scholarly journals Acute Hemoperitoneum after Administration of Prostaglandin E2for Induction of Labour

2015 ◽  
Vol 2015 ◽  
pp. 1-3
Author(s):  
Zhenyu Zhang ◽  
Jiangyan Lou
Keyword(s):  
Laparoscopic Surgery ◽  
Pregnant Woman ◽  
Pregnant Women ◽  
Stage Iv ◽  
Induction Of Labour ◽  
Cervical Ripening ◽  
Prostaglandin E ◽  
History Of

Prostaglandin E2is widely used in obstetrics and is thought to be relatively safe for cervical ripening and induction of labour. Here we present a case in which acute hemoperitoneum was observed after administration of prostaglandin E2in a pregnant woman. The patient had a history of endometriosis, and a severe pelvic adhesion (ASRM stage IV) was found during her last laparoscopic surgery 3 years previously. In cases with endometriosis, use of prostaglandin E2for induction of labour in pregnant women must be done cautiously.

scholarly journals Oral Versus Vaginal Misoprostol for Induction of Labour

1970 ◽  
Vol 24 (2) ◽  
pp. 44-49 ◽  
Author(s):  
N Sultana ◽  
S Rouf ◽  
M Rashid
Keyword(s):  
Pregnant Women ◽  
Mode Of Delivery ◽  
Induction Of Labour ◽  
Cervical Ripening ◽  
Singleton Pregnancy ◽  
College Hospital ◽  
Nulliparous Women ◽  
Unfavourable Cervix ◽  
Oral Group ◽  
Vaginal Misoprostol

It is sometimes difficult to select the most effective, easy to use, safest, widely accepted and less expensive method for induction of labour and thereby spontaneous vaginal delivery. Prostaglandin E1 analogue ie misoprostol as a successful method both in oral and vaginal form has been used for induction of labour. The present study was conducted with an aim to compare the efficacy and safety of oral and vaginal administration of misoprostol tablets for cervical ripening and induction of labour in pregnant women using similar dosing regimen in two groups of pregnant women. A prospective randomized trial was done on one hundred pregnant women for the purpose. They were between 37 and 42 weeks of gestation with singleton pregnancy, cephalic presentation and unfavourable cervix (modified Bishops score of 4 or less) in the department of Obstetrics and Gynaecology of Dhaka Medical college Hospital during the period between February 2003 and March 2004. The mode of delivery did not vary significantly between the two groups. Mean induction delivery interval, mean doses of misoprostol, number of women delivered within 24 hours, oxytocin requirement and mean time to delivery were nearly similar in the two groups. Only nulliparous women in oral group took longer time to deliver than vaginal group though it was not statistically significant. The mode of delivery also did not differ significantly. The proportion of emergency caesarean section was high in vaginal group than oral group. Neonatal outcome was satisfactory and the results were comparable. (J Bangladesh Coll Phys Surg 2006; 24: 44-49)

scholarly journals Ultrasonic diagnosis of asymptomatic rupture of uterine in second trimester of pregnancy after laparoscopic surgery for interstitial pregnancy: a case report

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Chun Tong ◽  
Lijun Gong ◽  
Yuan Wei ◽  
Zhaohui Liu ◽  
Yiting Wang ◽  
...  
Keyword(s):  
Laparoscopic Surgery ◽  
Pregnant Women ◽  
Uterine Rupture ◽  
Wedge Resection ◽  
Previous History ◽  
Second Trimester ◽  
Interstitial Pregnancy ◽  
Asymptomatic Patients ◽  
History Of ◽  
Laparoscopic Salpingectomy

Abstract Background Uterine rupture is a rare, life-threatening event in obstetrics that may be fatal for the mother and fetus. Therefore, obstetricians need to pay attention to and should consider the antenatal diagnosis of uterine rupture in women having its risk factors. Successful conservative management for asymptomatic uterine rupture due to previous laparoscopic surgery for interstitial pregnancy has already been reported but remains understudied. Case presentation A 39-year-old woman was diagnosed asymptomatic uterine rupture at 22 weeks gestation by a routine second-trimester ultrasound scan. She had a history of laparoscopic salpingectomy with cornual wedge resection for interstitial pregnancy 10 months before this pregnancy. Refusing doctor’s twice advice of terminating the pregnancy, the patient insisted carrying on the pregnancy, and followed up by ultrasound and magnetic resonance imaging. Fetal growth was appropriate, fetal movements were good and the patient had no symptoms, without uterine contraction or amniotic fluid loss throughout follow-up period. Caesarean section was carried out at 34 + 1 weeks with a good maternal and neonatal outcome. Conclusions A previous history of laparoscopic salpingectomy with cornual wedge resection could be a risk factor for uterine rupture in pregnant women. Sonographers should be alert to this potential risk in pregnant women with a history of laparoscopic salpingectomy with cornual wedge resection even in asymptomatic patients.

scholarly journals Contextual influences on the perception of pregnant women who use drugs: Information about women’s childhood trauma history reduces punitive attitudes

2019 ◽  
Author(s):  
Brianna C Delker ◽  
Amanda Van Scoyoc ◽  
Laura K. Noll
Keyword(s):  
Pregnant Woman ◽  
Drug Use ◽  
Pregnant Women ◽  
Childhood Trauma ◽  
Contextual Information ◽  
Contextual Influences ◽  
Punitive Attitudes ◽  
History Of Childhood ◽  
Trauma History ◽  
History Of

Punitive attitudes and consequences (e.g., incarceration) for prenatal illicit drug use persist in the United States despite evidence that these policies are ineffective and even harmful to women and children. For instance, the threat of these consequences can deter women from seeking healthcare, prenatal care, and drug treatment. Punitive responses may persist due to pejorative public perceptions of pregnant women who use illicit drugs. Although there is evidence that contextual information about prenatal drug use (e.g., drug type) can change such perceptions, other contextual influences are unknown. This experimental study tested whether receiving contextual information about a pregnant woman who uses drugs (specifically, her childhood trauma history) reduces punitive and increases supportive attitudes toward the woman. In a vignette-based 2(pregnancy status: pregnant/not pregnant) x 2(history of childhood trauma: interpersonal/non-interpersonal) between-subjects design, young adult university participants (N=461) were randomly assigned to read a vignette about a woman who uses methamphetamine. Punitive attitudes were significantly reduced by information that the pregnant woman had a history of childhood trauma, especially interpersonal (versus non-interpersonal) trauma (ηp2=.115). Supportive attitudes were not impacted (ηp2=.005). Information about the pregnant woman’s trauma history predicted less agreement with incarcerating her, only indirectly, through less punitive attitudes (R2=.21). Reductions in punitive attitudes were on the order of 1.5-2 points on 5-point self-report scales and controlled for participant gender and political conservatism. Results have practical implications for interdisciplinary work aimed at unlocking greater support for policies that help pregnant women make safe, informed decisions with dignity and access to healthcare.

The Use of Prostaglandin E2for Cervical Ripening in Patients Requiring Induction of Labour

1997 ◽  
Vol 25 (3) ◽  
pp. 159-166 ◽  
Author(s):  
A Caruso ◽  
L De Santis ◽  
B Carducci ◽  
S Ferrazzani ◽  
S De Carolis ◽  
...  
Keyword(s):  
Caesarean Section ◽  
Clinical Benefit ◽  
Caesarean Section Rate ◽  
Fetal Distress ◽  
Induction Of Labour ◽  
Cervical Ripening ◽  
Prostaglandin E ◽  
Bishop Score ◽  
Difficult Labour ◽  
Initial Score

A total of 290 women who required induction of labour for medical or obstetric reasons were given single or multiple doses of prostaglandin E2 gel (0.5 mg) to induce cervical ripening. Onset of labour occurred in 185 (63.8%) of the women treated with the gel, without any further treatment. The overall Caesarean section rate was 27.2% (79/290) and was significantly higher among those with an initially low Bishop score than in those with a higher initial score (34.7% versus 22.1%; P = 0.025). Prostaglandin E2 gel appears to be of considerable clinical benefit, especially where no other options are available except Caesarean section or a very long, difficult labour that may result in significant fetal distress.

scholarly journals Efficacy of Dinoprostone Vaginal Pessary for Cervical Ripening and Induction of Labour

2021 ◽  
Vol 10 (12) ◽  
pp. 873-877
Author(s):  
Mamatha C ◽  
Sarmishta M ◽  
Dhanalakshmi M.G
Keyword(s):  
Pregnant Women ◽  
Vaginal Delivery ◽  
Active Phase ◽  
Induction Of Labour ◽  
Cervical Ripening ◽  
Labour Induction ◽  
Time Interval ◽  
Delivery Time ◽  
Phase Time ◽  
Vaginal Pessary

BACKGROUND To evaluate the efficacy of dinoprostone vaginal pessary for cervical ripening and labour induction in term pregnant women. METHODS This was a prospective observational study conducted at Sri Ramachandra Institute of Higher Education and Research from September 2016 to September 2018. The study included pregnant women with singleton pregnancy and gestational age (GA) between 37 weeks and 41 weeks of gestation. The estimated sample size was 100. All 100 women were induced with dinoprostone vaginal pessary. RESULTS The average induction to active phase interval was 10 hours 58 minutes. About 60.3 % of primigravida had an active phase time interval of 12 hours 03 minutes; and 95.2 % of primigravida delivered < 24 hours with a mean induction to delivery time interval of 17 hours 36 minutes. 4 % of primigravida had failed induction. About 84.8 % of multigravida delivered with mean induction to active phase time interval of 08 hours 57 minutes and 100 % of multigravida delivered < 24 hours with a mean induction to delivery time interval of 12 hours 19 minutes. Out of 100 patients, 80 % of patients delivered by spontaneous vaginal delivery with episiotomy, 5 % of patients delivered by assisted vaginal delivery with episiotomy and 15 % of patients delivered by Caesarean section. Almost 97 % of multiparous women delivered vaginally. No adverse maternal and neonatal outcome was noted in the present study. CONCLUSIONS Dinoprostone vaginal pessary is highly effective in the induction of labour at term in properly selected cases. In terms of success and failure, dinoprostone vaginal pessary does not differ much from dinoprostone gel. KEY WORDS Labour Induction, Propess, Dinoprostone

scholarly journals Severe COVID-19 in Third Trimester Pregnancy: Multidisciplinary Approach

2020 ◽  
Vol 2020 ◽  
pp. 1-8 ◽  
Author(s):  
Jerald Pelayo ◽  
Gabriella Pugliese ◽  
Grace Salacup ◽  
Eduardo Quintero ◽  
Adeeb Khalifeh ◽  
...  
Keyword(s):  
Pregnant Woman ◽  
Pregnant Women ◽  
Respiratory Acidosis ◽  
Inpatient Rehabilitation ◽  
Morbidly Obese ◽  
Third Trimester ◽  
Health Crisis ◽  
History Of ◽  
Maternal And Neonatal Outcomes ◽  
Oxygen Requirements

The rapidly expanding cases of the coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have exposed vulnerable populations, including pregnant women to an unprecedented public health crisis. Recent data show that pregnancy in COVID-19 patients is associated with increased hospitalization, admission of the intensive care unit, and intubation. However, very few resources exist to guide the multidisciplinary team in managing critically ill pregnant women with COVID-19. We report our experience with managing a morbidly obese pregnant woman at 36 weeks’ gestation with history of asthma and malignancy who presented with persistent respiratory symptoms at an outside hospital after being tested positive for SARS-CoV-2 polymerase chain reaction (PCR). Early in the course of the hospitalization, patient received remdesivir, convalescent plasma, bronchodilator, systemic steroids, and IV heparin for COVID-19 and concomitant asthma exacerbation and pulmonary embolism. Due to increasing oxygen requirements, she was eventually intubated and transferred to our institution for higher level of care. Respiratory acidosis, severe hypoxemia, and vent asynchrony were managed with vent setting adjustment and paralytics. After 12 hours from spontaneous rupture of her membranes and with stabilization of maternal status, patient underwent a term cesarean delivery for nonreassuring fetal heart tracing. The neonate was discharged on the 2nd day of life, while the patient was extubated on the 6th postpartum day and was discharged to acute inpatient rehabilitation facility on the 19th hospital day. This report highlights the disease progression of COVID-19 in a pregnant woman, the clinical challenges in the critical care aspect of patient management, and the proposed multidisciplinary strategies utilizing an algorithmic approach to optimize maternal and neonatal outcomes.

Effect of Dehydroepiandrosterone Sulphate, Oestrogens and Prostaglandins on Collagen Metabolism in Human Cervical Tissue in Relation to Cervical Ripening

1993 ◽  
Vol 21 (1) ◽  
pp. 26-35 ◽  
Author(s):  
K Yoshida ◽  
R Tahara ◽  
T Nakayama ◽  
T Yanaihara
Keyword(s):  
Enzyme Activity ◽  
Pregnant Women ◽  
Incubation Medium ◽  
Cervical Ripening ◽  
Prostaglandin E ◽  
Cervical Tissue ◽  
Dehydroepiandrosterone Sulphate ◽  
Collagenase Activity ◽  
Oestrone Sulphate ◽  
Prostaglandin F

To clarify the mechanism of cervical ripening at term, collagenase activity in human cervical tissue was studied. The effects of steroids and prostaglandins on collagenase activity were also examined. Collagenase activities in cervical tissues obtained from non-pregnant ( n = 5) and pregnant women (early-pregnant, n = 3; late-pregnant, n = 14) were measured, with or without the addition of steroids and prostaglandins into the incubation medium prior to the measurement of enzyme activity. The enzyme activity was significantly (P < 0.01 − 0.05) higher in the cervical tissue obtained from late-pregnant women than that from non-pregnant and early-pregnant women. Collagenase activity was significantly ( P < 0.05) elevated when steroid sulphates such as dehydroepiandrosterone sulphate and oestrone sulphate were added to the incubation medium, while the addition of free steroids, prostaglandin E2 and prostaglandin F2α did not alter the activity. These data suggest that conjugated steroid produced in the foetoplacental unit during pregnancy may be involved in cervical ripening through the enhancement of collagenase activity.

scholarly journals A randomized prospective comparative study to evaluate the efficacy of prostaglandin E2 (Dinoprostone) controlled release vaginal insert versus sublingual prostaglandin E1(Misoprostol) in induction of labor in term gestation

2021 ◽  
Vol 8 (4) ◽  
pp. 457-462
Author(s):  
Rakhee Sahu ◽  
Kirti Janjewal
Keyword(s):  
Comparative Study ◽  
Pregnant Women ◽  
Fetal Outcome ◽  
Induction Of Labor ◽  
Induction Of Labour ◽  
Cervical Ripening ◽  
Significant Difference ◽  
Misoprostol Group ◽  
Prospective Comparative Study ◽  
The Mean

In modern obstetrics, one of the common challenges is induction of labour (IOL). WHO Global Survey reported that IOL accounted for 9.6% of all deliveries. Prostaglandins have evolved and frequently used pharmacologic agents for IOL, owing to their dual action of cervical ripening and uterine contraction inducing effect. : 1. To compare the efficacy and induction to delivery interval (IDI) of PGE2 vaginal insert and Sublingual PGE1 in induction of labor in term pregnant women; 2. To study the maternal and fetal outcome in both groups.: This a randomized, prospective, comparative study of 100 term pregnant women for induction of labour. Group 1-(50 women) PGE2-10mg vaginal insert and group 2-(50 women) PE1 Sublingual tablets – maximum 200 mcg in 24 hrs, at Dr LH Hiranandani Hospital, Mumbai, India.: In my study the mean induction to delivery interval in Dinoprostone group was 17.47 hours and 23.44 hours in Misoprostol group. So the mean IDI was shorter in Dinoprostone insert group than Misoprostol group by about 6 hours. There was no significant difference noted in terms of overall incidence of caesarean deliveries among the groups. Our study concluded that Dinoprostone 10mg vaginal insert was more efficacious than sublingual Misoprostol in reducing induction to delivery interval without maternal and fetal complications.Our study suggests that the Dinoprostone vaginal insert can be used as both inducing as well as augmentating agent in labour. Dinoprostone vaginal insert maybe more effective in reducing the incidence of caesarean sections.

Kết quả điều trị phẫu thuật nội soi viêm ruột thừa ở phụ nữ mang thai tại Bệnh viện Đa khoa Tỉnh Thái Bình

2021 ◽  
Author(s):  
Tuan Dat Pham
Keyword(s):  
Laparoscopic Surgery ◽  
Pregnant Woman ◽  
Preterm Birth ◽  
Surgical Treatment ◽  
Pregnant Women ◽  
General Hospital ◽  
Results Of Treatment ◽  
Hospital Transfer ◽  
Key Words Acute Appendicitis ◽  
Low Rate

TÓM TẮT Mục tiêu: Đánh giá kết quả điều trị phẫu thuật nội soi viêm ruột thừa ở phụ nữ mang thai tại bệnh viện Đa khoa tỉnh Thái Bình. Phương pháp nghiên cứu: Mô tả hồi cứu 35 trường hợp viêm ruột thừa ở phụ nữ mang thai được điều trị phẫu thuật nội soi. Kết quả: 100% bệnh nhân được mổ cắt ruột thừa nội soi. Thời gian phẫu thuật trung bình 50,7 ± 13,6 phút (30 - 70 phút). Thời gian phẫu thuật kéo dài hơn ở nhóm viêm phúc mạc ruột thừa (56,7 ± 8 (40 - 70) phút) so với viêm ruột thừa mà không có viêm phúc mạc (p < 0,05). Có 3 trường hợp phải chuyển viện do sốt, dọa sẩy thai, dọa đẻ non. Kết quả điều trị 91,4 % kết quả tốt; 8,6% kết quả trung bình, không có trường hợp nào thai phụ bị tử vong, không có thai nhi bị tử vong. Kết luận: Phẫu thuật nội soi ổ bụng có thể ứng dụng an toàn để điều trị viêm ruột thừa ở phụ nữ mang thai, với tỉ lệ tai biến và biến chứng thấp cho thai phụ và thai nhi. ABSTRACT THE RESULTS OF TREATING APPENDICITIS USING LAPAROSCOPIC SURGERY IN PREGNANT WOMEN IN THAI BINH PROVINCIAL GENERAL HOSPITAL Objective: To evaluate the results of appendicitis endoscopic surgical treatment in pregnant women at Thai Binh Provincial General Hospital. Method: Retrospective describe of 35 pregnant women diagnosed with appendicitis treated using laparoscopic surgery. Results: 100% of patients underwent laparoscopic appendectomy. Average surgery time 50,7 ± 13,6 minutes (30 - 70 minutes). Surgery time was longer in the group of appendicitis (56,7 ± 8 (40 - 70) minutes) compared with appendicitis without peritonitis (p < 0,05). There were 3 cases of hospital transfer due to fever, threat of miscarriage, threat of preterm birth. Results of treatment 91,4% of the results were good; 8,6% of the average results, no case of death of the pregnant woman, no death of the fetus. Conclusion: Abdomen endoscopic surgical treatment can be used to treat appendicitis in pregnant women with low rate of complications for both the women and fetus. Key words: Acute appendicitis, appendicitis in pregnant women

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