scholarly journals Prevalence of Low Birth Weight before and after Policy Change to IPTp-SP in Two Selected Hospitals in Southern Nigeria: Eleven-Year Retrospective Analyses

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Nneka U. Igboeli ◽  
Maxwell O. Adibe ◽  
Chinwe V. Ukwe ◽  
Nze C. Aguwa
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Prevention And Control ◽  
Intermittent Preventive Treatment ◽  
Preventive Treatment ◽  
Effective Prevention ◽  
Before And After ◽  
And Control ◽  
Sulphadoxine Pyrimethamine ◽  
In Pregnancy

Background. In 2005, Nigeria changed its policy on prevention of malaria in pregnancy to intermittent preventive treatment with sulphadoxine-pyrimethamine (IPTp-SP). Indicators of impact of effective prevention and control of malaria on pregnancy (MIP) are low birth weight (LBW) and maternal anaemia by parity. This study determined the prevalence of LBW for different gravidity groups during periods of pre- and postpolicy change to IPTp-SP. Methods. Eleven-year data were abstracted from the delivery registers of two hospitals. Study outcomes calculated for both pre- (2000–2004) and post-IPTp-SP-policy (2005–2010) years were prevalence of LBW for different gravidity groups and risk of LBW in primigravidae compared to multigravidae. Results. Out of the 11,496 singleton deliveries recorded within the 11-year period, the prevalence of LBW was significantly higher in primigravidae than in multigravidae for both prepolicy (6.3% versus 4%) and postpolicy (8.6% versus 5.1%) years. The risk of LBW in primigravidae compared to multigravidae increased from 1.62 (1.17–2.23) in the prepolicy years to 1.74 (1.436–2.13) during the postpolicy years. Conclusion. The study demonstrated that both the prevalence and risk of LBW remained significantly higher in primigravidae even after the change in policy to IPTp-SP.

scholarly journals Prevalence of Congenital Malaria in Kisangani, A Stable Malaria Transmission Area in Democratic Republic of the Congo

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Labama Otuli Noël ◽  
Bosenge Nguma Jean-Didier ◽  
Maindo Alongo Mike-Antoine ◽  
Katenga Bosunga Gedeon ◽  
Mbo Mukonkole Jean-Paulin ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Malaria Transmission ◽  
Perinatal Mortality ◽  
Intermittent Preventive Treatment ◽  
Preventive Treatment ◽  
Umbilical Blood ◽  
Transmission Area ◽  
Congenital Malaria ◽  
In Pregnancy

Background. Gestational malaria is a major public health problem. It produces fetal complications such as low birth weight, perinatal mortality, and congenital malaria. The present study is aimed at determining the prevalence of congenital malaria and its neonatal complications in the city of Kisangani. Methods. We conducted a cross-sectional study in Kisangani from 1 January to 30 September 2018. Our study population was composed of 1248 newborns born in our study sites, during the period of our study. Just after their birth, we performed the thick drop smear in the placental print and in umbilical blood smear. Results. The prevalence of congenital malaria was 13.98%; 69.23% of newborns who contracted congenital malaria were from 18- to 34-year-old mothers, 53.85% from primiparous mothers, 92.31% from mothers who took intermittent preventive treatment in pregnancy with Sulfadoxine-Pyrimethamine, all (100%) from mothers using the insecticide-treated mosquito nets and 7.69% from HIV-positive mothers. Low birth weight and perinatal mortality were recorded in 76.92% and 7.69% of congenital malaria cases, respectively. Intermittent preventive treatment in pregnancy with Sulfadoxine-Pyrimethamine had no effect on congenital malaria (FE=0.5218; OR: 0.8, 95% CI: 0.1651-3.8769) and on low birth weight (FE=0.3675; OR: 1.2308, 95% CI: 0.0037-0.1464); however, it seemed to have protective effect against perinatal mortality (FE=0.0001; OR: 0.0233, 95% CI: 0.0037-0.1464). Conclusion. Congenital malaria remains a major problem in stable malaria transmission area like Kisangani, and it is grafted by major perinatal complications, particularly low birth weight and perinatal mortality. We recommend an extended study to clarify the relationship between the outcome of pregnancy and the intermittent preventive treatment in pregnancy with Sulfadoxine-Pyrimethamine.

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