scholarly journals Safety and Efficacy of Small Bowel Examination by Capsule Endoscopy for Patients before Liver Transplantation

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Kawano Seiji ◽  
Takaki Akinobu ◽  
Iwamuro Masaya ◽  
Yasunaka Tetsuya ◽  
Kono Yoshiyasu ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Small Bowel ◽  
Transit Time ◽  
Capsule Endoscopy ◽  
High Rate ◽  
Clinical Trial Registry ◽  
Safety And Efficacy ◽  
Red Color ◽  
History Of ◽  
The Mean

Background and Aims. Gastrointestinal surveillance is a requirement prior to liver transplantation (LT), but small intestine examination is not generally undertaken. The aim of the present study was to evaluate the safety and efficacy of capsule endoscopy (CE) for patients with end-stage liver disease.Methods. 31 patients who needed LT were enrolled, and 139 patients who underwent CE over the same period of time acted as controls.Results. Frequency of successful achievement of evaluation of the full length of the small bowel, the mean gastric transit time, and the mean small bowel transit time were not significantly different between the two groups. Abnormalities in the small bowel were found in 26 patients. Comparative analysis revealed that history of EV rupture, history of EV treatment, red color sign of EV, and presence of PHG or HCC were significantly associated with patients with >2 two such findings (high score group).Conclusions. Small bowel examination by CE in patients before liver transplantation could be performed safely and is justified by the high rate of abnormal lesions detected particularly in patients with history of EV therapy or bleeding, red color sign, and presence of PHG or HCC. This study was registered in the UMIN Clinical Trial Registry (UMIN000008672).

scholarly journals Corrigendum to “Safety and Efficacy of Small Bowel Examination by Capsule Endoscopy for Patients before Liver Transplantation”

2017 ◽  
Vol 2017 ◽  
pp. 1-1
Author(s):  
Seiji Kawano ◽  
Akinobu Takaki ◽  
Masaya Iwamuro ◽  
Tetsuya Yasunaka ◽  
Yoshiyasu Kono ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Small Bowel ◽  
Capsule Endoscopy ◽  
Safety And Efficacy

The effect of macrogol administration on the quality of macroscopic images and transit time in canine capsule endoscopy

2014 ◽  
Vol 17 (4) ◽  
pp. 673-679 ◽  
Author(s):  
A. Rychlik ◽  
M. Nowicki ◽  
M. Kander ◽  
M. Szweda
Keyword(s):  
Small Bowel ◽  
Transit Time ◽  
Capsule Endoscopy ◽  
Large Bowel ◽  
Small Bowel Mucosa ◽  
The Mean ◽  
Colonoscopy Preparation ◽  
Mean Time ◽  
Bowel Mucosa

Abstract The present experiment evaluated the quality of macroscopic images and the mean time of capsule passage through different sections of the gastrointestinal tract in dogs subjected to different preparation protocols before capsule endoscopy. In the first examination, the colonoscopy preparation protocol was applied, and in the second examination, the animals were administered macrogol. The study revealed that macrogol administration before capsule endoscopy significantly improved the quality of macroscopic images. The colonoscopy preparation protocol may not support accurate visualization of the large bowel mucosa and, in selected patients, also the small bowel mucosa. Macrogol administration had no effect on capsule transit time through the alimentary canal. Capsules used in endoscopic evaluations of the small bowel in humans may have limited applications in macroscopic examinations of large bowel mucosa in dogs.

scholarly journals TO DETERMINE THE PREVALENCE OF LOW BONE MINERAL DENSITY (OSTEOPENIA AND OSTEOPOROSIS) IN INDIAN PATIENTS WITH CIRRHOSIS OF LIVER AWAITING LIVER TRANSPLANTATION AS PER CURRENTLY USED HOLOGIC DXA DATABASE

2021 ◽  
Vol 5 (4) ◽  
Author(s):  
Sharad Deshmukh ◽  
Suchita Deshmukh ◽  
Sarojni A Parameswran ◽  
P Pirmanayagam ◽  
N Murgan ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Liver Transplantation ◽  
Lumbar Spine ◽  
Bone Mineral ◽  
Mineral Density ◽  
Low Bone Mineral Density ◽  
Indian Patients ◽  
History Of ◽  
The Mean ◽  
Cirrhosis Of Liver

Background: Abnormalities in the bone metabolism observed in chronic liver disease are referred to as hepatic osteodystrophy. Osteoporosis and osteopenia are each part of this condition. Both conditions have a significant impact on morbidity, causing fractures that may result in chronic pain, long-lasting immobility, and deformity. Prevalence of fracture in patients with liver transplantation ranges from 15% - 65%. A high rate of fracturing is seen within the initial 1–2 years after transplantation. Aim: To determine the prevalence of low bone mineral density (osteopenia and osteoporosis) in Indian patients with cirrhosis of liver awaiting liver transplantation as per currently used Hologic DXA database Methods: This was a prospective observational study done at the department of gastroenterology and hepatology, Apollo Hospitals, Chennai from April 2011 to March 2013. All patients who fulfilled the inclusion criteria underwent detailed history taking, physical examination and relevant laboratory investigations. One hundred patients were selected for the scope of the study. Results: Sixty-eight per cent of patients were in the age group of 45 to 65 years. The mean age ± SD of the study subjects was 51.2 ± 9.7 years. The mean age for male patients was 50.5 ± 10.1 years, and for females was 54 ± 7.3 years. Cirrhosis was due to alcohol in 36% of the patients, viral hepatitis in 28% (HBV in 10% and HCV in 18%) patients. 42% were in Child’s class B, and the remaining 58% were in Child’s class C. MELD score was less than 20 in 62% patients. One third was diabetic; one third gave the history of backache. History of smoking was present in one fifth (20%) patients, and a history of fracture (most of them were traumatic) was present in 13% of patients. By using Hologic DXA database at the lumbar spine, osteopenia and osteoporosis were diagnosed in 44% and 38 % patients respectively. At the femoral neck, osteopenia and osteoporosis were diagnosed in 45% and 9% of patients. By using ICMR database at the lumbar spine, osteopenia and osteoporosis were diagnosed in 38% and 17% patients respectively. Similarly, at the femoral neck, osteopenia and osteoporosis were diagnosed in 34% and 5%. By using the Hologic DXA database, osteopenia and osteoporosis were diagnosed in 42% and 40 % patients. By using ICMR database, osteopenia and osteoporosis were diagnosed in 43% and 19% patients respectively. Conclusion: In light of the above results, the present study revealed a high prevalence of low bone mineral density (osteopenia and osteoporosis) in Indian patients with cirrhosis of liver awaiting liver transplantation. The lumbar spine was the most frequently and severely affected site in hepatic osteodystrophy. Keywords: Osteopenia, Osteoporosis, Low Bone Mineral Density, Liver Cirrhosis

Can the Small-Bowel Transit Time Influence the Diagnostic Yields of Capsule Endoscopy?

2006 ◽  
Vol 63 (5) ◽  
pp. AB158
Author(s):  
Young Jig Cho ◽  
Chang Duck Kim ◽  
Bora Keum ◽  
Youn Ho Kim ◽  
Hwi Kong ◽  
...  
Keyword(s):  
Small Bowel ◽  
Transit Time ◽  
Capsule Endoscopy ◽  
Small Bowel Transit ◽  
Small Bowel Transit Time

scholarly journals Aortoenteric fistula: a rare but critical cause of small bowel bleeding discovered on capsule endoscopy

2019 ◽  
Vol 12 (5) ◽  
pp. e230083
Author(s):  
Matt Davie ◽  
Diana E Yung ◽  
John N Plevris ◽  
Anastasios Koulaouzidis
Keyword(s):  
Small Bowel ◽  
Capsule Endoscopy ◽  
Abdominal Aortic Aneurysm Repair ◽  
Sudden Onset ◽  
Aortoenteric Fistula ◽  
Good Effect ◽  
Stent Grafting ◽  
Abdominal Aortic ◽  
History Of ◽  
Small Bowel Bleeding

A 78-year-old man attended for outpatient capsule endoscopy, to investigate a recent history of unexplained small bowel bleeding. His previous medical history included an abdominal aortic aneurysm repair 6 years ago. Soon after capsule ingestion, he experienced sudden onset abdominal pain and collapsed on hospital grounds. He was rapidly transferred to the emergency department as he was haemodynamically unstable, and a significant per rectum (PR) bleed was found on examination. The patient was quickly stabilised following fluid resuscitation. CT angiography was performed which did not show active bleeding. However, use of the real-time capsule viewer indicated a profuse active jejunal bleed originating from the aortic graft, suggestive of an aortoenteric fistula. The patient underwent emergency endovascular cuff placement, and subsequent endovascular abdominal aortic stent grafting, to good effect.

Automatic detection of different types of small-bowel lesions on capsule endoscopy images using a newly developed deep convolutional neural network

Endoscopy ◽  
2020 ◽  
Vol 52 (09) ◽  
pp. 786-791 ◽  
Author(s):  
Keita Otani ◽  
Ayako Nakada ◽  
Yusuke Kurose ◽  
Ryota Niikura ◽  
Atsuo Yamada ◽  
...  
Keyword(s):  
Neural Network ◽  
Small Bowel ◽  
Capsule Endoscopy ◽  
Characteristic Curve ◽  
Vascular Lesions ◽  
Single Type ◽  
Data Set ◽  
Normal Tissues ◽  
Computer Aided ◽  
The Mean

Abstract Background Previous computer-aided detection systems for diagnosing lesions in images from wireless capsule endoscopy (WCE) have been limited to a single type of small-bowel lesion. We developed a new artificial intelligence (AI) system able to diagnose multiple types of lesions, including erosions and ulcers, vascular lesions, and tumors. Methods We trained the deep neural network system RetinaNet on a data set of 167 patients, which consisted of images of 398 erosions and ulcers, 538 vascular lesions, 4590 tumors, and 34 437 normal tissues. We calculated the mean area under the receiver operating characteristic curve (AUC) for each lesion type using five-fold stratified cross-validation. Results The mean age of the patients was 63.6 years; 92 were men. The mean AUCs of the AI system were 0.996 (95 %CI 0.992 – 0.999) for erosions and ulcers, 0.950 (95 %CI 0.923 – 0.978) for vascular lesions, and 0.950 (95 %CI 0.913 – 0.988) for tumors. Conclusion We developed and validated a new computer-aided diagnosis system for multiclass diagnosis of small-bowel lesions in WCE images.

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