scholarly journals Protocol for Bone Augmentation with Simultaneous Early Implant Placement: A Retrospective Multicenter Clinical Study

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Peter Fairbairn ◽  
Minas Leventis
Keyword(s):  
Bone Regeneration ◽  
Alveolar Bone ◽  
Functional Results ◽  
Treatment Modalities ◽  
Specific Method ◽  
Bone Augmentation ◽  
Implant Placement ◽  
Alloplastic Materials ◽  
One Year ◽  
Atraumatic Extraction

Purpose.To present a novel protocol for alveolar bone regeneration in parallel to early implant placement.Methods.497 patients in need of extraction and early implant placement with simultaneous bone augmentation were treated in a period of 10 years. In all patients the same specific method was followed and grafting was performed utilizingin situhardening fully resorbable alloplastic grafting materials consisting ofβ-tricalcium phosphate and calcium sulfate. The protocol involved atraumatic extraction, implant placement after 4 weeks with simultaneous bone augmentation, and loading of the implant 12 weeks after placement and grafting. Follow-up periods ranged from 6 months to 10 years (mean of 4 years).Results.A total of 601 postextraction sites were rehabilitated in 497 patients utilizing the novel protocol. Three implants failed before loading and three implants failed one year after loading, leaving an overall survival rate of99.0%.Conclusions.This standardized protocol allows successful long-term functional results regarding alveolar bone regeneration and implant rehabilitation. The concept of placing the implant 4 weeks after extraction, augmenting the bone around the implant utilizing fully resorbable, biomechanically stable, alloplastic materials, and loading the implant at 12 weeks seems to offer advantages when compared with traditional treatment modalities.

scholarly journals Horizontal Bone Augmentation and Simultaneous Implant Placement using Xenogeneic Bone Rings Technique: A Retrospective Clinical Study

2020 ◽  
Author(s):  
Yude Ding ◽  
LianFei Wang ◽  
Kuiwei Su ◽  
Jinxing Gao ◽  
Xiao Li ◽  
...  
Keyword(s):  
Alveolar Bone ◽  
Survival Rates ◽  
Bone Grafts ◽  
Bone Defects ◽  
Bone Augmentation ◽  
Implant Placement ◽  
Retrospective Clinical Study ◽  
One Year ◽  
The One

Abstract Objectives: This study evaluated the use of bone ring technique with xenogeneic bone grafts in treating horizontal alveolar bone defects. Material and methods: In total, 11 patients in need of horizontal bone augmentation treatment before implant placement were included in this retrospective study. All patients received simultaneous bone augmentation surgery and implant placement with xenogeneic bone ring grafts. We evaluated the postoperative efficacy of the bone ring technique with xenogeneic bone grafts using radiographical and clinical parameters. Results: Survival rates of implants were 100%. Cone-beam computed tomography revealed that the xenogeneic bone ring graft had significantly sufficient horizontal bone augmentation below the implant neck platform to 0 mm, 1mm, 2mm, and 3mm. It could also provide an excellent peri-implant tissue condition during the one-year follow-up after loading. Conclusion: The bone ring technique with xenogeneic bone ring graft could increase and maintain horizontal bone mass in the region of the implant neck platforms in serious horizontal bone defects.

scholarly journals Bone Regeneration Using a Three-Dimensional Hexahedron Channeled BCP Block Combined with Bone Morphogenic Protein-2 in Rat Calvarial Defects

Materials ◽  
2019 ◽  
Vol 12 (15) ◽  
pp. 2435 ◽  
Author(s):  
So-Yeun Kim ◽  
Eun-Bin Bae ◽  
Jae-Woong Huh ◽  
Jong-Ju Ahn ◽  
Hyun-Young Bae ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Alveolar Bone ◽  
Three Dimensional ◽  
Bone Morphogenetic Protein 2 ◽  
Graft Material ◽  
Implant Placement ◽  
Morphogenetic Protein ◽  
Human Bone Morphogenetic Protein ◽  
Calvarial Defects ◽  
Rat Calvarial Defect

It is important to obtain sufficient bone mass before implant placement on alveolar bone, and synthetic bone such as biphasic calcium phosphate (BCP) has been studied to secure this. This study used a BCP block bone with a specific structure of the three-dimensional (3D) hexahedron channel and coating with recombinant human bone morphogenetic protein-2 (rhBMP-2) impregnated carboxymethyl cellulose (CMC) was used to examine the enhancement of bone regeneration of this biomaterial in rat calvarial defect. After the preparation of critical-size calvarial defects in fifteen rats, defects were divided into three groups and were implanted with the assigned specimen (n = 5): Boneplant (untreated 3D hexahedron channeled BCP block), Boneplant/CMC (3D hexahedron channeled BCP block coated with CMC), and Boneplant/CMC/BMP (3D hexahedron channeled BCP block coated with CMC containing rhBMP-2). After 4 weeks, the volumetric, histologic, and histometric analyses were conducted to measure the newly formed bone. Histologically, defects in the Boneplant/CMC/BMP group were almost completely filled with new bone compared to the Boneplant and Boneplant/CMC groups. The new bone volume (P < 0.05) and area (P < 0.001) in the Boneplant/CMC/BMP group (20.12% ± 2.17, 33.79% ± 3.66) were much greater than those in the Boneplant (10.77% ± 4.8, 16.48% ± 9.11) and Boneplant/CMC (10.72% ± 3.29, 16.57% ± 8.94) groups, respectively. In conclusion, the 3D hexahedron channeled BCP block adapted rhBMP-2 with carrier CMC showed high possibility as an effective bone graft material.

scholarly journals Efficacy of Bacterial Cellulose as a Carrier of BMP-2 for Bone Regeneration in a Rabbit Frontal Sinus Model

Materials ◽  
2019 ◽  
Vol 12 (15) ◽  
pp. 2489 ◽  
Author(s):  
Takashi Koike ◽  
Jingjing Sha ◽  
Yunpeng Bai ◽  
Yuhei Matsuda ◽  
Katsumi Hideshima ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Bacterial Cellulose ◽  
Alveolar Bone ◽  
Dental Treatment ◽  
Bone Morphogenetic Protein 2 ◽  
Nuclear Antigen ◽  
Bone Augmentation ◽  
Morphogenetic Protein ◽  
Maxillary Molar ◽  
Proliferating Cell

If the alveolar bone height of patients requiring dental implants in the maxillary molar region is inadequate, it is difficult to achieve satisfactory outcomes using existing bone graft materials. We previously reported the possible utility of bacterial cellulose (BC) as a new dental treatment material. BC has a high absorptive capacity, good mechanical strength, and good volume retention. BC loaded with bone morphogenetic protein-2 (BMP-2) might allow effective alveolar bone augmentation. We created critical frontal bone defect models in 12 male Japanese white rabbits and divided them into four groups: sham; BC (BC grafting only); BMP-2 (treated with BMP-2 solution only); and BC+BMP-2 (grafted with BC loaded with BMP-2). Newly formed bone volume was calculated via hematoxylin-eosin staining evaluation. The proliferating cell nuclear antigen and osteocalcin levels were determined by the immunohistochemical staining analysis. All measured indices of the BC+BMP-2 group were significantly superior to those of the other groups (all p < 0.05). BC maintained the graft space and released BMP-2 in a sustained manner, promoting optimal bone formation. The BC+BMP-2 combination enhanced bone regeneration and shows promise as a useful means of clinical pre-dental implant bone augmentation in the maxillary sinus.

Efficacy of Alveolar Ridge Preservation: A Randomized Controlled Trial

2020 ◽  
Vol 99 (4) ◽  
pp. 402-409 ◽  
Author(s):  
G. Avila-Ortiz ◽  
M. Gubler ◽  
M. Romero-Bustillos ◽  
C.L. Nicholas ◽  
M.B. Zimmerman ◽  
...  
Keyword(s):  
Tooth Extraction ◽  
Alveolar Bone ◽  
Controlled Trial ◽  
Control Group ◽  
Ridge Preservation ◽  
Alveolar Ridge ◽  
Bone Augmentation ◽  
Randomized Controlled ◽  
Implant Placement ◽  
Alveolar Ridge Preservation

Alveolar ridge preservation (ARP) therapy is indicated to attenuate the physiologic resorptive events that occur as a consequence of tooth extraction with the purpose of facilitating tooth replacement therapy. This randomized controlled trial was primarily aimed at testing the efficacy of ARP as compared with unassisted socket healing. A secondary objective was to evaluate the effect that local phenotypic factors play in the volumetric reduction of the alveolar bone. A total of 53 subjects completed the study. Subjects were randomized into either the control group, which involved only tooth extraction (EXT n = 27), or the experimental group, which received ARP using a combination of socket grafting with a particulate bone allograft and socket sealing with a nonabsorbable membrane (dPTFE) following tooth extraction (ARP n = 26). A set of clinical, linear, volumetric, implant-related, and patient-reported outcomes were assessed during a 14-wk healing period. All linear bone assessments (horizontal, midbuccal, and midlingual reduction) revealed that ARP is superior to EXT. Likewise, volumetric bone resorption was significantly higher in the control group (mean ± SD: EXT = −15.83% ± 4.48%, ARP = −8.36% ± 3.81%, P < 0.0001). Linear regression analyses revealed that baseline buccal bone thickness is a strong predictor of alveolar bone resorption in both groups. Interestingly, no significant differences in terms of soft tissue contour change were observed between groups. Additional bone augmentation to facilitate implant placement in a prosthetically acceptable position was deemed necessary in 48.1% of the EXT sites and only 11.5% of the ARP sites ( P < 0.004). Assessment of perceived postoperative discomfort at each follow-up visit revealed a progressive decrease over time, which was comparable between groups. Although some extent of alveolar ridge remodeling occurred in both groups, ARP therapy was superior to EXT as it was more efficacious in the maintenance of alveolar bone and reduced the estimated need for additional bone augmentation at the time of implant placement (ClinicalTrials.gov NCT01794806).

scholarly journals Alveolar Bone Regeneration for Immediate Implant Placement Using an Injectable Bone Substitute: An Experimental Study in Dogs

2004 ◽  
Vol 75 (5) ◽  
pp. 663-671 ◽  
Author(s):  
Damien Boix ◽  
Olivier Gauthier ◽  
Jérôme Guicheux ◽  
Paul Pilet ◽  
Pierre Weiss ◽  
...  
Keyword(s):  
Experimental Study ◽  
Bone Regeneration ◽  
Bone Substitute ◽  
Alveolar Bone ◽  
Implant Placement ◽  
Immediate Implant

scholarly journals Sandwich Bone Augmentation (SBA) in immediate implant placement post dentoalveolar trauma: a case report

2017 ◽  
Vol 2 (3) ◽  
pp. 197
Author(s):  
Anton Anton ◽  
Poerwati S. Rahajoe ◽  
Bambang Dwirahardjo
Keyword(s):  
Bone Defect ◽  
Stable Condition ◽  
Bone Augmentation ◽  
Titanium Mesh ◽  
Bone Thickness ◽  
Implant Placement ◽  
Immediate Implant ◽  
Dentoalveolar Trauma ◽  
One Year ◽  
Ti Mesh

Objective: Reporting the application of SBA procedure with titanium mesh as an alternative solution for immediate implant placement in socket with dentoalveolar trauma-induced buccal bone defect.Methods: An 18-year-old female patient visited our department, with a history dentoalveolar trauma and a loss of  tooth 21. Clinical examination during the implant placement procedure exposed  a socket with buccal bone defect. SBA with autogenous chin bone graft combined with DFDBA allograft and stabilized with titanium mesh (Ti-Mesh) for buccal defect on which flap reposition was done with tension free primary closure.Results: Ti-Mesh was removed after 3 months which no sign of inflamation appeared, implant was in a stable condition and new bone formation was observed. Subsequently, healing abutment was placed. A one-year observation suggested a good clinical retention with no luxation observed, along with decent functional and esthetic results. CBCT evaluation showed buccal bone thickness preserved.Conclusion: Sandwich bone augmentation with stabilized titanium mesh provides a satisfying result in treating horizontal buccal bone defect.

scholarly journals Guided Bone Regeneration- A Comprehensive Review

2021 ◽  
Author(s):  
Vineetha Venugopalan ◽  
Anegundi Raghavendra Vamsi ◽  
Santhosh Shenoy ◽  
Karishma Ashok ◽  
Biju Thomas
Keyword(s):  
Bone Regeneration ◽  
Alveolar Bone ◽  
Primary Stability ◽  
Guided Bone Regeneration ◽  
Collagen Membrane ◽  
Bony Defect ◽  
Graft Material ◽  
Bone Augmentation ◽  
Wide Range ◽  
Space Maintenance

Successful implant treatment requires prosthetically driven placement of an implant, primary stability at placement, and careful living bone management. The resorptive changes of alveolar bone are an inevitable process following tooth loss, periodontal disease or trauma which causes bone defects. This results in various aesthetic and functional complications such as soft tissue recession, infection and inflammation. Various methods have been tried and advocated for augmenting these bone deficiencies. Guided Bone Regeneration (GBR) is a successful modality for bone augmentation with a wide range of indications and helps restore the alveolar ridge dimensions. It utilises the principle of Guided Tissue Regeneration (GTR) for space maintenance within a bony defect. Different types of barrier membranes are being utilised along with various bone grafts in GBR. Thorough knowledge regarding the biology of bone is required before the initiation of any bone augmentation procedure. A combination of Collagen Membrane (CM) and graft material was found successful for GBR. Hence, this review focuses on presentation of best available evidence for various aspects of GBR.

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