scholarly journals Minimally Invasive Alveolar Ridge Preservation Utilizing anIn SituHardeningβ-Tricalcium Phosphate Bone Substitute: A Multicenter Case Series

2016 ◽  
Vol 2016 ◽  
pp. 1-12 ◽  
Author(s):  
Minas D. Leventis ◽  
Peter Fairbairn ◽  
Ashish Kakar ◽  
Angelos D. Leventis ◽  
Vasileios Margaritis ◽  
...  

Ridge preservation measures, which include the filling of extraction sockets with bone substitutes, have been shown to reduce ridge resorption, while methods that do not require primary soft tissue closure minimize patient morbidity and decrease surgical time and cost. In a case series of 10 patients requiring single extraction,in situhardening beta-tricalcium phosphate (β-TCP) granules coated with poly(lactic-co-glycolic acid) (PLGA) were utilized as a grafting material that does not necessitate primary wound closure. After 4 months, clinical observations revealed excellent soft tissue healing without loss of attached gingiva in all cases. At reentry for implant placement, bone core biopsies were obtained and primary implant stability was measured by final seating torque and resonance frequency analysis. Histological and histomorphometrical analysis revealed pronounced bone regeneration (24.4 ± 7.9% new bone) in parallel to the resorption of the grafting material (12.9 ± 7.7% graft material) while high levels of primary implant stability were recorded. Within the limits of this case series, the results suggest thatβ-TCP coated with polylactide can support new bone formation at postextraction sockets, while the properties of the material improve the handling and produce a stable and porous bone substitute scaffoldin situ, facilitating the application of noninvasive surgical techniques.

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Peter Fairbairn ◽  
Minas Leventis ◽  
Chas Mangham ◽  
Robert Horowitz

This case report highlights the use of a novel in situ hardening synthetic (alloplastic), resorbable, bone grafting material composed of beta tricalcium phosphate and calcium sulfate, for alveolar ridge preservation. A 35-year-old female patient was referred by her general dentist for extraction of the mandibular right first molar and rehabilitation of the site with a dental implant. The nonrestorable tooth was “atraumatically” extracted without raising a flap, and the socket was immediately grafted with the synthetic biomaterial and covered with a hemostatic fleece. No membrane was used, and the site was left uncovered without obtaining primary closure, in order to heal by secondary intention. After 12 weeks, the architecture of the ridge was preserved, and clinical observation revealed excellent soft tissue healing without loss of attached gingiva. At reentry for placement of the implant, a bone core biopsy was obtained, and primary implant stability was measured by final seating torque and resonance frequency analysis. Histological analysis revealed pronounced bone regeneration while high levels of primary implant stability were recorded. The implant was successfully loaded 12 weeks after placement. Clinical and radiological follow-up examination at two years revealed stable and successful results regarding biological, functional, and esthetic parameters.


2018 ◽  
Vol 6 (3) ◽  
pp. 27 ◽  
Author(s):  
Minas Leventis ◽  
George Agrogiannis ◽  
Peter Fairbairn ◽  
Orestis Vasiliadis ◽  
Danai Papavasileiou ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kwantae Noh ◽  
Daniel S. Thoma ◽  
Jung-Chul Park ◽  
Dong-Woon Lee ◽  
Seung-Yun Shin ◽  
...  

AbstractInformation regarding profilometric changes at a soft tissue level following implant placement with different protocols is insufficient. Therefore, this study aimed to comparatively investigate the profilometric tissue changes with respect to late implant placement following alveolar ridge preservation (LP/ARP) and early implantation (EP) in periodontally compromised non-molar extraction sites. Sixteen patients were randomly assigned to the following groups: implant placement 4 months post-ARP (group LP/ARP) and tooth extraction and implant placement 4–8 weeks post-extraction (group EP). Dental impressions were obtained immediately after final prosthesis insertion and at 3, 6, and 12 months. At the time of implant placement, bone augmentation was performed in the majority of the patients. Profilometric changes of the tissue contour were minimal between the final prosthesis insertion and 12 months in the mid-facial area (0.04–0.35 mm in group LP/ARP, 0.04–0.19 mm in group EP). The overall tissue volume increased in both groups (1.70 mm3 in group LP/ARP, 0.96 mm3 in group EP). In conclusion, LP/ARP and EP led to similar stability of the peri-implant tissue contour between the final prosthesis insertion and at 12 months. Moreover, the change of peri-implant tissue on the soft tissue level was minimal in both modalities.


2013 ◽  
Vol 65 (2) ◽  
pp. 429-437 ◽  
Author(s):  
M. Jurisic ◽  
Milica Manojlovic-Stojanoski ◽  
M. Andric ◽  
V. Kokovic ◽  
Vesna Danilovic ◽  
...  

Biphasic calcium phosphates (BCP) are widely used in alveolar ridge regeneration as a porous scaffold for new bone formation. The aim of this case series was to evaluate the regenerative effect of the combination of BCP and polylactide-co-glycolide (PLGA) which can serve as a barrier membrane during bone regeneration. The study included five patients. Four months into the healing period, bone samples were collected for histological and morphometric analyses. The results of morphometric analysis showed that newly formed bone represented 32.2 ? 6.8% of the tissue, 31.9 ? 8.9% was occupied by residual graft and 35.9 ? 13.5% by soft tissue. Active osteogenesis was seen around the particles of the graft. The particles were occupied mostly by immature woven bone and connective tissue. The quality and quantity of newly formed bone, after the use of BCP/PLGA for ridge preservation, can be adequate for successful implant therapy after tooth extraction.


2018 ◽  
Vol 23 (03) ◽  
pp. 424-429 ◽  
Author(s):  
Akira Ikumi ◽  
Toru Funayama ◽  
Toshinori Tsukanishi ◽  
Hiroshi Noguchi ◽  
Masashi Yamazaki

Unidirectional porous β-tricalcium phosphate (UDPTCP; Affinos®, Kuraray, Tokyo, Japan) has been in clinical use since 2015. Animal studies have confirmed the excellent potential of UDPTCP with regard to bone formation and material absorption. We present the first three clinical cases using UDPTCP as a bone substitute after curettage of benign bone tumors of the hand. All three patients were males, 29-, 30- and 81-years-old, two having a diagnosis of enchondroma and the other, a bone ganglion, with a pathological fracture identified in one case. Over a mean follow-up of 10 months, all patients achieved satisfactory clinical result, with no adverse events of UDPTCP noted. Radiographic evidence of good bone formation and material absorption was observable over the postoperative course. UDPTCP provided satisfactory clinical results, with good biocompatibility and fast resorption characteristics. Therefore, UDPTCP could provide a safe and reliable filling substitute for bone defects following curettage of small bone tumors.


2020 ◽  
Vol 9 (2) ◽  
Author(s):  
Anabelle Dias Ribeiro ◽  
Julliana Cariry Palhano Freire ◽  
Jaqueline Oliveira Barreto ◽  
Eduardo Dias Ribeiro ◽  
Ronaldo Lira Júnior ◽  
...  

A anatomia do tecido mole peri-implantar é semelhante à do dente natural, uma vez que apresenta epitélio juncional e tecido conjuntivo. O selamento peri-implantar é estabelecido pela mucosa ceratinizada que previne a migração apical da margem gengival, mantendo a arquitetura tecidual e estética vermelha ao redor dos implantes osseointegráveis. O presente trabalho objetivou relatar um caso clínico de reconstrução de tecido mole previamente a cirurgia óssea reconstrutiva para a instalação de implante osseointegrável. Após a reconstrução do tecido mole observou-se que houve um satisfatório ganho de altura e espessura tecidual. Foi obtido um volume tecidual suficiente para regularização do zênite gengival e considerável volume de mucosa ceratinizada foi obtida previamente a cirurgia reconstrutiva.Descritores: Implantes Dentários; Periodontia; Reabilitação Bucal.ReferênciasMutthineni RB, Dudala RB, Ramisetty A. Esthetic root coverage with double papillary subepithelial connective tissue graft: a case report. Case Rep Dent. 2014;2014:509319.Peñarrocha MA, Carrillo C, Boronat A,Martí EM. Level of satisfaction in patients with maxillary mull-arch fixed protheses: zigomatic versus convencional implants. Int J Oral Maxillofac Implants. 2007;22(5):769-73.Ponsi J, Lahti S, Rissanen H, Oikarinen K. Change in subjective oral health after single dental implant treatment. Int J Oral Maxillofac Implants. 2011;26(3):571-77.Man Y, Wang Y, Qu Y, Wang P, Gong P. A palatal roll envelope technique for peri-implant mucosa reconstruction: a prospective case series study. Int J Oral Maxillofac Surg. 2013;42(5):660-65.Schneider D, Grunder U, Ender A, Hämmerle CH, Jung RE. Volume gain and stability of peri-implant tissue following bone and soft tissue augmentation: 1-year results from a prospective cohort study. Clin Oral Implants Res. 2011;22(1):28-37.Evans CD, Chen ST. Esthetic outcomes of immediate implant placements. Clin Oral Implants Res. 2008;19(1):73-80.Grover HS, Yadav A, Yadav P, Nanda P. Free gingival grafting to increase the zone of Keratinized tissue around implants. Int J Oral Implant Clinical Res. 2011;2(2):117-20.Almeida JM, Novaes VN, Faleiros PL, Macarimi VC, Bosco AF, Theodoro LH et al. Aumento de gengiva ceratinizada em mucosa peri-implantar. Rev odontol UNESP. 2012;41(5):365-69.Langer B, Langer L. Overlapped flap: a surgical modification for implant fixture installation. Int J Periodontics Restorative Dent. 1990;10(3):208-15.Raghoebar GM, Meijer HJA, van Minnen B, Vissink A. Immediate Reconstruction of Failed Implants in the Esthetic Zone Using a Flapless Technique and Autogenous Composite Tuberosity Graft. J Oral Maxillofac Surg. 2018;76(3):528-33.Chung DM, Oh TJ, Shotwell JL, Misch CE, Wang HL. Significance of keratinized mucosa in maintenance of dental implants with different surfaces. J Periodontol. 2006;77(8):1410-20.Park JC , Yang KB, Choi Y , Kim YT , Jung UW , Kim CS et al. A simple approach to preserve keratinized mucosa around implants using a pre-fabricated implant-retained stent: a report of two cases. J Periodontal Implant Sci. 2010; 40(4):194-200.Wennström JL, Bengazi F, Lekholm U. The influence of the masticatory mucosa on the peri-implant soft tissue condition. Clin Oral Implants Res. 1994;5(1):1-8. Bengazi F, Wennström JL, Lekholm U. Recession of the soft tissue margin at oral implants. A 2-year longitudinal prospective study. Clin Oral Implants Res. 1996;7(4):303-10.Bouri A Jr, Bissada N, Al-Zahrani MS, Faddoul F, Nouneh I. Width of keratinized gingiva and the health status of the supporting tissues around dental implants. Int J Oral Maxillofac Implants. 2008;23(2):323-26.Fu JH, Su CY, Wang HL. Esthetic soft tissue management for teeth and implants. J Evid Based Dent Pract. 2012;12(3 Suppl):129-42.Marquez IC. The role of keratinized tissue and attached gingiva in maintaining periodontal/peri-implant health. Gen Dent. 2004;52(1):74-9.


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