scholarly journals Guided Bone Regeneration- A Comprehensive Review

2021 ◽  
Author(s):  
Vineetha Venugopalan ◽  
Anegundi Raghavendra Vamsi ◽  
Santhosh Shenoy ◽  
Karishma Ashok ◽  
Biju Thomas
Keyword(s):  
Bone Regeneration ◽  
Alveolar Bone ◽  
Primary Stability ◽  
Guided Bone Regeneration ◽  
Collagen Membrane ◽  
Bony Defect ◽  
Graft Material ◽  
Bone Augmentation ◽  
Wide Range ◽  
Space Maintenance

Successful implant treatment requires prosthetically driven placement of an implant, primary stability at placement, and careful living bone management. The resorptive changes of alveolar bone are an inevitable process following tooth loss, periodontal disease or trauma which causes bone defects. This results in various aesthetic and functional complications such as soft tissue recession, infection and inflammation. Various methods have been tried and advocated for augmenting these bone deficiencies. Guided Bone Regeneration (GBR) is a successful modality for bone augmentation with a wide range of indications and helps restore the alveolar ridge dimensions. It utilises the principle of Guided Tissue Regeneration (GTR) for space maintenance within a bony defect. Different types of barrier membranes are being utilised along with various bone grafts in GBR. Thorough knowledge regarding the biology of bone is required before the initiation of any bone augmentation procedure. A combination of Collagen Membrane (CM) and graft material was found successful for GBR. Hence, this review focuses on presentation of best available evidence for various aspects of GBR.

scholarly journals D-Ptfe Cytoplast® membranes in guided bone regeneration in implantology

2020 ◽  
pp. 108-135
Author(s):  
Renato Brandi Pereira Carneiro ◽  
Flávio de Ávila Kfouri
Keyword(s):  
Literature Review ◽  
Bone Quality ◽  
Guided Bone Regeneration ◽  
Graft Material ◽  
Bone Augmentation ◽  
Ptfe Membrane ◽  
Oral Environment ◽  
Bacterial Penetration ◽  
Space Maintenance ◽  
Bone Gain

The vertical bone increase of alveolar rim is important to obtain good results in rehabilitation with prostheses on implants. This Literature Review sought articles that treat bone increases of alveolar edges using Cytoplast® membranes, seeking to evaluate the resistance to bacterial penetration and capacity to create and maintain space. For this, a literature review was made on the Pubmed and Google scholar search platforms. The researches analyzed found similar results between d-PTFE membrane, titanium meshes and e-PTFE membranes, both in bone gain and bone quality. The space maintenance capacity was evident in the articles in which the titanium reinforced membrane was used. The d-PTFE membrane presented a greater capacity of exposure to the oral environment without compromising the graft material. The authors researched in this study found that titanium-reinforced d-PTFE membranes for bone augamble alveolar rim increases are viable and allow a certain period of exposure to the oral environment without graft contamination. Further studies are needed with the Cytoplast® d-PTFE membrane to explore its characteristics with vertical bone augmentation procedures.

scholarly journals Aligned Nanofiber-Guided Bone Regeneration Barrier Incorporated with Equine Bone-Derived Hydroxyapatite for Alveolar Bone Regeneration

Polymers ◽  
2020 ◽  
Vol 13 (1) ◽  
pp. 60
Author(s):  
Jae Woon Lim ◽  
Kyoung-Je Jang ◽  
Hyunmok Son ◽  
Sangbae Park ◽  
Jae Eun Kim ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Bone Tissue ◽  
High Speed ◽  
Alveolar Bone ◽  
Guided Bone Regeneration ◽  
Bone Tissue Regeneration ◽  
Calcium Deposition ◽  
Graft Material ◽  
Post Surgery ◽  
Equine Bone

Post-surgery failure of dental implants due to alveolar bone loss is currently critical, disturbing the quality of life of senior dental patients. To overcome this problem, bioceramic or bone graft material is loaded into the defect. However, connective tissue invasion instead of osteogenic tissue limits bone tissue regeneration. The guided bone regeneration concept was adapted to solve this problem and still has room for improvements, such as biochemical similarity or oriented structure. In this article, an aligned electrospun-guided bone regeneration barrier with xenograft equine bone-derived nano hydroxyapatite (EBNH-RB) was fabricated by electrospinning EBNH/PCL solution on high-speed rotating drum collector and fiber characterization, viability and differentiation enhancing properties of mesenchymal dental pulp stem cell on the barrier was determined. EBNH-RB showed biochemical and structural similarity to natural bone tissue electron microscopy image analysis and x-ray diffractometer analysis, and had a significantly better effect in promoting osteogenesis based on the increased bioceramic content by promoting cell viability, calcium deposition and osteogenic marker expression, suggesting that they can be successfully applied to regenerate alveolar bone as a guided bone regeneration barrier.

scholarly journals Guided bone regeneration in staged vertical and horizontal bone augmentation using platelet-rich fibrin associated with bone grafts: a retrospective clinical study

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Carlos Alberto Amaral Valladão ◽  
Mabelle Freitas Monteiro ◽  
Julio Cesar Joly
Keyword(s):  
Bone Regeneration ◽  
Bone Grafts ◽  
Bone Defects ◽  
Guided Bone Regeneration ◽  
Collagen Membrane ◽  
Bone Augmentation ◽  
Platelet Rich Fibrin ◽  
Link Type ◽  
Retrospective Clinical Study ◽  
Bone Gain

Abstract Background The use of guided bone regeneration (GBR) for vertical and horizontal bone gain is a predictable approach to correct the bone defects before implant installation; however, the use of different protocols is associated with different clinical results. It is suggested that platelet-rich fibrin (PRF) could improve the outcomes of regenerative procedures. Thus, this study aimed to describe the bone gain associated with GBR procedures combining membranes, bone grafts, and PRF for vertical and horizontal bone augmentation. Materials and methods Eighteen patients who needed vertical or horizontal bone regeneration before installing dental implants were included in the study. The horizontal bone defects were treated with a GBR protocol that includes the use of a mixture of particulate autogenous and xenogenous grafts in the proportion of 1:1, injectable form of PRF (i-PRF) to agglutinate the graft, an absorbable collagen membrane covering the regenerated region, and leukocyte PRF (L-PRF) membrane covering the GBR membrane. The vertical bone defects were treated with the same grafted mixture protected by a titanium-reinforced non-resorbable high-density polytetrafluoroethylene (d-PTFE-Ti) membrane and covered by L-PRF. The bone gain was measured using a cone-beam computed tomography at baseline and after a period of 7.5 (± 1.0) months. Results All patients underwent surgery to install implants after this regenerative protocol. The GBR produces an increase in bone thickness (p < 0.001) and height (p < 0.005) after treatment, with a bone gain of 5.9 ± 2.4 for horizontal defects and 5.6 ± 2.6 for vertical defects. In horizontal defects, the gain was higher in the maxilla than in mandible (p = 0.014) and in anterior than the posterior region (p = 0.033). No differences related to GBR location were observed in vertical defects (p > 0.05). Conclusion GBR associated with a mixture of particulate autogenous and xenogenous grafts and i-PRF is effective for vertical and horizontal bone augmentation in maxillary and mandibular regions, permitting sufficient bone gain to future implant placement. Trial registration REBEC, RBR-3CSG3J. Date of registration—19 July 2019, retrospectively registered. http://www.ensaiosclinicos.gov.br/rg/RBR-3csg3j/

scholarly journals Use of a Partial-thickness Flap for Guided Bone Regeneration in the Upper Jaw

2017 ◽  
Vol 18 (12) ◽  
pp. 1117-1121 ◽  
Author(s):  
Alberto Busa ◽  
Gianluigi Caccianiga
Keyword(s):  
Bone Regeneration ◽  
Surgical Techniques ◽  
Guided Bone Regeneration ◽  
Vascular Supply ◽  
Healing Time ◽  
Collagen Membrane ◽  
Graft Material ◽  
Implant Placement ◽  
Partial Thickness ◽  
Upper Jaw

ABSTRACT Introduction Guided bone regeneration (GBR) aims to restore adequate bone volume for the placement of implants in an ideal location. In this article, we analyze different surgical techniques for tissue management during GBR and a modified partialthickness surgical approach. Materials and methods In a year's time span, five patients were enrolled in the study: Four women and one man (aged 44–59 years). In four patients, a GBR with simultaneous implant placement was adopted, whereas in another patient, a delayed implant placement was done. The flap was of full thickness and overturned on the side palatal with the aim of a retractor, thus exposing the bone crest. The graft material was covered and protected with a resorbable collagen membrane (Geistlich Bio- Gide®, Switzerland). The periosteal layer of the flap was then positioned above the resorbable membrane without traction. The sutures as vertical mattress were then positioned. Each patient received an intramuscular betamethasone dose (4 mg/50 kg) and antibiotic therapy for 7 days (amoxicillin + clavulanic acid 1 gm every 12 hours) and was instructed to maintain oral hygiene and appropriate wound cleaning. The patients were recalled at different times to monitor the healing. Results No cases of tissue dehiscence were observed during the period of wound healing. One patient, however, showed a delayed exposure 4 months after surgery. This occurrence was managed without complications for the patient. Conclusion The design of proposed flap seems to be effective in controlling the risk of dehiscence during the healing time in the GBR. The vascular supply was rarely compromised. The results we obtained are encouraging even if further studies on this technique are needed. Clinical significance Lateral partial-thickness flaps seem to be effective in controlling tissue tension and consequently the risk of dehiscence. The incision vestibularly performed should favor the soft tissue healing. How to cite this article Porcaro G, Busa A, Bianco E, Caccianiga G, Maddalone M. Use of a Partial-thickness Flap for Guided Bone Regeneration in the Upper Jaw. J Contemp Dent Pract 2017;18(12):1117-1121.

scholarly journals Clinical outcomes of peri-implantitis treated with bone substitute and resorbable membrane: a literature review with a systematic approach

2019 ◽  
Vol 67 ◽  
Author(s):  
Letícia Fernandes ALVES ◽  
Poliana Mendes DUARTE ◽  
Elizabeth Ferreira MARTINEZ ◽  
Marcelo Henrique NAPIMOGA ◽  
Marcelo SPERANDIO ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Meta Analysis ◽  
Evaluation Criteria ◽  
Guided Bone Regeneration ◽  
Cochrane Library ◽  
Collagen Membrane ◽  
Bony Defect ◽  
Probing Depth ◽  
The Cochrane Library

ABSTRACT Objective: The objective of this review was to evaluate the outcomes of the treatment of peri-implant defects, using Guided Bone Regeneration. Methods: A literature search was performed based on the PICO methodology in the PubMed/Medline, SciELO, Lilacs electronic databases, CAPES periodicals and the Cochrane Library. We included studies using bovine mineral matrix, associated to a collagen membrane for the treatment of peri-implantitis by Guided Bone Regeneration. Results: Of 1,163 studies, 10 were included in this review after applying the evaluation criteria. A total of 269 implants were treated in 260 patients. The follow-up period ranged from 6 to 48 months. The studies evaluated outcome in terms of reduction in probing depth, gain of clinical attachment and healing of the bony defect. Due to the heterogeneity of the studies, it was not possible to perform meta-analysis. Conclusion: Treatment of peri-implant lesions with Guided Bone Regeneration is a viable modality of treatment, providing reduction in bleeding on probing, as well as gain of clinical attachment. Complete filling of the defect is, however, an unpredictable result.

A Synthetic Biodegradable Polymer Membrane for Guided Bone Regeneration in Bone Defect

2021 ◽  
Vol 17 (3) ◽  
pp. 456-465
Author(s):  
Kangjie Ma ◽  
Dongmei Mei ◽  
Xiaodong Lin ◽  
Li Zhang ◽  
Jie Gao ◽  
...  
Keyword(s):  
Mechanical Strength ◽  
Bone Regeneration ◽  
Polylactic Acid ◽  
Bone Defect ◽  
Biodegradable Polymer ◽  
Alveolar Bone ◽  
Guided Bone Regeneration ◽  
Collagen Membrane ◽  
Gbr Membrane ◽  
Alveolar Bone Defect

Guided bone regeneration (GBR) technique is most commonly used to treat alveolar bone defect. Polylactic acid (PLA) attracts much attention to utilize as a GBR membrane because it has relatively high mechanical strength and biodegradability. However, randomized controlled trials of PLA as a GBR membrane in animals were rare. The aim of this work is to observe the efficacy of polylactic acid membrane in guiding bone regeneration in Beagle canine alveolar bone defect restoration and to compare efficacy with the collagen membrane, providing an experimental basis for further clinical use of the polylactic acid membrane. The tests of physical and chemical properties showed that the PLA membrane has well mechanical strength to maintenance the space for the new bone, and has proper aperture for the attachment of osteoblasts. Through X-ray and histopathological examination of the different time points, the bone grafting material covered with PLA membrane can form similar mature bone compared to collagen membrane ones. Meanwhile, biodegradable speed of the PLA membrane was slower. Thus, this study showed that polylactic acid membrane as synthetic biodegradable polymer was reliably effective in guiding bone regeneration of alveolar bone defects, showed the favorable osteogenic capability and forecasts well applications in bone augmentation.

scholarly journals Bone Augmentation Procedures in Implantology

2021 ◽  
pp. 407-426
Author(s):  
Vinay V. Kumar ◽  
Supriya Ebenezer ◽  
Andreas Thor
Keyword(s):  
Bone Regeneration ◽  
Bone Grafting ◽  
Alveolar Bone ◽  
Three Dimensional ◽  
Guided Bone Regeneration ◽  
Bone Augmentation ◽  
Sinus Floor Elevation ◽  
Sinus Floor ◽  
Implant Dentistry ◽  
Edentulous Jaws

AbstractSuccessful implant dentistry mandates implants to be placed in an appropriate three-dimensional manner that supports the prosthesis adequately. Due to the resorption patterns of edentulous jaws, the ideal position of implants required varying amounts of bone augmentation. Commonly carried out bone-augmentation procedures are Guided Bone Regeneration, onlay bone grafting and sinus floor elevation. This chapter discusses the resorption pattern of edentulous jaws, the biology of alveolar bone of relevance to the maxillofacial surgeon, the biomaterials used for augmentation and the commonly carried out augmentation procedures.

scholarly journals Guided bone regeneration at bony defect using familial tooth graft material: Case report

2012 ◽  
Vol 36 (1) ◽  
pp. 69-73 ◽  
Author(s):  
마득현 ◽  
오지수 ◽  
김승희 ◽  
정미애 ◽  
김정선 ◽  
...  
Keyword(s):  
Case Report ◽  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
Bony Defect ◽  
Graft Material
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