law (No. 395/1992 Coll.) as amended, these were Calosoma auropunctatum (critically endangered), Brachinus crepitans, Carabus ullrichii and Cicindela campestris (endangered) and two species listed under the Red List of Threatened Species of the Czech Republic (Veselý et al., 2005). One of the species is listed as vulnerable (Calosoma auropunctatum) and one as near endangered (Carabus cancellatus). Another significant species found on the monitored sites was Aptinus bombarda.


Author(s):  
Jarmila Šebestová ◽  
Zuzana Palová

The aim of this chapter is to summarize the theoretical knowledge from the field of social entrepreneurship and the creation of social innovation and highlight the impact EU funds have on the development of social innovation in selected regions of the Czech Republic. The authors assumed that there could be a positive link between the amount of financial support and the number of created social innovations within the chosen EU programmes. Classification of created social innovation according to type, creator, priority axis in relation to beneficiary etc. came under other objectives. Social innovations are created as a positive externality from other social projects. Finally, recommendation for sustainable support evaluation is provided.


2012 ◽  
Vol 51 (No. 10) ◽  
pp. 435-451 ◽  
Author(s):  
F. Střeleček ◽  
J. Lososová

ThearticledescribesthelayoutofplantproductionandlivestockdensityintheCzechRepublicin2003 according to a sample survey of the Czech Statistical Office.Theproductionorientationof agriculturalenterprisesis definedas a small amount of market products that represent the predominant part of revenues. Grain crops, pork meat, milk and non-food crops represent the production orientation of Czech agriculture. Thesecommoditiesrepresentmorethan70%oftotal agricultural production in the Czech Republic. In this article, the authors have attempted to definearegionalclassification according to production orientation of agricultural enterprises and intensity of agricultural production.


2012 ◽  
Vol 58 (No. 4) ◽  
pp. 191-199 ◽  
Author(s):  
P. Kment ◽  
L. Kocmánková

An increasing number of works on the rural-environmental connection can be found at present. However, their overview and classification are needed – this is the guiding idea of this paper. We distinguish three approaches to the rural-environmental connection and label them scientific approach, environmentalist approach, and development approach. In the paper, theories of environmental concern (post-materialism, paradigm shift, and ecological modernisation) are discussed at first and then a classification of works is proposed.  


Geografie ◽  
2004 ◽  
Vol 109 (2) ◽  
pp. 117-128
Author(s):  
Bohumír Janský ◽  
Miroslav Šobr

The paper provides genetic classification of lakes in the Czech Republic. We separate lakes to two groups - natural and anthropogenic origin. The genetic classification is based on the classification of lakes according to the way of origination of the lake basin while the geomorphologic viewpoint prevails: glacial lakes, fluvial lakes, karst lakes, lakes dammed-up by landslides, organogenous lakes and anthropogenic lakes. As the anthropogenic lakes we may regard all the water bodies which originated as a consequence of the human activity - mining of mineral resources.


2016 ◽  
Vol 24 (1) ◽  
pp. 53-78
Author(s):  
Tomáš Weiss

The article proposes a classification of interest promotion methods used by small EU member states which draws on lobbying literature in order for us to better understand how small states pursue their preferences in Council negotiations. It explores a single case study of the Czech Republic's efforts to influence the 2012 revision of the European Union's Generalised System of Preferences scheme through the lenses of this classification. The empirical part of the paper is based on original research interviews with European and Czech stakeholders who participated in the studied negotiations. While the dossier was considered important, the Czech Republic failed to employ more elaborate methods of interest promotion and thus came away with a sub-optimal outcome. Rather than explaining this by pointing to a lack of socialization of Czech representatives (and thus a lack of effective competence), this deficiency can be better explained by the low salience of the general policy area for the Czech Republic, which prevented the country from developing a favourable position from which to react promptly to the related developments and deploy the lobbying tools at its disposal. The article suggests that the lobbyist-like character of a small member state's performance in the Council may have wider consequences for the flexibility of the country's EU policy and the ability of its governments to pursue specific European policies.


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