scholarly journals Jugular Vein Insufficiency and Choroidal Neovascularization in Moderate Myopia: A New Unknown Factor of Additional Risk?

2015 ◽  
Vol 2015 ◽  
pp. 1-4
Author(s):  
Massimiliano Farina ◽  
Cristiano Ratti ◽  
Eugenio Novelli
Keyword(s):  
Choroidal Neovascularization ◽  
Potential Role ◽  
Color Doppler ◽  
Venous Drainage ◽  
Choroidal Blood Flow ◽  
Additional Risk ◽  
Doppler Study ◽  
Blood Flow Reduction ◽  
Local Reduction

To date, choroidal blood flow reduction in highly myopic eyes appears to be related to the development of choroidal neovascularization secondary to local reduction of arterial flow. Instead, no evidence of choroidal neovascularization was found in subjects with low or moderate myopia. The authors’ aim has been to encourage new studies regarding the potential role of chronic retinal venous congestion in the pathogenesis of choroidal neovascularization. In December 2011, a 54-year-old woman with moderate bilateral myopia had a sudden block upon swallowing while she was eating. Subsequently (January 2013) metamorphopsia in the left eye revealed macular degeneration with choroidal neovascularization. The related echo-color Doppler study of the neck veins, performed in November 2014, showed an atypical left jugular insufficiency associated with homolateral hypertension of the superior ophthalmic veins. This singular case highlights the necessity to further investigate the potential role of chronic alterations of intra- and extracranial venous drainage in the disruption of choroidal flow in myopic patients.

EVALUATION OF EPIDIDYMORCHITIS BY HIGH FREQUENCY GRAY SCALE AND COLOR DOPPLER ULTRASONOGRAPHY

2021 ◽  
pp. 54-56
Author(s):  
Akhil Sharma ◽  
Sameer R. Verma ◽  
Neeraj Prajapati ◽  
Vinod Kumar Mogha
Keyword(s):  
High Frequency ◽  
Doppler Ultrasonography ◽  
Low Cost ◽  
Color Doppler ◽  
Color Doppler Ultrasonography ◽  
The Body ◽  
Mri Imaging ◽  
Gray Scale ◽  
Doppler Study

INTRODUCTION: Ultrasonography is extremely well suited to study of scrotum and its contents. Ultrasound is simple to perform, quick, non-invasive, low cost effective, easily reproducible, widely available and does not involve irradiation of gonads.It is very helpful in differentiating intratesticular and extratesticular pathologies. Ultrasound is the modality to differentiate solid from cystic lesions of testes and with the introduction of color Doppler, it becomes easiear to assess the viability of testis in cases of torsion and guiding the treatment accordingly. USG is helpful in differentiating torsion/ischaemia of testis from the acute inammatory pathologies. Role of other Modalities: CT and MRI have dominated imaging of other regions of the body, they have certain restrictions in evaluation of scrotal diseases. Computed Tomography delivers radiation to gonads, On the contrary, MRI imaging is expensive and not readily obtainable. Radionuclide scan helps in equivocal presentations to assess vascularity within the testis in setting of torsion but its readily availability and cost is the main set back. AIM: To assess the role of high frequency gray scale and color doppler ultrasonography in evaluation of epididymorchitis. MATERIAL & METHODS: SAMPLE: 50 cases of scrotal pathology were taken using High-frequency real time gray scale ultrasonography and Color Doppler . Patients were referred to our department for scrotal ultrasonography and Doppler study by department of Urology and department of Surgery of SRMS IMS Bareilly. RESULTS: In the present study total evaluated cases of epididymoorchitis were 15,among them 11 cases were acute and 4 cases were of chronic epididymoorchitis.. Majority of cases were having unilateral involvement with 1 case of B/L involvement. USG gray scale found heterogenous echogenicity or reduced echogenicity in acute EPO while the echogenicity was reduced with calcication in chronic EPO. .Doppler study found increased vascularity in majority of cases of acute EPO with reactive hydrocele while vascularity was either normal or increased in chronic EPO without any reactive hydrocele. CONCLUSION: High-frequency gray scale USG helps in clear evaluation of anatomical structural alterations associated with acute scrotal inammatory diseases, and color Doppler USG is highly sensitive in diagnosing acute scrotal pathology. In addition, Color Doppler USG accurately differentiates between testicular ischemia and torsion from acute inammatory diseases in acute painful scrotal conditions.

scholarly journals Role of ultrasound and color Doppler in the evaluation of acute scrotal pain

2018 ◽  
Vol 50 (1-2) ◽  
pp. 26-30
Author(s):  
Gazi Salahuddin ◽  
SM Zulker Nayeem ◽  
Syed Mozammel Hossain ◽  
Sadika Parvin ◽  
Md Monoar Hossain
Keyword(s):  
Morphological Changes ◽  
Color Doppler ◽  
Definitive Diagnosis ◽  
Relative Importance ◽  
Colour Doppler ◽  
Gray Scale ◽  
Scrotal Pain ◽  
Doppler Study ◽  
Acute Scrotal Pain

Background: Traditionally acute scrotal pain is evaluated by gray scale ultrasound, which dissipated only the morphological changes of the lesion. But pattern of vascularity either normal, increased or absent of affected structure help to definitive diagnosis of the lesion and help to proceed the type of management either medical therapy or surgical treatment.Objectives: To determine the relative importance of color Doppler in the evaluation of acute scrotal pain by ultrasound.Methods: From June 2013 to June 2017 a total 150 patients with acute scrotal pain were selected. A thorough history taking and physical examination were done. Then patient were scanned with gray scale ultrasound followed by color Doppler study. Color Doppler diagnosis is compared with gray scale diagnosis.Results: In gray scale ultrasonography among the 150 cases, 54% were diagnosed as epididymitis, 16.66% were epididymo-orchitis and 16% patient diagnosed as normal. But in combined gray scale and colour Doppler study 58% were diagnosed as epididymitis, 22% were epididymo-orchitis and 6% of patient diagnosed as normal. In gray scale 10% patient were diagnosed as normal but become epididymitis and epididymo-orchitis in colour Doppler. Four percent were diagnosed as epididymitis in gay scale but became epididymo-orchitis in colour Doppler. Four percent patient was diagnosed as epididymitis orchitis but became testicular torsion in Doppler study. Total 14.66% of gray scale diagnosis became another diagnosis in the Doppler study.Conclusion: Combined gray scale and color Doppler study is superior than gray scale ultrasound in differentiating various cause of acute scrotal pain.Bang Med J (Khulna) 2017; 50 : 26-30

Skin vascular bed is a potential blood reservoir during heat stress

1990 ◽  
Vol 259 (6) ◽  
pp. H1796-H1802 ◽  
Author(s):  
A. Deschamps ◽  
S. Magder
Keyword(s):  
Heat Stress ◽  
Potential Role ◽  
Static Pressure ◽  
Venous Drainage ◽  
Force Transducer ◽  
Skin Flaps ◽  
Venous Compliance ◽  
Occlusion Technique ◽  
Blood Reservoir

To determine the potential role of the skin vasculature as a blood reservoir, we measured venous compliance (Cv), resistance (Rv), and their product, the time constant of venous drainage (tau sk = RvCv), in skin flaps from the hindlimbs of 15 dogs anesthetized with pentobarbital sodium at different core temperatures (Tc, 37-42 degrees C), skin temperature (Ts, 25.3-50.0 degrees C), and during an infusion of papaverine (5%). The vasculature of the flap was isolated, and a double-occlusion technique was used to measure the static pressure in the venous compartment. The blood volume of the flap was altered by changing either flow or outflow pressure (Pv). The change in volume was estimated from the change in weight of the flap with a force transducer. At Tc = 37 degrees C, Rv was 2.27 +/- 0.81 mmHg.min.ml-1.100 g-1 (means +/- SD), Cv was 0.17 +/- 0.06 ml.mmHg-1.100 g-1, and tau sk was 28.0 +/- 8.8 s. Rv decreased with elevated Tc, Ts, and with papaverine. Cv increased with a rise in Tc and Ts. Increasing Tc and Ts did not change tau sk, but the papaverine infusion shortened it. The lowest tau sk (20 s) occurred during maximal vasodilatation. This long tau sk indicates that the skin could serve as a blood reservoir during heat stress.

scholarly journals The predictive role of color doppler sonography in evaluating hypoxia and acidosis in intrauterine growth restriction fetuses: correlation with arterial blood gas analysis

2020 ◽  
Vol 9 (3) ◽  
pp. 1119
Author(s):  
Triptpal Kaur ◽  
Reema Kumar Bhatt
Keyword(s):  
Doppler Sonography ◽  
Color Doppler ◽  
Gas Analysis ◽  
High Pco2 ◽  
Ultrasound Technique ◽  
Arterial Blood Gas ◽  
Arterial Blood ◽  
Doppler Study ◽  
Number Of Patients

Background: Doppler is an ultrasound technique allowing non-invasive measurement of artery blood flow velocities. Objective of this study was to evaluate the role of umbilical artery (UA) and middle cerebral artery (MCA) Doppler study in predicting fetal hypoxia and acidosis in IUGR fetus and a population subjected to hematologic fluctuations.Methods: In this study 100 subjects with IUGR fetuses was evaluated for comparison of Doppler sonography analysis of fetal middle cerebral arteries and umbilical arteries and cord blood samples (pCO2, pO2) that was collected at the time of delivery.Results: Among the 100 subjects (between 28-32 gestational week) of IUGR showed a high risk of hypoxia and acidosis type condition. The observations were recorded in terms of MCA/UA ratio, the abnormal MCA/UA ratio was observed in significant (p<0.05) number of patients growth restricted fetuses (n=96), as compared to normal. There is a direct correlation found in the pH and pCO2 values. The results of arterial blood gases with respect to pH were found to be less than 7.3±1.6 in 96 subjects with abnormal MCA/UA ratio as compared to normal, that relates to the increase in the relative pCO2 (61.66%) [Acid increase] and decrease in pO2 arterial gases (Hpoxia increase).Conclusions: The study provides an insight that shows IUGR fetuses have a relatively higher risk of hypoxia (less oxygen) and acidosis (low pH and high pCO2), showed the most important determinants variations.

scholarly journals The Role of Doppler Ultrasound in the Diagnosis of Postnatal Testicular Torsion in Children

2021 ◽  
pp. 69-81
Author(s):  
E. B. Olkhova ◽  
S. Yu. Borisov ◽  
M. V. Topolnik ◽  
A. Yu. Tagirova ◽  
S. V. Zhumasitov ◽  
...  
Keyword(s):  
Blood Flow ◽  
Prognostic Value ◽  
Testicular Torsion ◽  
Neonatal Period ◽  
Color Doppler ◽  
Diagnostic Significance ◽  
Doppler Study ◽  
Testicular Blood Flow

The diagnostic significance of the color Doppler study of testicular blood flow in testicular torsion has been studied for about 40 years, however, the prognostic value of the results obtained is ambiguous, as are the actual imaging capabilities of the technique. Our own experience of 110 observations of testicular torsion in children older than the neonatal period allows us to draw statistically reliable conclusions. Made on equipment premium-class research made it possible to evaluate how visualization intratesticular vascular pattern, and whirpool-sign and submit the primitive model of the actual inversion, explaining the impossibility of rendering whirpool-sign with the greatest tight inversion. The dynamics of testicular blood flow was studied immediately after successful and unsuccessful manual detorsion and in the long term after operative detorsion and orchopexy. The publication contains a brief analysis of the literature and is extensively illustrated.

scholarly journals Potential role of sirtuin 1 in Müller glial cells in mice choroidal neovascularization

PLoS ONE ◽  
2017 ◽  
Vol 12 (9) ◽  
pp. e0183775 ◽  
Author(s):  
Tomoka Ishida ◽  
Takeshi Yoshida ◽  
Kosei Shinohara ◽  
Kejia Cao ◽  
Ken-ichi Nakahama ◽  
...  
Keyword(s):  
Choroidal Neovascularization ◽  
Glial Cells ◽  
Potential Role ◽  
Sirtuin 1 ◽  
Müller Glial Cells

IMO 1605 Port L hypertensive gastropathy: Potential role of Levovist® enhanced color doppler

1997 ◽  
Vol 23 ◽  
pp. S31
Author(s):  
M.J. Gebel ◽  
M. Caselitz ◽  
K. Sterath ◽  
C. Schoefl ◽  
P.N. Meier ◽  
...  
Keyword(s):  
Potential Role ◽  
Color Doppler

POPDC proteins and cardiac function

2019 ◽  
Vol 47 (5) ◽  
pp. 1393-1404 ◽  
Author(s):  
Thomas Brand
Keyword(s):  
Potential Role ◽  
Striated Muscle ◽  
Short Review ◽  
Effector Proteins ◽  
Muscle Disease ◽  
Disease Genes ◽  
Protein Protein Interaction ◽  
Interaction Partners ◽  
And Function

Abstract The Popeye domain-containing gene family encodes a novel class of cAMP effector proteins in striated muscle tissue. In this short review, we first introduce the protein family and discuss their structure and function with an emphasis on their role in cyclic AMP signalling. Another focus of this review is the recently discovered role of POPDC genes as striated muscle disease genes, which have been associated with cardiac arrhythmia and muscular dystrophy. The pathological phenotypes observed in patients will be compared with phenotypes present in null and knockin mutations in zebrafish and mouse. A number of protein–protein interaction partners have been discovered and the potential role of POPDC proteins to control the subcellular localization and function of these interacting proteins will be discussed. Finally, we outline several areas, where research is urgently needed.

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