scholarly journals A Case of 14-Year-Old Male with Fibroma of Tendon Sheath of the Hand with Novel Chromosomal Translocation 4;10

2019 ◽  
Vol 2019 ◽  
pp. 1-4 ◽  
Author(s):  
Aaron Rubinstein ◽  
Valerie Fitzhugh ◽  
Irfan Ahmed ◽  
Michael Vosbikian
Keyword(s):  
Soft Tissue Mass ◽  
Case Reports ◽  
Chromosomal Translocation ◽  
Tendon Sheath ◽  
Chromosomal Translocations ◽  
Tissue Mass ◽  
Karyotypic Analysis ◽  
Left Hand ◽  
Slow Growing ◽  
Firm Mass

Fibroma of tendon sheath (FTS) is an uncommonly encountered soft tissue mass, which is morphologically distinct from the more commonly seen giant cell tumor of tendon sheath (GCTTS). Initially described in 1936, FTS is typically a slow growing, painless, firm mass with a predilection for the upper extremity, frequently involving the hand. Cases of associated triggering or compression neuropathies have been described when underlying tendons or nerves are affected. Currently, the literature on FTS is sparse and largely limited to case reports. More recently, few reports of cytogenetic analysis on FTS have been reported in the literature. Cellular and chromosomal analysis of FTS tissue revealed chromosomal translocations with yet unknown clinical significance. Here, we present a case report of FTS in a 14-year-old male with a painless enlarging mass on the palmar side of the left hand treated by excision. Subsequent karyotypic analysis revealed a chromosomal translocation t(4;10) (p16;q24), add (10)(q22)[24]. To our knowledge, this is the first description of this chromosomal aberration in the literature.

scholarly journals Nasopharyngeal nephroblastoma in a 3-month-old Boer goat

2020 ◽  
Vol 33 (1) ◽  
pp. 108-111
Author(s):  
Jillian M. Athey ◽  
Laura E. Rice ◽  
Aja B. Harvey ◽  
Kevin E. Washburn ◽  
Aline Rodrigues-Hoffmann
Keyword(s):  
Wilms Tumor ◽  
Soft Tissue Mass ◽  
Upper Airway ◽  
Nasal Passage ◽  
Cardiorespiratory Arrest ◽  
Tissue Mass ◽  
Boer Goat ◽  
Wilms Tumor 1 ◽  
Glomeruloid Structures ◽  
Firm Mass

A 3-mo-old, female Boer goat was presented because of respiratory difficulties. Tachypnea and inspiratory dyspnea were noted during physical examination. Thoracic radiographs were unremarkable; however, upper airway and nasal passage radiographs revealed a soft tissue mass within the nasal passages. The patient underwent cardiorespiratory arrest and did not respond to resuscitation efforts during endoscopy. A large, pedunculated, semi-firm mass originated from the soft palate and obstructed 90% of the nasopharynx on autopsy. Histologically, the mass was composed of primitive cells that multifocally formed tubules and glomeruloid structures intermingled with areas of fusiform and blastemal cells. The neoplastic cells were positive for cytokeratin (tubular and glomeruloid cells), vimentin (fusiform population and blastemal cells), and Wilms tumor 1 protein (glomeruloid structures) on immunohistochemistry, consistent with a triphasic nephroblastoma. To our knowledge, nasopharyngeal nephroblastoma has not been reported previously in any species.

scholarly journals Intramedullary Chondrosarcoma of Proximal Humerus

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Pratiksha Yadav ◽  
Dolly Thakkar ◽  
S. S. Thind
Keyword(s):  
Proximal Humerus ◽  
Soft Tissue Mass ◽  
Tracer Uptake ◽  
Wide Resection ◽  
Endoprosthetic Reconstruction ◽  
Primary Malignancy ◽  
Tissue Mass ◽  
The Third ◽  
Intramedullary Lesion ◽  
Slow Growing

Primary chondrosarcoma is the third most frequent primary malignancy of bone after myeloma and osteosarcoma. It is ranging from slow growing nonmetastasising lesions to highly aggressive lesions. We report a case of primary intramedullary chondrosarcoma of proximal humerus. A 60-year-old female presented with pain and hard swelling involving the left arm for 5 months. Radiograph showed a lucent expansile intramedullary lesion with matrix calcification and associated soft tissue mass. CT confirmed the finding. MRI showed a lobulated lesion which is hyperintense on T2WI with low signal fibrous septae. Increased tracer uptake was seen on bone scan. Histopathology confirmed the radiology diagnosis. The patient underwent wide resection and endoprosthetic reconstruction of proximal humerus.

Unusual cause of a painless soft tissue mass of the scalp: a rare presentation of primary intracranial neuroendocrine neoplasm

2021 ◽  
Vol 14 (2) ◽  
pp. e236856
Author(s):  
Susruta Manivannan ◽  
Feras Sharouf ◽  
George Lammie ◽  
Paul Leach
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Mass ◽  
Neuroendocrine Tumour ◽  
Clinical Findings ◽  
Neuroendocrine Neoplasm ◽  
Tumour Resection ◽  
Rare Presentation ◽  
Tissue Mass ◽  
Left Hand ◽  
History Of

Incidental soft tissue lumps in the scalp are a common presenting complaint in clinical practice. However, they may signify more sinister underlying pathologies. Our report examines a 63-year-old man presenting with impaired co-ordination in his left hand following a 3-month history of a painless left retroauricular scalp lump. MRI revealed a large left occipital soft tissue mass eroding through the underlying skull with infiltration into the underlying cerebellum and temporal lobe. Open biopsy confirmed a diagnosis of high-grade intracranial neuroendocrine tumour (NET). At approximately 5 months following successful tumour resection and adjuvant chemotherapy, he developed tumour recurrence and was subsequently palliated, and died at 1 year post diagnosis. Herein, we review other cases of primary intracranial NET, clinical findings, histopathological features and prognosis.

scholarly journals Ossifying Fibroma in a Llama

2000 ◽  
Vol 12 (5) ◽  
pp. 473-476 ◽  
Author(s):  
Charles T. McCauley ◽  
Gregory A. Campbell ◽  
Connie A. Cummings ◽  
Wm. Tod Drost
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Mass ◽  
Postmortem Examination ◽  
Ossifying Fibroma ◽  
Nasal Discharge ◽  
Left Nostril ◽  
Medial Canthus ◽  
Tissue Mass ◽  
Second Molar ◽  
Firm Mass

A 4.5-year-old llama was admitted for evaluation of a firm mass rostral and ventral to the medial canthus of the left eye. Mucopurulent nasal discharge and absence of airflow through the left nostril were noted. Radiographs of the skull revealed a sharply demarcated soft tissue mass with faint mineralization. Endoscopy of the nasal passages revealed a mucosa-covered mass originating in the area of the second premolar, extending to the edge of the soft palate, and obstructing the airway. Examination of the oral cavity revealed a missing second molar and a mass protruding 2-cm from the empty alveolus. An ossifying fibroma, a previously unre-ported tumor in llamas, was diagnosed at postmortem examination.

scholarly journals A rare case of a gigantic myxoid liposarcoma of vulva: case report

2021 ◽  
Vol 10 (3) ◽  
pp. 1174
Author(s):  
Tanudeep Kaur ◽  
Ravinder P. Singh
Keyword(s):  
Magnetic Resonance Imaging ◽  
Adjuvant Radiotherapy ◽  
Rare Case ◽  
Soft Tissue Mass ◽  
Case Reports ◽  
Myxoid Liposarcoma ◽  
Resonance Imaging ◽  
Tissue Mass ◽  
Per Se

Vulval malignancies per se are very rare and a liposarcoma in this location is rarer still. The literature consists only of case reports of patients, often with a very limited follow up. We present a rare case of a young 30 year old unmarried nulliparous woman presenting with a giant vulval mass of 30×20 cm and weighing nearly 6 kilograms. Ultrasonography, Computed Tomography, Magnetic Resonance Imaging and biopsy were done. Local resection with adjuvant radiotherapy was given. Histopathology was suggestive of myxoid liposarcoma and the patient is presently recurrence free with over 8 years of follow up. Though rare, myxoid liposarcoma should be kept in differential diagnosis of vulval soft tissue mass. Management includes a combination of surgery and radiation. Excision of lymph nodes is not recommended. Strict prolonged follow up for recurrence or metastasis is mandatory, and any new complaints should be addressed promptly. This is particularly true in the setting of liposarcoma, which may exhibit unusual patterns of spread and recurrence.

GIANT CELL TUMOUR OF TENDON SHEATH IN A CHILD: A CASE REPORT

Hand Surgery ◽  
2005 ◽  
Vol 10 (01) ◽  
pp. 97-100 ◽  
Author(s):  
Narayan Hulse ◽  
Stewart J. Watson
Keyword(s):  
Giant Cell ◽  
Giant Cell Tumour ◽  
Soft Tissue Mass ◽  
Ring Finger ◽  
Surgical Excision ◽  
Tendon Sheath ◽  
Distal Phalanx ◽  
Cell Tumour ◽  
Tissue Mass ◽  
The Right

Giant cell tumour of the tendon sheath is uncommon in children. We describe this tumour arising from the right ring finger in an eight-year-old girl. Plane radiographs showed a soft tissue mass with erosion of the distal phalanx. The tumour was treated by surgical excision with good outcome.

scholarly journals Giant cell tumour of the tendon sheath of the spine: clinical features and imaging findings

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Piaoe Zeng ◽  
Annan Zhang ◽  
Le Song ◽  
Jianfang Liu ◽  
Huishu Yuan ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Giant Cell ◽  
Facet Joint ◽  
Giant Cell Tumour ◽  
Soft Tissue Mass ◽  
Bone Destruction ◽  
Tendon Sheath ◽  
Imaging Findings ◽  
Tissue Mass ◽  
Pet Ct

Abstract Objectives To review the clinical and imaging data of spinal giant cell tumour of the tendon sheath (GCTTS) to improve our understanding of the disease. Methods The imaging findings, clinicopathological features and clinical outcomes of 14 patients with pathologically confirmed spinal GCTTS were analysed retrospectively. Results All 14 patients had a single spinal lesion, including ten cervical vertebra lesions and four thoracic vertebra lesions. CT scan findings: The lesions showed osteolytic bone destruction and were centred on the facet joint, eroding the surrounding bone with a paravertebral soft tissue mass. MRI scan findings: all the lesions manifested predominantly as isointense or hypointense on T1-weighted imaging (T1WI). On T2-weighted imaging (T2WI), eight lesions were hypointense, and four were isointense. The remaining two lesions showed slight hyperintensity. The enhanced scans of eight lesions showed moderate to marked homogeneous or heterogeneous enhancement. PET/CT findings: Among the five patients who underwent PET/CT, three presented lesions with well-defined, sclerotic borders, and the uptake of 18F-FDG was markedly increased. One lesion showed an ill-defined border and an uneven increase in 18F-FDG uptake with an SUVmax value of 8.9. A recurrent lesion was only found on PET/CT 45 months after surgery and the SUVmax was 5.1. Conclusions Spinal GCTTS is extremely rare. Osteolytic bone destruction in the area of the facet joint with a soft tissue mass and hypointensity on T2WI images are indicative of the spinal GCTTS. GCTTS shows high uptake of 18F-FDG, and PET/CT is helpful in detecting recurrent lesions.

Rare Schwannoma Nerve Tumor in a Lesser Toe: A Case Report

2019 ◽  
Vol 109 (4) ◽  
pp. 322-326 ◽  
Author(s):  
Anthony S. Jabra ◽  
Johanna Godoy
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Benign Tumor ◽  
Clinical Presentation ◽  
Soft Tissue Mass ◽  
Case Reports ◽  
Advanced Imaging ◽  
Tissue Mass ◽  
Nerve Tumor ◽  
Rare Location

A schwannoma is a solitary benign tumor composed of Schwann cells occurring anywhere in the peripheral nervous system. The diagnosis of a schwannoma is often difficult to make by clinical presentation and advanced imaging modalities. We present a case report of a 61-year-old Hispanic woman with a left-foot, third-digit, soft-tissue mass. The diagnosis of a schwannoma of the proper digital nerve was made postsurgically by means of histopathologic and immunohistochemistry parameters. This is a rare location for a schwannoma, and neurogenic tumor should be included in the differential diagnosis of soft-tissue mass, as there have been prior case reports.

MULTIPLE LOCALIZED GIANT CELL TUMOR OF THE TENDON SHEATH (GCTTS) AFFECTING A SINGLE TENDON: A VERY RARE CASE REPORT AND REVIEW OF RECENT CASES

Hand Surgery ◽  
2011 ◽  
Vol 16 (03) ◽  
pp. 367-369 ◽  
Author(s):  
Talvinder Singh ◽  
Saqib Noor ◽  
Adrian W. Simons
Keyword(s):  
Soft Tissue ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Rare Case ◽  
Case Reports ◽  
Tendon Sheath ◽  
Cell Tumor ◽  
Giant Cell Tumors ◽  
Mri Scan ◽  
Tissue Mass

Introduction Giant cell tumors of the tendon sheath (GCTTS) are very common. More recently, a small number of case reports have identified the presence of multifocal GCTTS in the hand. These case reports have identified the presence of a maximum of two simultaneous lesions of a giant cell tumor affecting the same tendon sheath. We present an exceptionally rare case of simultaneous multiple localized GCTTS in which five lesions were identified on a single tendon simultaneously. This number of lesions on a single tendon has never been previously reported. Case: A 37-year-old tree surgeon initially complained of pain in the region of the base of the ring and little fingers. A month later, he developed multiple soft tissue swellings at these sites and a soft tissue mass in the center of the palm relating to the left ring finger. A magnetic resonance imaging (MRI) scan suggested multiple GCTTS. These masses were excised completely without MRI evidence of a recurrence. Multiple GCTTS should be a differential diagnosis of multiple soft tissue swellings in the hand with an MRI scan and complete excision being the appropriate imaging and treatment modality respectively.

scholarly journals Giant epidermal cyst of the arm: a rare presentation

2018 ◽  
Vol 11 (1) ◽  
pp. e227615
Author(s):  
Shaan Patel ◽  
Key Yan Tsoi ◽  
George Joseph
Keyword(s):  
Soft Tissue ◽  
Upper Extremity ◽  
Surgical Resection ◽  
Soft Tissue Mass ◽  
Epidermal Cyst ◽  
Lateral Aspect ◽  
Rare Presentation ◽  
Tissue Mass ◽  
Slow Growing

A giant epidermal cyst is a benign soft tissue mass commonly involving the trunk, hand and face. The authors report a rare presentation of a 69-year-old man who presented with a painful, slow-growing left arm mass for 30 years duration. Examination revealed a large, mobile, soft tissue mass of the lateral aspect of the left arm. MRI showed a large, cystic left arm soft tissue mass. The mass was excised and the diagnosis of a giant epidermal cyst was made based on imaging and histopathology after surgical resection. The mass measured 9.5 cm x 8 cm x 4 cm, which is the largest reported giant epidermal cyst of the upper extremity.

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