scholarly journals Intrauterine Growth Retardation Fetus with Trisomy 16 Mosaicism

2014 ◽  
Vol 2014 ◽  
pp. 1-3 ◽  
Author(s):  
Takol Chareonsirisuthigul ◽  
Suchin Worawichawong ◽  
Rachanee Parinayok ◽  
Patama Promsonthi ◽  
Budsaba Rerkamnuaychoke
Keyword(s):  
Growth Retardation ◽  
Intrauterine Growth Retardation ◽  
Fetal Heart ◽  
Cytogenetic Study ◽  
Normal Karyotype ◽  
Internal Organs ◽  
Normal Morphology ◽  
Trisomy 16 ◽  
Intrauterine Growth ◽  
Mosaic Trisomy

Fetal trisomy 16 is considered uniformly lethal early in gestation. It has been reported to be associated with the variability of clinical features and outcomes. Mosaic trisomy 16 leads to a high risk of abnormality in prenatal cases. Intrauterine growth retardation (IUGR) is a common outcome of mosaic trisomy 16. Herein, we report on the case of Thai male IUGR fetus with trisomy 16 mosaicism. The fetal body was too small. Postmortem investigation of placenta revealed the abnormality including small placenta with furcated cord insertion and single umbilical cord artery. Cytogenetic study demonstrated trisomy 16 that was found 100% in placenta and only 16% in the fetal heart while other organs had normal karyotype. In addition, cardiac and other internal organs examination revealed normal morphology.

Imbalance in the system L-arginin-NO in pathogenesis of obstetric complications and intrauterine growth retardation (Literature review)

2016 ◽  
pp. 43-47
Author(s):  
O.V. Basystyi ◽  
Keyword(s):  
Nitric Oxide ◽  
Literature Review ◽  
Growth Retardation ◽  
Intrauterine Growth Retardation ◽  
Obstetric Complications ◽  
Pathogenetic Role ◽  
Intrauterine Growth ◽  
System L ◽  
Nitric Oxide Deficiency

The data of domestic and foreign literature on etiology, pathogenesis and intrauterine growth retardation diagnosis are presented in the paper. It highlights pathogenetic role of nitric oxide deficiency in case of obstetric complications and intrauterine growth retardation. Key words: intrauterine growth retardation (IUGR), system L-arginin–NO, obstetric complications.

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