scholarly journals Rare Intracardiac Tumor: Primary Cardiac Lymphoma Presenting as Atypical Angina

2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
Karthigesu Aimanan ◽  
K. Saravana Kumar ◽  
M. N. Mohd Arif ◽  
Md Noor Zuraini ◽  
Md Jamil Ramdzan ◽  
...  
Keyword(s):  
Treatment Plan ◽  
Cardiac Risk ◽  
Rapid Onset ◽  
Cardiac Tumors ◽  
Rare Presentation ◽  
Cardiac Lymphoma ◽  
Primary Cardiac Lymphoma ◽  
Emergency Resection ◽  
Primary Cardiac Tumors

Primary lymphomas of the heart are extremely rare, accounting for 2% of all primary cardiac tumors. Due to the rare presentation, there is no proper consensus available on treatment strategy. Preoperative confirmation of the pathology is fundamental in guiding an early treatment plan, which allows for improved prognosis. Unfortunately, in most cases, primary cardiac lymphoma is only identified on postoperative histopathological analyses, which affect the treatment plan and outcome. Here, we report a unique case of primary cardiac lymphoma presented with dyspnea and reduced effort tolerance. Young age, rapid onset of symptom, and absence of cardiac risk factors prompted us towards further imaging and emergency resection. The patient received a course of postoperative chemotherapy and was disease-free on six months of follow-up.

scholarly journals Two Decades of Contemporary Surgery of Primary Cardiac Tumors

2018 ◽  
Vol 04 (04) ◽  
pp. e176-e181
Author(s):  
Khalil Jawad ◽  
Tamer Owais ◽  
Stefan Feder ◽  
Sven Lehmann ◽  
Martin Misfeld ◽  
...  
Keyword(s):  
Artery Bypass ◽  
Golden Rule ◽  
Tumor Location ◽  
Cardiac Tumors ◽  
Complete Excision ◽  
Presenting Symptoms ◽  
Single Center Experience ◽  
Cardiac Procedures ◽  
Primary Cardiac Tumors

Objective The decision to operate cardiac tumors is an issue of balancing surgical outcome and survival with quality of life (QOL). We report our single-center experience in managing primary cardiac tumors between 1994 and 2014. Methods and Results In this study, 269 patients were subjected to our standardized operative protocols, preoperative preparations, postoperative follow-up, and consents of participation. Demographic and preoperative/intraoperative/postoperative variables were collected with focus on long-term follow-up and survival. A total of 72,000 cardiac procedures were performed within 20 years at our institution. Two hundred sixty-nine patients were diagnosed with primary cardiac tumors (0.37%), with a male:female ratio of 1:1.68, mean age of 57.4 ± 19.5 years, and body mass index of 25.49 ± 6.5. The most presenting symptoms were dyspnea (n = 94), arrhythmias (n = 53), embolic event (n = 36), and chest pain (n = 29), and 33 patients were accidentally discovered. Isolated tumor excision and concomitant ablation were performed on 181 patients, while the rest needed additional procedures such as coronary artery bypass grafting (n = 27) or valve surgery (n = 61). Focus on pathology, tumor location was done reporting the commonest pathology such as myxoma (n = 177) and fibroelastoma (n = 56). The frequent site was the left atrium (n = 162). Our primary results showed incidence of bleeding in 9 patients (3.3%), arrhythmias in 76 patients (28.25%), and mortality in 49 patients (18.2%). Five patients (1.8%) showed recurrence and 220 patients (81.8%) showed complaint-free survival. Conclusion Complete excision of primary cardiac tumors is the golden rule in management as it improves survival and decreases morbidity expected from the progressing tumors process. The progression of minimally invasive techniques improves QOL and should be performed whenever possible.

scholarly journals Left-sided primary cardiac lymphoma: a case report

2020 ◽  
Vol 32 (1) ◽  
Author(s):  
Valentina Scheggi ◽  
Carlotta Mazzoni ◽  
Tiziano Mariani ◽  
Pier Luigi Stefàno
Keyword(s):  
Poor Prognosis ◽  
Pulmonary Veins ◽  
B Cell Lymphoma ◽  
Rapid Progression ◽  
Cardiac Tumors ◽  
Right Heart ◽  
Ct Guided ◽  
Cardiac Lymphoma ◽  
Primary Cardiac Lymphoma ◽  
Heart Rupture

Abstract Background Primary cardiac lymphoma (PCL) is a rare neoplasm, defined as lymphoma with the main bulk localized in the heart; diffuse large B cell lymphoma (DLBCL) is the most common type. It usually involves the pericardium and the right heart and has a poor prognosis with a median survival of less than 1 year. Case presentation A 62-year-old female presented to the emergency department for palpitations and recent-onset dyspnea. The echocardiogram showed a round-shaped mass (33 x 32 mm) in the left atrium, a mild circumferential pericardial effusion, and a hyperechogenic mass at the level of the atrio-ventricular junction. A thoracic CT scan demonstrated the presence of a bulky mediastinal mass, strictly attached to the left heart and infiltrating its posterior wall, the left pulmonary veins, and the inferior lobar bronchus. The patient underwent CT-guided biopsy, and the diagnosis of double-expressor DLBCL was made. Given the potential risk of heart rupture during chemotherapy, the first cycle of R-CHOP was performed in an in-hospital setting, with initial benefit. After completing 6 cycles of R-CHOP, imaging studies showed rapid progression of the disease; the patient was started on the salvation protocol R-DHAOX but died of septic shock 10 months later. Conclusions PCL is rare and accounts for less than 2% of primary cardiac tumors; double-expressor DLBCL carries a poor prognosis. As in most cases, the diagnosis was made after the onset of nonspecific symptoms (dyspnea) but—despite the strong predilection for right heart involvement reported in literature—our patient had a predominant left atrial infiltration.

scholarly journals Cardiac Papillary Fibroelastoma with Coronary Artery Anomaly: A Case Report

2017 ◽  
Vol 20 (2) ◽  
pp. 052
Author(s):  
Hongfei Xu ◽  
Liangwei Chen ◽  
Chengmeng Ye ◽  
Kwabena Gyabaah Owusu-Ansah ◽  
Yiming Ni ◽  
...  
Keyword(s):  
Tumor Recurrence ◽  
Papillary Fibroelastoma ◽  
Cardiac Tumors ◽  
High Resolution Imaging ◽  
Aortic Cusp ◽  
Cardiac Neoplasms ◽  
Resected Tumor ◽  
Resolution Imaging ◽  
Primary Cardiac Tumors

Primary cardiac tumors are extremely rare with occurrence range of about 0.0017-0.28%. Papillary fibroelastoma is a benign cardiac neoplasms. Improvement in the early diagnosis has been made possible with the help of high-resolution imaging technology, such as transesophageal echocardiography, combined with ischemic or embolic complications which patients typically present with clinically. We herein present a 51-year-old female patient with a papillary fibroelastoma on the aortic cusp, with its origin from the left coronary sinus. Her only clinical manifestation was angina-like chest pain and syncope. Surgical resection with aortic valve replacement due to the defect as a result of the resected tumor was performed with the patient on cardiopulmonary bypass. The patient recovered uneventfully and was discharged.  A 2-year follow-up showed an intact valve without tumor recurrence.

scholarly journals A case report of left atrial myxoma presenting with amnesia

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Sadegh Shabab ◽  
Majid Erfanzadeh ◽  
Shamsa Ahmadian ◽  
Maryam Mahmoudabady ◽  
Naser Mazloum
Keyword(s):  
Left Atrial ◽  
Cardiac Myxoma ◽  
Common Type ◽  
Atrial Myxoma ◽  
Cardiac Tumors ◽  
Surgery Complications ◽  
Case Presentation ◽  
Left Atrial Myxoma ◽  
Primary Cardiac Tumors

Abstract Background Primary cardiac tumors are rare, and approximately 90% of them are benign. Myxoma is the most common type of these tumors occurring in the left atrium in 75–85% of cases. The tumor can cause the left atrio-ventricular valve obstruction and embolization phenomenon. Case presentation We reported a case of 54-year-old man with complaints of dyspenea and amnesia. In our patient, transthoracic echocardiography revealed a mass of 28*63 mm attached to the upper intra-atrial septum, which was prolapsing through the mitral valve into the left ventricle during diastole, being indicative of the left atrial myxoma. On examination, he was alert and conversant, and no pathological abnormality was observed in the examination of cardiovascular, gastrointestinal, respiratory, hepatic, renal and nervous systems. After myxoma diagnosis, the tumor was removed under cardiac surgery and discharged under good conditions. In the telephone follow-up after discharge, the patient recovered and did not report the disease and surgery complications. Conclusions Patients with cardiac myxoma are usually asymptomatic, but they may have manifestations related to the embolism phenomenon or intracardiac obstruction. Therefore, myxoma may represent an emergency. Surgery should be performed as soon as possible. If surgery is delayed, the patient may suffer from serious and irreversible complications, such as stroke and cardiac arrest.

scholarly journals P650 A rare form of cardiac mass: primary cardiac lymphoma

2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
B Yagmur ◽  
E Simsek ◽  
B Ozbay ◽  
T Calkavur ◽  
M Kayikcioglu ◽  
...  
Keyword(s):  
B Cell Lymphoma ◽  
Cardiac Mass ◽  
Mass Lesion ◽  
Cardiac Tumors ◽  
Rare Form ◽  
Primary Tumors ◽  
Cardiac Lymphoma ◽  
Primary Cardiac Lymphoma ◽  
Vena Cava Superior ◽  
The Right

Abstract Funding Acknowledgements We declare no conflict of interest and no financial support A rare form of cardiac mass primary cardiac lymphoma Introduction Primary tumors of the heart are rare and constitute 5% of all cardiac masses. Primary cardiac lymphoma is a curable form of cancer that responds well to early diagnosis and chemotherapy. Case report 56 year old male patient presented to our outpatient clinic with abdominal swelling. Echocardiography revealed a mass lesion that surrounded the right ventricle and restricted ventricular diastolic function. The mass lesion was poorly discernable from normal myocardial tissue. Magnetic resonance imaging (MRI) showed an infiltrative mass lesion that filled the right pericardial space, and that surrounded the junction between vena cava superior and the right atrium, as well as the root of the aorta. Subxyphoidal biopsy revealed diffuse large B cell lymphoma. Patient died on the 10th day of chemotherapy. Discussion Primary cardiac lymphoma constitutes only 2% of all primary cardiac tumors. Cardiac lymphomas are curable in early stages with chemotherapy without the need for surgical excision. Cardiac lymphoma should be kept in mind when faced with a cardiac mass lesion and imaging modalities such as MRI and PET scanning and tissue biopsy should be utilized before planning surgical interventions since these lesions respond well to chemotherapy Abstract P650 Figure.

scholarly journals Surgical resection of a giant cardiac hemangioma encroached upon the right coronary artery: A case report

2020 ◽  
Author(s):  
guangpu fan ◽  
Yu Chen
Keyword(s):  
Case Report ◽  
Coronary Artery ◽  
Surgical Resection ◽  
Surgical Removal ◽  
Cardiac Tumors ◽  
Cardiac Hemangioma ◽  
Risk Of Rupture ◽  
The Right ◽  
Primary Cardiac Tumors

Cardiac hemangioma is relatively rare for primary cardiac tumors. The diagnose is mainly based on surgical resection and biopsy, imaging examinations only provide limited diagnostic clues. For those giant cardiac hemangiomas, which may raise a risk of rupture, need thoroughly surgical removal. However, meticulous follow-up is required due to its possibility of recurrence.

scholarly journals P185 Primary cardiac lymphoma: an unexpected finding

2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
A Riesgo ◽  
J Ibero ◽  
M Rodriguez ◽  
F De La Torre ◽  
J Muniz ◽  
...  
Keyword(s):  
Heart Failure ◽  
B Cell ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Cardiac Tumors ◽  
Unexpected Finding ◽  
Cardiac Lymphoma ◽  
Primary Cardiac Lymphoma ◽  
The Right ◽  
Right Atria

Abstract BACKGROUND Primary cardiac malignancies are rare, with a reported incidence of 0.1%. Up to 10% of cardiac tumors are malignant and primary cardiac lymphoma represents (PCL) a very low proportion of them. The wide variety of clinical manifestations and the inespecificity of them, difficults the diagnosis and delays treatment impacting directly in the prognosis of these patients. Here we present a lady with diagnosis of PCL treated in our center. CASE REPORT We present a 69 year old female with arterial hypertension and paroxismal atrial fibrilation that attended our clinic in april 2013. She referred severe dyspnoea with daily activities and peripheral oedema for the last three weeks. She also complaint of painful swallowing for bothliquids and solids. Physical exploration was unremarkable and observations where within normal limits. Transthoracic echocardiogram (TTE) was performed which showed an hipoechogenic mass invading the right ventricle, both atria and left ventricle outflow tract. She underwent cardiac MRI which revealed a myocardial isointense mass, with marked signal enhancement in T2 and heterogeneity in late gadolinium enhancement sequences, that was consistent with primary cardiac lymphoma. For histologycal characterization, biopsy of the mass guided with endoscopic ultrasonography was performed, confirming B-cell lymphoma. Positron emmision tomography (PET) scan showed bulky hypercaptant mass invading both atria, superior vena cava and pericardium, with hypercaptant adenopathies in right pulmonary hilum, subcarinal and phrenic chain. Her case was discussed in multidisciplinary team meeting and prompt initiation of treatment under R-CHOP regime was decided. After three cycles, follow up PET was requested, and revealed complete metabolic response. A repeat TTE showed only minimal infiltration of the right atria without ventricular involvement or hemodynamic compromise. DISCUSSION The patient we presented, was sent to Cardiology due to heart failure symptoms. Acute heart failure as well as embolisation and life-threatening arrythmias are typical manifestations of PCL. As reported in the literature, our case was a diffuse large B-cell lymphoma, which is the most frequent subtype. Dysphagia, exertional dyspnoea and constitutional symptoms can be present in early stages, as our patient referred. The main strength of this case is based on the quick diagnosis and early treatment. In contrary to what is reported, the overall survival was excellent, and to date the patient is still alive with no signs of relapse. Although TTE sensitivity is 55-60%, it has a key role in the diagnosis, which was supported later on MRI. Right chambers (specially right atria) are more typically involved than the left heart, including right venous drainage. Early systemic chemotherapy can achieve a high response rate and improve survival. Abstract P185 Figure. Img1

scholarly journals Diagnostic challenge in primary cardiac lymphoma: a case report

2020 ◽  
Vol 4 (5) ◽  
pp. 1-5
Author(s):  
Chonthicha Tanking ◽  
Supawat Ratanapo
Keyword(s):  
Case Report ◽  
Immunohistochemical Staining ◽  
Treatment Plan ◽  
B Cell Lymphoma ◽  
Large Mass ◽  
Pathology Report ◽  
Diagnostic Challenge ◽  
Leukaemia Virus ◽  
Cardiac Lymphoma ◽  
Primary Cardiac Lymphoma

Abstract Background Primary cardiac lymphoma is an extra-nodal non-Hodgkin’s lymphoma, which usually responds well to chemotherapy. The disease has high mortality rate unless it is recognized and treated in time. Tissue pathology is crucially the diagnosis gold standard for treatment plan. This is a case report of an elderly female who presented with a huge right-sided cardiac tumour obstructing tricuspid flow. Case summary An 81-year-old Asian female presented with clinical right-sided heart failure. Echocardiogram showed a large mass compressing and obliterating the right atrium. Trans-jugular tissue biopsy was performed. Initial pathology report was consistent with an angiosarcoma, based on an expression of Fli-1 (Friend leukaemia virus integration 1) from immunohistochemical staining. She died shortly after refusal to surgery. Autopsy was performed with diagnosis change to a diffuse large B-cell lymphoma (DLBCL) after tissue pathology. Discussion Primary cardiac lymphoma is extremely rare. Adequate tissue and proper immunohistochemical staining are mandatory for treatment plan. Besides an angiosarcoma, DLBCL should be considered in the differential diagnosis of Fli-1 positive tissue cardiac mass.

scholarly journals Imaging Findings of Lipomatous Hypertrophy of the Interventricular Septum: A Case Report

2021 ◽  
Vol 14 ◽  
pp. 117954762110248
Author(s):  
Selvakumar Subbaraman ◽  
Seena Cheppala Rajan ◽  
Saveetha Veeraiyan ◽  
Paarthipan Natarajan
Keyword(s):  
Cardiac Tumor ◽  
Interventricular Septum ◽  
Cardiac Tumors ◽  
Resonance Imaging ◽  
Rare Form ◽  
Cardiac Lipoma ◽  
Lipomatous Hypertrophy ◽  
Benign Cardiac Tumor ◽  
Primary Cardiac Tumors

Primary cardiac tumors are rare. We report a case of lipomatous hypertrophy of the interventricular septum in a healthy, asymptomatic, 16 year old female, diagnosed initially by echocardiogram. Non contrast Computed tomography (CT) and Cardiac magnetic resonance imaging (CMR) were also performed to confirm the diagnosis of this rarely reported condition. Lipomatous hypertrophy of the interventricular septum is a rare form of benign cardiac tumor characterized by the proliferation of adipose tissue (fat) in the interventricular septum. This clinical entity has to be differentiated from cardiac lipoma which is a benign, encapsulated tumor. CMR helps is differentiating between the 2 conditions. As the lesion was neither causing compression of the ventricle nor obstruction to blood flow, she was managed conservatively and advised follow up.

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