Giant epidermal cyst of the arm: a rare presentation

A giant epidermal cyst is a benign soft tissue mass commonly involving the trunk, hand and face. The authors report a rare presentation of a 69-year-old man who presented with a painful, slow-growing left arm mass for 30 years duration. Examination revealed a large, mobile, soft tissue mass of the lateral aspect of the left arm. MRI showed a large, cystic left arm soft tissue mass. The mass was excised and the diagnosis of a giant epidermal cyst was made based on imaging and histopathology after surgical resection. The mass measured 9.5 cm x 8 cm x 4 cm, which is the largest reported giant epidermal cyst of the upper extremity.

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Soft Tissue Tumor Leg - A Rare Presentation of Cutaneous Rhinosporidiosis

10.31487/j.jscr.2020.02.08 ◽

2020 ◽

pp. 1-2

Author(s):

R. Chithra ◽

B Sai Dhandapani ◽

R King Gandhi ◽

R. Chithra

Keyword(s):

Soft Tissue ◽

Soft Tissue Tumor ◽

Soft Tissue Mass ◽

Radiological Findings ◽

Rare Presentation ◽

Diagnostic Dilemma ◽

Tissue Mass ◽

Tissue Tumor ◽

Typical History ◽

Polypoidal Growth

Rhinosporidiosis presents commonly as polypoidal growth in nose, but presentation in other sites including skin, genitourinary tract is documented. Cutaneous presentation is rare, which may present as pedunculated swelling or cutaneous ulceration, but presenting as soft tissue tumor is extremely rare. The multifaceted presentation of the disease causes diagnostic dilemma to an unsuspecting physician. Clinical and radiological findings may mislead, but usually typical history helps, and typical histology clinches the diagnosis. We are presenting a case of disseminated cutaneous rhinosporidiosis presented as soft tissue mass lesion in the leg causing diagnostic difficulty due to the rare presentation.

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Unusual cause of a painless soft tissue mass of the scalp: a rare presentation of primary intracranial neuroendocrine neoplasm

BMJ Case Reports ◽

10.1136/bcr-2020-236856 ◽

2021 ◽

Vol 14 (2) ◽

pp. e236856

Author(s):

Susruta Manivannan ◽

Feras Sharouf ◽

George Lammie ◽

Paul Leach

Keyword(s):

Soft Tissue ◽

Soft Tissue Mass ◽

Neuroendocrine Tumour ◽

Clinical Findings ◽

Neuroendocrine Neoplasm ◽

Tumour Resection ◽

Rare Presentation ◽

Tissue Mass ◽

Left Hand ◽

History Of

Incidental soft tissue lumps in the scalp are a common presenting complaint in clinical practice. However, they may signify more sinister underlying pathologies. Our report examines a 63-year-old man presenting with impaired co-ordination in his left hand following a 3-month history of a painless left retroauricular scalp lump. MRI revealed a large left occipital soft tissue mass eroding through the underlying skull with infiltration into the underlying cerebellum and temporal lobe. Open biopsy confirmed a diagnosis of high-grade intracranial neuroendocrine tumour (NET). At approximately 5 months following successful tumour resection and adjuvant chemotherapy, he developed tumour recurrence and was subsequently palliated, and died at 1 year post diagnosis. Herein, we review other cases of primary intracranial NET, clinical findings, histopathological features and prognosis.

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Giant epidermal cyst of the foot

Srpski arhiv za celokupno lekarstvo ◽

10.2298/sarh1410607m ◽

2014 ◽

Vol 142 (9-10) ◽

pp. 607-609 ◽

Cited By ~ 2

Author(s):

Melih Malkoc ◽

Özgür Korkmaz ◽

Yıldıray Genç ◽

Ferhat Say ◽

Mahmut Aytekin

Keyword(s):

Soft Tissue ◽

Epidermoid Cyst ◽

Soft Tissue Mass ◽

Surgical Excision ◽

Epidermal Cyst ◽

Pathology Report ◽

X Rays ◽

Tissue Mass ◽

Palpable Mass ◽

Soft Tissue Masses

Introduction. Epidermoid inclusion cysts are usually composed of epidermal elements implanted into the dermal layers. Patients are seen in the outpatient clinics with a mass. Most of the complaints are mechanical and cosmetic problems. Case Outline. A 34-year-old female patient was admitted to our clinic because of swelling and pain in her right foot. A palpable mass was detected in the first web. On the x-rays of the foot no osseous lesion was detected. There was a soft tissue mass in the first web according to MRI report. Soft tissue mass was excised and sent to pathology. According to pathology report the mass was an epidermoid cyst 5?2?1.5 cm in size. There were no problems during follow-up of the patient for 6 months after surgery. The patient had no swelling in the foot and had no additional complaints on checkup. Conclusion. In the differential diagnosis, we should take into consideration epidermoid cyst of large soft tissue masses of the foot. Surgical excision should be done within the appropriate limits.

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Acute Promyelocytic Leukemia with FLT3/ITD and RUNX1 Mutation Presenting As Extramedullary Soft Tissue Mass

Blood ◽

10.1182/blood.v128.22.5185.5185 ◽

2016 ◽

Vol 128 (22) ◽

pp. 5185-5185

Author(s):

Shahram Mori ◽

Cai Yuan ◽

Wesam B. Ahmed ◽

Rushang D. Patel

Keyword(s):

Bone Marrow ◽

Soft Tissue ◽

Acute Promyelocytic Leukemia ◽

Soft Tissue Mass ◽

Promyelocytic Leukemia ◽

Myeloid Sarcoma ◽

Rare Presentation ◽

Tissue Mass ◽

Significant Information ◽

Runx1 Mutation

Abstract Background: APL formerly known as AML M3 is a variant of myeloid malignancies characterized by recurrent cytogenetic abnormality of PML/RARA translocation, t(15;17). Myeloid sarcoma, also called granulocytic sarcoma or chloroma, is a very rare presentation of extramedullary APL. In rare cases seen, it presents mainly as CNS disease in relapsed or refractory patients. Extramedullary APL on initial presentation is even rarer. As a result no significant information exists on the prognosis of such patients. Case report: A 50-year-old Caucasian female with no past medical history, presented with 6-month duration of chest pain, which was treated as costochondritis without any improvement. Three months later, a soft tissue mass was identified on her sternum. Complete blood count revealed pancytopenia with white blood cell 3.24 x 103/uL, hemoglobin 10.0 g/dL, platelets 58x 103/uL, absolute neutrophil count 1.13 x103/uL, and monocytes 0.13 x103/uL which indicated "low risk disease". A PET/CT scan revealed a 4.6 cm x 4 cm sternal soft tissue mass. The biopsy of the mass confirmed myeloid sarcoma. Bone marrow biopsy showed acute promyelocytic leukemia, approximately 20% blasts in a hypercellular marrow with 70-80% cellularity. Cytogenesis test was negative. FISH analysis subsequently showed a partial RARA transcript inserted at the PML locus suggestive of a cryptic PML/RARA. This was confirmed by PCR for the fusion transcript PML/RARA from the bone marrow. Next generation genome sequencing identified FLT3/ITD and RUNX1 mutation. The patient was treated as a high risk disease due to the presence of chloroma and immediately started on treatment with Daunorubicin, Arsenic Trioxide (ATO), and All-Trans-Retinoic Acid (ATRA). Conclusion: We present an extremely rare case of APL initially presenting with concomitant extramedullary sternal soft tissue mass with cryptic t(15;17) and somatic mutations in FLT/ITD as well as RUNX1 mutations. To our knowledge this is the first reported case of extramedullary APL with FLT/ITD and RUNX1 mutations. Early recognition of this rare presentation with timely chemotherapy may improve the outcomes of these patients. Disclosures No relevant conflicts of interest to declare.

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Pedal Fungal Mass in the Midwest

Journal of the American Podiatric Medical Association ◽

10.7547/17-036 ◽

2018 ◽

Vol 108 (4) ◽

pp. 334-339

Author(s):

Sarah N. Standish ◽

Wendy Goldstein ◽

Chase R. Stuart

Keyword(s):

United States ◽

Soft Tissue ◽

Surgical Resection ◽

Successful Treatment ◽

Soft Tissue Mass ◽

Hepatic Function ◽

The United States ◽

Tissue Mass ◽

Tropical Regions ◽

Rare Finding

Mycetoma cases are predominantly found in tropical regions and are a rare finding in the United States. These masses that are fungal or bacterial in origin can result in significant destruction of soft tissue and bone. We present a case of a patient who emigrated from Mexico to Indianapolis. He presented with a soft-tissue mass that was excised and ultimately found to be a eumycetoma of the hallux of his left foot. Successful treatment included surgical resection in combination with postoperative terbinafine, which was pulse dosed to decrease its impact on hepatic function.

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Canine distal hindlimb soft tissue sarcoma – a novel approach to surgical defect closure

Veterinary and Comparative Orthopaedics and Traumatology ◽

10.3415/vcot-10-05-0072 ◽

2011 ◽

Vol 24 (01) ◽

pp. 84-88 ◽

Cited By ~ 1

Author(s):

D. Heidenreich ◽

Y. Fourie ◽

P. Barreau

Keyword(s):

Soft Tissue ◽

Soft Tissue Sarcoma ◽

Achilles Tendon ◽

Soft Tissue Mass ◽

Postoperative Management ◽

Lateral Aspect ◽

Tissue Mass ◽

Novel Approach ◽

Complete Wound Healing ◽

Exercise Restriction

SummaryA 10-year-old, male, neutered whippet was presented with a soft tissue mass located on the medial aspect of the distal right tibia. The mass was 4 cm in diameter and of two months duration. Recent biopsy by the referring veterinarian, prompted by noticeable enlargement, identified the mass as a soft tissue sarcoma. Staging assessments did not reveal any evidence of metastases. Marginal excision was performed. The resultant defect was closed primarily by the creation of a bipedicle flap on the distal caudo-lateral aspect of the crus to enclose the Achilles tendon separately, leaving a defect between the Achilles tendon and the tibia. Postoperative management entailed support dressings and exercise restriction. Complete wound healing was attained three weeks postoperatively with excellent return of function. No recurrence was noted at eight months post-resection.

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