Clinical Experience with the PillCam Patency Capsule prior to Video Capsule Endoscopy: A Real-World Experience

Background.In patients with known or suspected risk factors for gastrointestinal stenosis, the PillCam patency capsule (PC) is given before a video capsule endoscopy (VCE) in order to minimize the risk of capsule retention (CR). CR is considered unlikely upon excretion of the PC within 30 hours, excretion in an undamaged state after 30 hours, or radiological projection to the colon.Methods.We performed a retrospective analysis of 38 patients with risk factors for CR, who received a PC from 02/2013 to 04/2015 at Klinikum Augsburg.Results.Sixteen of our 38 patients observed a natural excretion after a mean time of 34 hours past ingestion. However, only 8 patients observed excretion within 30 hours, as recommended by the company. In 20 patients passage of the PC into the colon was shown via RFID-scan or radiological imaging (after 33 and 45 hours, resp.). Only 2 patients showed a pathologic PC result. In consequence, 32 patients received the VCE; no CR was observed.Conclusion.Our data indicates that a VCE could safely be performed even if the PC excretion time is longer than 30 hours and the excreted PC was not screened for damage.

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Sa1743 Efficacy of Patency Capsule and Abdominal Xray in Predicting Passage of Video Capsule Endoscopy to the Cecum in Patients Suspected of Potential Capsule Retention

Gastrointestinal Endoscopy ◽

10.1016/j.gie.2012.04.263 ◽

2012 ◽

Vol 75 (4) ◽

pp. AB261

Author(s):

Thomas H. Smith ◽

Achuthan Sourianarayanane ◽

John J. Vargo ◽

Jan Santisi ◽

Cindy Heinlein ◽

...

Keyword(s):

Capsule Endoscopy ◽

Video Capsule Endoscopy ◽

Patency Capsule ◽

Capsule Retention

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Capsule Retentions and Incomplete Capsule Endoscopy Examinations: An Analysis of 2300 Examinations

Gastroenterology Research and Practice ◽

10.1155/2012/518718 ◽

2012 ◽

Vol 2012 ◽

pp. 1-7 ◽

Cited By ~ 76

Author(s):

Charlotte M. Höög ◽

Lars-Åke Bark ◽

Juan Arkani ◽

Jacob Gorsetman ◽

Olle Broström ◽

...

Keyword(s):

Risk Factors ◽

Crohn’S Disease ◽

Crohn's Disease ◽

Capsule Endoscopy ◽

Male Gender ◽

Large Series ◽

Older Age ◽

Safe Procedure ◽

Capsule Retention

Aim. To evaluate capsule endoscopy in terms of incomplete examinations and capsule retentions and to find risk factors for these events.Material and Methods. This retrospective and consecutive study includes data from 2300 capsule enteroscopy examinations, performed at four different hospitals in Stockholm, Sweden from 2003 to 2009.Results. The frequency of incomplete examinations was 20%. Older age, male gender, suspected, and known Crohn's disease were risk factors for an incomplete examination. The PillCam capsule had the highest rate of completed examinations. Capsule retention occurred in 1.3% (). Risk factors for capsule retention were known Crohn's disease and suspected tumor. Complications of capsule retention were acute obstructive symptoms in six patients and one death related to complications after acute surgical capsule retrieval.Conclusion: Capsule endoscopy is considered a safe procedure, although obstructive symptoms and serious complications due to capsule retention can be found in a large series of patients.

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Clinical Utility of Patency Capsule in Pediatric Video Capsule Endoscopy

The American Journal of Gastroenterology ◽

10.14309/00000434-201510001-02368 ◽

2015 ◽

Vol 110 ◽

pp. S983-S984

Author(s):

Stephen Nanton ◽

Joelle Roskens ◽

Sarah Feit

Keyword(s):

Capsule Endoscopy ◽

Clinical Utility ◽

Video Capsule Endoscopy ◽

Patency Capsule

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Video capsule endoscopy in pediatric patients with Crohn’s disease: a single-center experience of 180 procedures

Therapeutic Advances in Gastroenterology ◽

10.1177/1756284818758929 ◽

2018 ◽

Vol 11 ◽

pp. 175628481875892 ◽

Cited By ~ 3

Author(s):

Artur Nemeth ◽

Daniel Agardh ◽

Gabriele Wurm Johansson ◽

Henrik Thorlacius ◽

Ervin Toth

Keyword(s):

Crohn’S Disease ◽

Crohn's Disease ◽

Capsule Endoscopy ◽

Pediatric Patients ◽

Video Capsule Endoscopy ◽

Single Center ◽

Recording Time ◽

Single Center Experience ◽

Capsule Retention ◽

The Impact

Background Video capsule endoscopy (VCE) is a noninvasive method enabling excellent visualization of the small bowel (SB) mucosa. The aim of this study was to examine the impact and safety of VCE performed in children and adolescents with suspected or established Crohn’s disease (CD). Methods A total of 180 VCE examinations in 169 consecutive patients conducted in 2003–14 in a single center were retrospectively analyzed. The median age was 13 years (range 3–17 years) and indications for VCE were suspected (125 cases, 69%) and established (55 cases, 31%) CD. VCE was performed with a PillCam SB (Given Imaging, Yokneam, Israel) VCE system with 8–12 h of registration without bowel preparation. Results A total of 154 of 180 (86%) patients swallowed the capsule and 26 (14%) had the capsule endoscopically placed in the duodenum. Patency capsule examination was performed in 71 cases prior to VCE to exclude SB obstruction. VCE detected findings consistent with SB CD in 71 (40%) examinations and 17 (9%) procedures showed minor changes not diagnostic for CD. A total of 92 (51%) examinations displayed normal SB mucosa. The capsule did not reach the colon within the recording time in 30 (17%) procedures and were defined as incomplete examinations. A change in diagnosis or therapy was recommended in 56 (31%) patients based on VCE results. Capsule retention occurred in one patient. Conclusions VCE is a safe method in children with suspected or established CD. VCE often leads to a definitive diagnosis and has a significant impact on the clinical management of pediatric patients with CD.

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M2A Patency Capsule Prior to Video Capsule Endoscopy in Patients with Morphological Small Bowel Strictures

Gastrointestinal Endoscopy ◽

10.1016/s0016-5107(04)00700-x ◽

2004 ◽

Vol 59 (5) ◽

pp. P145

Author(s):

Cristiano Spada ◽

Gianluca Spera ◽

Maria Elena Riccioni ◽

Andrea Tringali ◽

Pietro Familiari ◽

...

Keyword(s):

Small Bowel ◽

Capsule Endoscopy ◽

Video Capsule Endoscopy ◽

Patency Capsule

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Risk Factors of Malignant Glaucoma Occurrence after Glaucoma Surgery

Journal of Ophthalmology ◽

10.1155/2017/9616738 ◽

2017 ◽

Vol 2017 ◽

pp. 1-6 ◽

Cited By ~ 5

Author(s):

Karolina Krix-Jachym ◽

Tomasz Żarnowski ◽

Marek Rękas

Keyword(s):

Risk Factors ◽

Retrospective Analysis ◽

Postoperative Period ◽

Glaucoma Surgery ◽

Iridocorneal Angle ◽

Primary Surgery ◽

Malignant Glaucoma ◽

Primary Glaucoma ◽

Mean Time ◽

Type Of Surgery

Purpose. The aim of this study was twofold: first, to evaluate the predisposing factors for occurrence of malignant glaucoma and second, to compare frequency of malignant glaucoma depending on the type of primary glaucoma surgery. Methods. Retrospective analysis was performed in 1689 consecutive patients who underwent glaucoma surgery alone or combined with phacoemulsification. Data collected included the type of surgery, width of the filtration angle, presence or absence of malignant glaucoma in the postoperative period, and time from the primary surgery to malignant glaucoma occurrence. Results. Malignant glaucoma occurred in 22 eyes that amounted to 1.3% of cases among all surgery performed. Mean time from glaucoma surgery to malignant glaucoma occurrence was 61.4 ± 190.5 days. Among patients with penetrating surgery, malignant glaucoma occurred in 2.3% of patients, whereas after nonpenetrating operations, such complication was not found (p=0.00004). Malignant glaucoma occurred more often in patients with shallow iridocorneal angle (p=0.0013). Conclusions. The risk of malignant glaucoma development is associated with penetrating characteristic of glaucoma surgery, after which this complication appears and its occurrence is higher in eyes with shallow iridocorneal angle. The risk of malignant glaucoma after trabeculectomy compared to iridencleisis as well as after phacotrabeculectomy compared to phacoiridencleisis is equivalent.

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Usefulness of patency capsule prior to small-bowel capsule endoscopy in clinical practice: Validity of the modified method of patency judgement

10.21203/rs.3.rs-951571/v1 ◽

2021 ◽

Author(s):

Takahiro Miyazu ◽

Satoshi Osawa ◽

Satoshi Tamura ◽

Shinya Tani ◽

Natsuki Ishida ◽

...

Keyword(s):

Clinical Practice ◽

Small Bowel ◽

Capsule Endoscopy ◽

Patency Rate ◽

The Body ◽

Coating Film ◽

X Ray ◽

Modified Method ◽

Patency Capsule ◽

Capsule Retention

Abstract In 2012, Japan approved the use of a tag-less patency capsule (PC), which evaluates gastrointestinal patency before small-bowel capsule endoscopy (SBCE). This study aimed to evaluate the validity of our modification on the passage criteria for this PC in clinical practice. We retrospectively enrolled 326 consecutive patients who underwent PC examination before SBCE. If X-ray could not reveal the PC in the body during the judgement time (30–33 h after ingestion), we defined it as ‘estimated patency’ and performed SBCE. We employed plain computed tomography (CT) for the second judgement, as needed. The overall patency rate was 95.1%. By X-ray, 41 (12.6%) patients were judged to have ‘estimated patency’, and SBCE could be safely performed. Plain CT judgement was necessary in 32.5%. One PC case had a residual coating film associated with stenosis in a patient with Crohn’s disease (CD), and one (0.3%) SBCE case had capsule retention resulting from false CT judgement. Multivariate analysis revealed that established CD and inpatient were factors related to patency loss. In conclusion, PC is useful for examining gastrointestinal patency, keeping in mind CT misjudgement. If PC was not found in the body via X-ray, performing SBCE as ‘estimated patency’ seemed appropriate.

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Premature dissolution of the Agile patency device: implications for capsule endoscopy

Frontline Gastroenterology ◽

10.1136/flgastro-2018-101112 ◽

2018 ◽

Vol 10 (3) ◽

pp. 217-221

Author(s):

Nicholas Wray ◽

Ailish Healy ◽

Vicky Thurston ◽

Melissa Fay Hale ◽

Reena Sidhu ◽

...

Keyword(s):

Small Bowel ◽

Capsule Endoscopy ◽

Intestinal Transit ◽

Radiological Imaging ◽

Radiological Evidence ◽

Radiofrequency Identification ◽

Capsule Retention ◽

Radiofrequency Signal ◽

Do So

BackgroundThe main risk of capsule endoscopy is retention of the capsule behind a stricture. Passage of an intact Agile patency device (Medtronic, Dublin, Ireland) through the small bowel is widely used to ensure luminal patency, although capsule retention has occurred in patients who have had a reassuring patency study. The device is designed to remain intact for at least 30 hours postingestion, such that loss of signal from the radiofrequency identification tag contained within, or absence of the device on radiological imaging, implies unimpeded intestinal transit.AimTo identify the rate of premature dissolution (<30 hours postingestion) of the Agile patency device.MethodsOutcomes of all consecutive patients having an Agile patency device were analysed.ResultsPremature dissolution of the patency device occurred in 5 of 307 patients, an incidence of 1.3%. This was recognised by the detection of a persistent radiofrequency signal after radiological imaging had failed to identify the patency device, prompting a careful search for the radiofrequency tag on the CT scout film. The tag was difficult to detect because of an oblique lie making it appear smaller than its 13×3 mm size and confusion with intra-abdominal or other metallic fragments.ConclusionsIn the absence of radiological evidence of an intact Agile patency device, premature dissolution should be suspected in patients registering a persistent radiofrequency signal and confirmed by identifying the radiofrequency identification tag. Failure to do so might result in false reassurance that capsule endoscopy could be performed without risk of retention.

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