scholarly journals Red Blood Cell Distribution Width: A Novel Predictive Indicator for Cardiovascular and Cerebrovascular Diseases

2017 ◽  
Vol 2017 ◽  
pp. 1-23 ◽  
Author(s):  
Ning Li ◽  
Heng Zhou ◽  
Qizhu Tang
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Complete Blood Count ◽  
Predictive Marker ◽  
Biochemical Parameter ◽  
Cerebrovascular Diseases ◽  
Deficiency Anemia ◽  
Cell Distribution ◽  
Distribution Width ◽  
Red Blood Cell Distribution

The red blood cell distribution width (RDW) obtained from a standard complete blood count (CBC) is a convenient and inexpensive biochemical parameter representing the variability in size of circulating erythrocytes. Over the past few decades, RDW with mean corpuscular volume (MCV) has been used to identify quite a few hematological system diseases including iron-deficiency anemia and bone marrow dysfunction. In recent years, many clinical studies have proved that the alterations of RDW levels may be associated with the incidence and prognosis in many cardiovascular and cerebrovascular diseases (CVDs). Therefore, early detection and intervention in time of these vascular diseases is critical for delaying their progression. RDW as a new predictive marker and an independent risk factor plays a significant role in assessing the severity and progression of CVDs. However, the mechanisms of the association between RDW and the prognosis of CVDs remain unclear. In this review, we will provide an overview of the representative literatures concerning hypothetical and potential epidemiological associations between RDW and CVDs and discuss the underlying mechanisms.

scholarly journals A Novel Parameter for Predicting Therapeutic Response in Iron Deficiency Anemia: Red Blood Cell Distribution Width

2019 ◽  
Vol 8 (3) ◽  
pp. 107-112
Author(s):  
Aslı Korur ◽  
Didar Yanardag Acik ◽  
Soner Solmaz ◽  
Cigdem Gereklioglu ◽  
Suheyl Asma ◽  
...  
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Blood Count ◽  
Complete Blood Count ◽  
Reticulocyte Count ◽  
Iron Therapy ◽  
Deficiency Anemia ◽  
Cell Distribution ◽  
Distribution Width ◽  
Red Blood Cell Distribution

Aim: Anemia is a public health problem worldwide. Cost effectiveness and efficient use of resources are vitally important. Red blood cell distribution width, which can be obtained from a standard complete blood count, is a measure of the variability in size of circulating erythrocytes. The present study was performed to investigate whether red blood cell distribution width can be used to predict response to iron therapy. Methods: This study was conducted in 50 patients admitted to hematology and family medicine clinics. Complete blood count and reticulocyte count were determined on day 5; complete blood count was examined 1 month after commencement of therapy. Results: Statistically significant differences were detected between hemoglobin levels and red blood cell distribution width values at the time of diagnosis and on day 5 and after 1 month of therapy. A significant positive correlation was found between the increase in red blood cell distribution width and the increase in hemoglobin. Conclusion: Red blood cell distribution width may be used in place of reticulocyte count to predict response to iron therapy. Red blood cell distribution width is the best biomarker for this purpose as a component of complete blood count, and therefore it may be accepted as superior to reticulocyte count.

scholarly journals Red blood cell distribution width and iron deficiency anemia among pregnant Sudanese women

2012 ◽  
Vol 7 (1) ◽  
pp. 168 ◽  
Author(s):  
Esam G Abdelrahman ◽  
Gasim I Gasim ◽  
Imad R Musa ◽  
Leana M Elbashir ◽  
Ishag Adam
Keyword(s):  
Iron Deficiency ◽  
Blood Cell ◽  
Iron Deficiency Anemia ◽  
Red Blood Cell ◽  
Deficiency Anemia ◽  
Cell Distribution ◽  
Distribution Width ◽  
Red Blood Cell Distribution

scholarly journals IRON DEFICIENCY ANEMIA

2018 ◽  
Vol 25 (05) ◽  
pp. 659-663
Author(s):  
Nathumal Maheshwari ◽  
Omperkash Khemani ◽  
Bilawal Hingorjo ◽  
Mehmood Shaikh ◽  
Siri Chand ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Blood Cell ◽  
Iron Deficiency Anemia ◽  
Red Blood Cell ◽  
Venous Blood ◽  
Deficiency Anemia ◽  
Cell Distribution ◽  
Cross Sectional ◽  
Distribution Width ◽  
Red Blood Cell Distribution

Objectives: To evaluate the predictive value of Red blood cell distribution width(RDW) for the iron deficiency anemia in children. Study Design: Cross sectional study. Placeand Duration: Department of Paediatrics, Layari General Hospital Shaheed Muhtrama BenazirBhutto Medical College from December 2015 to March 2016. Methodology: A sample of 100children (53 male and 47 female) was selected through non- probability (purposive sampling). 5ml venous blood was collected, 3 ml was shifted to EDTA containing vacutainers and remainingwas processed and centrifuged to separate sera. Complete blood counts and iron profile wereperformed. Data of cases and controls was analyzed on Statistix 10.0 software (USA) (P ≤0.05).Results: Severe iron deficiency and iron deficiency anemia were noted. Serum Iron, TIBC andFerritin were noted as 63.49±32.94 and 76.06±40.38 μg/dl, 468.7±142.2 and 445.5±135.2 μg/dl, & 36.2±14.12 and 43.2±13.5 ng/dl respectively. RDW proved a sensitivity and specificity of78% and 56% respectively (0.001). Conclusion: We observed severe iron deficiency anemia inchildren and Red blood cell distribution width showed high sensivity in predicting iron deficiencyanemia.

scholarly journals Red blood cell distribution width-standard deviation but not red blood cell distribution width-coefficient of variation as a potential index for the diagnosis of iron-deficiency anemia in mid-pregnancy women

2021 ◽  
Vol 16 (1) ◽  
pp. 1213-1218
Author(s):  
Yang Kai ◽  
Pan Ying ◽  
Yan Bo ◽  
Yu Furong ◽  
Chen Jin ◽  
...  
Keyword(s):  
Standard Deviation ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Roc Curves ◽  
Deficiency Anemia ◽  
Control Group ◽  
Cell Distribution ◽  
Distribution Width ◽  
Width Coefficient ◽  
Red Blood Cell Distribution

Abstract The aim of this study was to compare the diagnostic values of red blood cell distribution width-coefficient of variation (RDW-CV) and red blood cell distribution width-standard deviation (RDW-SD) in mid-pregnancy women with iron deficiency anemia (IDA). To obtain the results, 115 mid-pregnancy women with IDA, defined as the IDA group, and 142 healthy mid-pregnancy women, selected as the control group, were enrolled in this study. Hematological parameters and ferritin concentrations in the serum were analyzed. The efficiency of RDW-CV and RDW-SD to distinguish IDA from mid-pregnancy women was evaluated using receiver operating characteristic (ROC) curves. The RDW-SD value in the IDA group was significantly higher than that in the control group (p < 0.05), while the RDW-CV value did not differ between them (p = 0.84). Significantly negative correlations were found between RDW-CV (r = −0.297, p = 0.001), RDW-SD (r = −0.404, p = 0.000), and serum ferritin in the IDA group but not in the control group. For the diagnosis of IDA, RDW-CV and RDW-SD produced areas under the ROC curves of 0.58 and 0.84. To conclude, our results suggest that RDW-SD, but not RDW-CV, can be used as a diagnostic index of IDA for mid-pregnancy women.

scholarly journals Is Elevated Red Blood Cell Distribution Width Value a Prognostic Marker in Sepsis Patients?

2021 ◽  
pp. 42-46
Author(s):  
Sethuraj Selvaraj ◽  
A. Tumbanatham
Keyword(s):  
Blood Cell ◽  
Prognostic Marker ◽  
Red Blood Cell ◽  
Complete Blood Count ◽  
Predictive Score ◽  
Cell Distribution ◽  
Distribution Width ◽  
Independent Variable ◽  
Red Blood Cell Distribution ◽  
Morphology Changes

Sepsis and its complications are a common cause of infectious disease and death in worldwide. But the infection can be challenges to confirm and there is gold standard methods to confirm it. Red blood cell distribution width (RDW) value frequently measured at every complete blood count. In sepsis the RDW morphology changes are believed to be mainly related to prognosis. RDW has also been studied as an independent variable in different predictive score. We systematically review the articles can RDW be used as prognostic marker in patient with sepsis.

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