scholarly journals Characterization of Enhancing MS Lesions by Dynamic Texture Parameter Analysis of Dynamic Susceptibility Perfusion Imaging

2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Rajeev K. Verma ◽  
Johannes Slotboom ◽  
Cäcilia Locher ◽  
Mirjam R. Heldner ◽  
Christian Weisstanner ◽  
...  
Keyword(s):  
Perfusion Imaging ◽  
Parameter Analysis ◽  
Dynamic Susceptibility ◽  
Imaging Features ◽  
Dynamic Texture ◽  
Feature Maps ◽  
Texture Parameter ◽  
Mr Perfusion Imaging ◽  
Texture Parameters ◽  
Main Effects

Purpose. The purpose of this study was to investigate statistical differences with MR perfusion imaging features that reflect the dynamics of Gadolinium-uptake in MS lesions using dynamic texture parameter analysis (DTPA).Methods. We investigated 51 MS lesions (25 enhancing, 26 nonenhancing lesions) of 12 patients. Enhancing lesions (n=25) were prestratified into enhancing lesions with increased permeability (EL+;n=11) and enhancing lesions with subtle permeability (EL−;n=14). Histogram-based feature maps were computed from the raw DSC-image time series and the corresponding texture parameters were analyzed during the inflow, outflow, and reperfusion time intervals.Results. Significant differences (p<0.05) were found between EL+ and EL− and between EL+ and nonenhancing inactive lesions (NEL). Main effects between EL+ versus EL− and EL+ versus NEL were observed during reperfusion (mainly in mean and standard deviation (SD): EL+ versus EL− and EL+ versus NEL), while EL− and NEL differed only in their SD during outflow.Conclusion. DTPA allows grading enhancing MS lesions according to their perfusion characteristics. Texture parameters of EL− were similar to NEL, while EL+ differed significantly from EL− and NEL. Dynamic texture analysis may thus be further investigated as noninvasive endogenous marker of lesion formation and restoration.

scholarly journals Characterization of Microcirculation in Multiple Sclerosis Lesions by Dynamic Texture Parameter Analysis (DTPA)

PLoS ONE ◽  
2013 ◽  
Vol 8 (7) ◽  
pp. e67610 ◽  
Author(s):  
Rajeev Kumar Verma ◽  
Johannes Slotboom ◽  
Mirjam Rahel Heldner ◽  
Frauke Kellner-Weldon ◽  
Raimund Kottke ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Parameter Analysis ◽  
Dynamic Texture ◽  
Texture Parameter

scholarly journals Acute-Onset Migrainous Aura Mimicking Acute Stroke: MR Perfusion Imaging Features

2012 ◽  
Vol 33 (8) ◽  
pp. 1546-1552 ◽  
Author(s):  
D. Floery ◽  
M.R. Vosko ◽  
F.A. Fellner ◽  
C. Fellner ◽  
C. Ginthoer ◽  
...  
Keyword(s):  
Acute Stroke ◽  
Perfusion Imaging ◽  
Acute Onset ◽  
Imaging Features ◽  
Mr Perfusion ◽  
Mr Perfusion Imaging

scholarly journals Correction: Characterization of Microcirculation in Multiple Sclerosis Lesions by Dynamic Texture Parameter Analysis (DTPA)

PLoS ONE ◽  
2013 ◽  
Vol 8 (7) ◽  
Author(s):  
Rajeev Kumar Verma ◽  
Johannes Slotboom ◽  
Mirjam Rachel Heldner ◽  
Frauke Kellner-Weldon ◽  
Raimund Kottke ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Parameter Analysis ◽  
Dynamic Texture ◽  
Texture Parameter

scholarly journals A Case-Based Review of Cerebral Venous Infarcts With Perfusion Imaging and Comparison to Arterial Ischemic Stroke

2021 ◽  
Vol 1 ◽  
Author(s):  
Anna Y. Li ◽  
Elizabeth Tong ◽  
Vivek S. Yedavalli
Keyword(s):  
Perfusion Imaging ◽  
Adult Population ◽  
Neurological Complications ◽  
Imaging Features ◽  
Arterial Ischemic Stroke ◽  
Mr Perfusion Imaging ◽  
Imaging Characteristics ◽  
Life Threatening ◽  
Venous Infarcts ◽  
Case Based

Cerebral venous thrombosis (CVT) and cerebral venous infarcts (CVI) are diagnostic dilemmas secondary to their rarity, non-specific symptomatology at presentation, and variable imaging features. Despite its relatively infrequence, CVT is particularly prevalent in the younger adult population and is a potentially life-threatening disease with devastating neurological complications if not addressed in a timely manner. However, when treated promptly, CVT has the potential for a more reversible course and favorable prognosis than arterial ischemic strokes (AIS). The pathophysiology of CVI is distinct from that of AIS and is closely related to its potentially reversible nature. Familiarity with the conventional and variant venous anatomy, as well as the temporal evolution of imaging findings, is crucial in establishing diagnostic confidence. The use of MR perfusion imaging (MRP) and arterial spin-labeling (ASL) can potentially aid in the diagnosis of CVT/CVI via characterization of cerebral blood flow. The presence and extent of a cerebral perfusion deficit on either CT or MRI may play a role in clinical outcomes for patients with CVT, although future larger studies must be performed. This review presents a case-based overview focusing on the classic imaging characteristics of CVT and CVI in conjunction with bolus MRP and ASL findings in the adult population.

Dynamic susceptibility MR perfusion imaging of the brain: not a question of contrast agent molarity

2021 ◽  
Author(s):  
Valentina Panara ◽  
Piero Chiacchiaretta ◽  
Matteo Rapino ◽  
Valerio Maruotti ◽  
Matteo Parenti ◽  
...  
Keyword(s):  
Contrast Agent ◽  
Perfusion Imaging ◽  
Dynamic Susceptibility ◽  
Mr Perfusion ◽  
Mr Perfusion Imaging ◽  
The Brain
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