Corrigendum to “A Comparison between Piezoelectric Devices and Conventional Rotary Instruments in Bone Harvesting in Patients with Lip and Palate Cleft: A Retrospective Study with Clinical, Radiographical, and Histological Evaluation”

Introduction. Orofacial clefts are congenital malformations characterized by an incomplete shaping of structures that separate the nasal from the oral cavity and can affect the right, left, or both sides. The aim of the present study is to assess, with clinical, radiographical, and histological evaluations, the efficacy of piezoelectric devices compared to traditional rotating instruments in the bone harvesting in patients with history of cleft.Materials and Methods. We have conducted a retrospective analysis on 20 patients with a history of orofacial clefts that were operated on from February 2014 to June 2017. The patients were divided into two groups: Group R in which bone graft was harvested using a burr and Group P in which the bone graft was obtained by a piezoelectric device. After a healing period of 8 months from the grafting procedure, clinical and radiographic evaluations were performed.Results and Discussion. The use of the piezoelectric devices in bone harvesting allows a slight improvement in the final volume. This supports a faster integration into the receiving site.Conclusions.The use of piezoelectric device in patients with history of orofacial cleft that needed bone graft represents a method to be taken into consideration because it has interesting advantages.

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Histological Evaluation of Therapeutic Effect and RCB (Residual Cancer Burden) Index in Primary Breast Cancer Operated after Neoadjuvant Chemotherapy: Retrospective Study of the Clinicopathological Findings and Prognosis

The Showa University Journal of Medical Sciences ◽

10.15369/sujms.29.181 ◽

2017 ◽

Vol 29 (2) ◽

pp. 181-192

Author(s):

Seiya HAJIKANO ◽

Yuko HIROTA ◽

Nobukazu SHIMA ◽

Reika SUZUKI ◽

Terumasa SAWADA ◽

...

Keyword(s):

Breast Cancer ◽

Retrospective Study ◽

Neoadjuvant Chemotherapy ◽

Therapeutic Effect ◽

Primary Breast Cancer ◽

Histological Evaluation ◽

Residual Cancer ◽

Cancer Burden ◽

Residual Cancer Burden ◽

Clinicopathological Findings

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Retrospective Study: Lateral Ridge Augmentation Using Autogenous Dentin: Tooth-Shell Technique vs. Bone-Shell Technique

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18063174 ◽

2021 ◽

Vol 18 (6) ◽

pp. 3174

Author(s):

Michael Korsch ◽

Marco Peichl

Keyword(s):

Retrospective Study ◽

Tissue Loss ◽

Autogenous Bone ◽

Hard Tissue ◽

Ridge Augmentation ◽

Clinical Complications ◽

Bone Harvesting ◽

Lateral Ridge ◽

Bone Substitute Materials ◽

Lateral Ridge Augmentation

In the literature, autogenous dentin is considered a possible alternative to bone substitute materials and autologous bone for certain indications. The aim of this proof-of-concept study was to use autogenous dentin for lateral ridge augmentation. In the present retrospective study, autogenous dentin slices were obtained from teeth and used for the reconstruction of lateral ridge defects (tooth-shell technique (TST): 28 patients (15 females, 13 males) with 34 regions and 38 implants). The bone-shell technique (BST) according to Khoury (31 patients (16 females, 15 males) with 32 regions and 41 implants) on autogenous bone served as the control. Implants were placed simultaneously in both cases. Follow-up was made 3 months after implantation. Target parameters during this period were clinical complications, horizontal hard tissue loss, osseointegration, and integrity of the buccal lamella. The prosthetic restoration with a fixed denture was carried out after 5 months. The total observation period was 5 months. A total of seven complications occurred. Of these, three implants were affected by wound dehiscences (TST: 1, BST: 2) and four by inflammations (TST: 0, BST: 4). There were no significant differences between the two groups in terms of the total number of complications. One implant with TST exhibited a horizontal hard tissue loss of 1 mm and one with BST of 0.5 mm. Other implants were not affected by hard tissue loss. There were no significant differences between the two groups. Integrity of the buccal lamella was preserved in all implants. All implants were completely osseointegrated in TST and BST. All implants could be prosthetically restored with a fixed denture 5 months after augmentation. TST showed results comparable to those of the BST. Dentin can therefore serve as an alternative material to avoid bone harvesting procedures and thus reduce postoperative discomfort of patients.

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Canine papillomatosis: a retrospective study of 24 cases (2001-2011) and immunohistochemical characterization

Pesquisa Veterinária Brasileira ◽

10.1590/s0100-736x2012000700012 ◽

2012 ◽

Vol 32 (7) ◽

pp. 653-657 ◽

Cited By ~ 3

Author(s):

Matheus V. Bianchi ◽

Renata A. Casagrande ◽

Tatiane T.N. Watanabe ◽

Angelica T.B. Wouters ◽

Flademir Wouters ◽

...

Keyword(s):

Retrospective Study ◽

Stratum Corneum ◽

Granular Layer ◽

Histological Evaluation ◽

Cell Nuclei ◽

Viral Particles ◽

Mixed Breed ◽

Positive Immunostaining ◽

Epithelial Lesions ◽

Spinous Layer

A retrospective study of 24 cases of papillomas in dogs was performed from January 2001 to March 2011. Additionally, immunohistochemistry (IHC) was used to characterize and evaluate the samples. We found that disease was observed more in mixed breed dogs, ages ranging from 6 months to 10 years (mean 3.1 years), and there was no gender predilection. The main lesion sites were the skin (75%), lips (16.7%), and eyelids (8.3%). Upon histological evaluation, we observed papillary exophytic proliferation of squamous epithelium and papillary endophytic proliferation (inverted) in 87.5% and 12.5% of cases, respectively. The tumors were characterized by spinous layer hyperplasia (87.5%) with koilocytes (70.8%) and intranuclear pale basophilic inclusions bodies (8.3%), prominent granular layer with large amounts of keratohyalin granules (95.8%), and hyperkeratosis in the stratum corneum (100%). Positive immunostaining for Papillomavirus was found in 83.3% of cases, which were distributed between the granular layer and the stratum corneum. These findings indicate the following: that papillomas in dogs are caused by Papillomavirus, the viral cytopathic effect induces epithelial lesions, viral particles are found inside the cell nuclei, and inclusions bodies are rare.

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Histological evaluation of two different anorganic bovine bone matrixes in lateral wall sinus elevation procedure: A retrospective study

National Journal of Maxillofacial Surgery ◽

10.4103/njms.njms_81_19 ◽

2020 ◽

Vol 11 (2) ◽

pp. 258

Author(s):

MeenuTaneja Bhasin ◽

Lanka Mahesh ◽

Glenn Mascarenhas ◽

Calvo Guirado ◽

Saurabh Juneja

Keyword(s):

Retrospective Study ◽

Lateral Wall ◽

Histological Evaluation ◽

Bovine Bone

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Prognostic Significance of Clinical and Post-Neoadjuvant Chemotherapy Associated Histomorphological Parameters in Osteosarcoma: A Retrospective Study from a Tertiary Care Center

Indian Journal of Medical and Paediatric Oncology ◽

10.1055/s-0041-1740113 ◽

2021 ◽

Author(s):

Navatha Vangala ◽

Shantveer G. Uppin ◽

K. Nageshwara Rao ◽

P. Chandrasekhar ◽

Sadashivudu Gundeti

Keyword(s):

Overall Survival ◽

Retrospective Study ◽

Neoadjuvant Chemotherapy ◽

Tumor Necrosis ◽

Tertiary Care ◽

Prognostic Significance ◽

Prognostic Index ◽

Histological Evaluation ◽

Anatomic Site ◽

Cox Regression Analysis

Abstract Introduction Osteosarcoma is the most prevalent bone cancer in adolescents. Neoadjuvant chemotherapy (NACT) followed by resection is the current modality of treatment for osteosarcoma. Histological evaluation of extent of tumor necrosis on resection is a well-established prognostic indicator in osteosarcoma correlating with survival in most cases. Objectives The main objective of this study was to establish prognostic significance of various clinical and histological parameters post-NACT in osteosarcoma and to compare the integrated prognostic index proposed by Chui et al, with grading of response to NACT by Huvos and Rosen for osteosarcoma. Materials and Methods This is a retrospective study done over a period of four years and includes 47 cases of osteosarcoma treated with NACT. All slides were reviewed and association of various clinical and histological parameters with overall survival was assessed with chi-squared test and Cox-regression analysis. Results Statistical analysis revealed the prognostic significance of age at presentation, anatomic site, primary tumor size, metastatic status, and clinical stage. Histological parameters such as mitosis ≥10/10hpfs, ≥10% residual tumor were significantly associated with poor survival. Tumor necrosis ≥ 90% (excluding areas of hemorrhage, fibrosis and acellular osteoid) was significantly associated with increased survival. An integrated prognostic index formed by combining above parameters gives a better estimate of overall survival compared with residual disease or necrosis alone. Conclusion Integrated prognostic index improves prognostication in patients treated for osteosarcoma.

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Histopathology of human intestinal anastomosis

Eastern Mediterranean Health Journal ◽

10.26719/2003.9.3.413 ◽

2021 ◽

Vol 9 (3) ◽

pp. 413-421 ◽

Cited By ~ 1

Author(s):

M. Shomaf

Keyword(s):

Retrospective Study ◽

Abdominal Surgery ◽

Intestinal Anastomosis ◽

Inflammatory Cells ◽

Histological Evaluation ◽

Histological Changes ◽

Post Surgery ◽

Mucosal Necrosis

The faultless seal of the anastomosis is an important aspect of abdominal surgery but opportunities to make a histological evaluation of human intestinal anastomosis sites are rare. This retrospective study examined 30 anastomoses that had been resected following complications or postmortem; the aim was to describe the histological changes at various stages of healing ranging from 4 days to 3.5 years post-surgery. Anastomosis dehiscence showed features of extensive mucosal necrosis and bad submucosal apposition. Old healed anastomoses continued to have chronic inflammatory cells and muscular discontinuity with areas of intervening fibrosis. It would be useful to underst and more about how the intraluminal contents are propelled through this scarred area

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Histological evaluation of cochlear hair cell damage from noise-induced hearing loss in chinchillas

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100159217 ◽

1990 ◽

Vol 48 (3) ◽

pp. 332-333

Author(s):

R.V. Harrison ◽

R.J. Mount ◽

P. White ◽

N. Fukushima

Keyword(s):

Hair Cell ◽

Evoked Potential ◽

Cell Damage ◽

Acoustic Trauma ◽

Histological Evaluation ◽

Cell Integrity ◽

Functional Changes ◽

Cochlear Hair Cell ◽

Left And Right ◽

Contralateral Ear

In studies which attempt to define the influence of various factors on recovery of hair cell integrity after acoustic trauma, an experimental and a control ear which initially have equal degrees of damage are required. With in a group of animals receiving an identical level of acoustic trauma there is more symmetry between the ears of each individual, in respect to function, than between animals. Figure 1 illustrates this, left and right cochlear evoked potential (CAP) audiograms are shown for two chinchillas receiving identical trauma. For this reason the contralateral ear is used as control.To compliment such functional evaluations we have devised a scoring system, based on the condition of hair cell stereocilia as revealed by scanning electron microscopy, which permits total stereociliar damage to be expressed numerically. This quantification permits correlation of the degree of structural pathology with functional changes. In this paper wereport experiments to verify the symmetry of stereociliar integrity between two ears, both for normal (non-exposed) animals and chinchillas in which each ear has received identical noise trauma.

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