scholarly journals Intramedullary Chondrosarcoma of Proximal Humerus

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Pratiksha Yadav ◽  
Dolly Thakkar ◽  
S. S. Thind
Keyword(s):  
Proximal Humerus ◽  
Soft Tissue Mass ◽  
Tracer Uptake ◽  
Wide Resection ◽  
Endoprosthetic Reconstruction ◽  
Primary Malignancy ◽  
Tissue Mass ◽  
The Third ◽  
Intramedullary Lesion ◽  
Slow Growing

Primary chondrosarcoma is the third most frequent primary malignancy of bone after myeloma and osteosarcoma. It is ranging from slow growing nonmetastasising lesions to highly aggressive lesions. We report a case of primary intramedullary chondrosarcoma of proximal humerus. A 60-year-old female presented with pain and hard swelling involving the left arm for 5 months. Radiograph showed a lucent expansile intramedullary lesion with matrix calcification and associated soft tissue mass. CT confirmed the finding. MRI showed a lobulated lesion which is hyperintense on T2WI with low signal fibrous septae. Increased tracer uptake was seen on bone scan. Histopathology confirmed the radiology diagnosis. The patient underwent wide resection and endoprosthetic reconstruction of proximal humerus.

scholarly journals A Case of 14-Year-Old Male with Fibroma of Tendon Sheath of the Hand with Novel Chromosomal Translocation 4;10

2019 ◽  
Vol 2019 ◽  
pp. 1-4 ◽  
Author(s):  
Aaron Rubinstein ◽  
Valerie Fitzhugh ◽  
Irfan Ahmed ◽  
Michael Vosbikian
Keyword(s):  
Soft Tissue Mass ◽  
Case Reports ◽  
Chromosomal Translocation ◽  
Tendon Sheath ◽  
Chromosomal Translocations ◽  
Tissue Mass ◽  
Karyotypic Analysis ◽  
Left Hand ◽  
Slow Growing ◽  
Firm Mass

Fibroma of tendon sheath (FTS) is an uncommonly encountered soft tissue mass, which is morphologically distinct from the more commonly seen giant cell tumor of tendon sheath (GCTTS). Initially described in 1936, FTS is typically a slow growing, painless, firm mass with a predilection for the upper extremity, frequently involving the hand. Cases of associated triggering or compression neuropathies have been described when underlying tendons or nerves are affected. Currently, the literature on FTS is sparse and largely limited to case reports. More recently, few reports of cytogenetic analysis on FTS have been reported in the literature. Cellular and chromosomal analysis of FTS tissue revealed chromosomal translocations with yet unknown clinical significance. Here, we present a case report of FTS in a 14-year-old male with a painless enlarging mass on the palmar side of the left hand treated by excision. Subsequent karyotypic analysis revealed a chromosomal translocation t(4;10) (p16;q24), add (10)(q22)[24]. To our knowledge, this is the first description of this chromosomal aberration in the literature.

Multifocal lymphangioendotheliomatosis with devastating intracranial hemorrhage

2013 ◽  
Vol 12 (5) ◽  
pp. 517-520 ◽  
Author(s):  
Christina Huang ◽  
Elias Rizk ◽  
Mark Iantosca ◽  
Andrea L. Zaenglein ◽  
Klaus F. Helm ◽  
...  
Keyword(s):  
Intracranial Hemorrhage ◽  
Developmental Delays ◽  
Soft Tissue Mass ◽  
Skin Lesions ◽  
In Utero ◽  
Vascular Disorder ◽  
Intracranial Hemorrhages ◽  
Tissue Mass ◽  
Foramen Of Monro ◽  
The Third

An in utero female was found to have a small hemorrhage at the foramen of Monro, hydrocephalus, and what was originally interpreted as a Dandy-Walker variant. At birth she had macrocephaly and numerous cutaneous, multifocal, red-pink blanchable macules. Postnatal MRI demonstrated a hemorrhagic soft-tissue mass involving the upper brainstem, thalamus, and basal ganglia most consistent with in utero complex multifocal intracranial hemorrhage. The skin lesions were thought to be consistent with multifocal lymphangioendotheliomatosis with thrombocytopenia (MLT). The size and location of the hemorrhage precluded operative intervention, although the hydrocephalus was treated with a ventricular shunt. The child continues to have severe developmental delays. Multifocal lymphangioendotheliomatosis with thrombocytopenia is a multifocal vascular disorder most commonly involving the skin and gastrointestinal tract. Intracranial hemorrhages are rare in this context. This case is the third reported instance of MLT with associated intracranial hemorrhage and the only case described in the neurosurgical literature. The authors review the presenting features and pathophysiology of this condition.

scholarly journals Aggressive Angiomyxoma with Perineal Herniation

2014 ◽  
Vol 4 ◽  
pp. 23 ◽  
Author(s):  
Seema Narang ◽  
Supreethi Kohli ◽  
Vinod Kumar ◽  
Raj Chandoke
Keyword(s):  
Surgical Planning ◽  
Soft Tissue Mass ◽  
Aggressive Angiomyxoma ◽  
Radiological Evaluation ◽  
Perianal Region ◽  
Tissue Mass ◽  
The Third ◽  
Fourth Decade ◽  
Perineal Herniation ◽  
Perineal Region

Aggressive angiomyxoma is a rare mesenchymal tumor involving the pelvic-perineal region. It occurs during the third and fourth decade of life and is predominantly seen in females. It presents clinically as a soft tissue mass in variable locations such as vulva, perianal region, buttock, or pelvis. Assessment of extent of the tumor by radiological evaluation is crucial for surgical planning; however, biopsy is essential to establish diagnosis. We present the radiological and pathological features seen in a 43-year-old female diagnosed with abdominal angiomyxoma with an unusual extension to the perineum.

Osteoblastoma of the Foot and Ankle

1998 ◽  
Vol 19 (10) ◽  
pp. 698-704 ◽  
Author(s):  
H. Thomas Temple ◽  
Mark S. Mizel ◽  
Mark D. Murphey ◽  
Donald E. Sweet
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Mass ◽  
Armed Forces ◽  
Foot And Ankle ◽  
Common Site ◽  
Tissue Mass ◽  
Male Predominance ◽  
The Third ◽  
History Of ◽  
The Mean

A total of 329 patients with osteoblastoma were retrospectively reviewed from the archives of the Armed Forces Institute of Pathology, of which 41 (12.5%) presented with tumors in the foot and ankle. This was the third most common site of disease after the spine and femur. Overall, the mean age was 22.5 years, which was the same for the foot and ankle subset of patients; however, there was a significant male predominance in foot and ankle patients compared with the whole group. The majority of patients were skeletally mature (85.4%). Clinically, most patients presented with pain (97.2%), although one-third of the total related a history of antecedent trauma. The interval between the onset of symptoms and biopsy was 84 days (range, 0–572 days). Radiographically, the majority of lesions were in the hindfoot (N = 18; 44%) of which 16 of 18 tumors (89%) were in the talus. Of these, one-half were subperiosteal and dorsally based and were associated with osseous tumor matrix and a soft tissue mass. Two osteoblastomas, both in the metatarsals, transitioned into sarcomas; the rest were histologically benign. For diagnostic purposes, it was essential to obtain clinical, radiographic, and histologic correlation.

scholarly journals Giant epidermal cyst of the arm: a rare presentation

2018 ◽  
Vol 11 (1) ◽  
pp. e227615
Author(s):  
Shaan Patel ◽  
Key Yan Tsoi ◽  
George Joseph
Keyword(s):  
Soft Tissue ◽  
Upper Extremity ◽  
Surgical Resection ◽  
Soft Tissue Mass ◽  
Epidermal Cyst ◽  
Lateral Aspect ◽  
Rare Presentation ◽  
Tissue Mass ◽  
Slow Growing

A giant epidermal cyst is a benign soft tissue mass commonly involving the trunk, hand and face. The authors report a rare presentation of a 69-year-old man who presented with a painful, slow-growing left arm mass for 30 years duration. Examination revealed a large, mobile, soft tissue mass of the lateral aspect of the left arm. MRI showed a large, cystic left arm soft tissue mass. The mass was excised and the diagnosis of a giant epidermal cyst was made based on imaging and histopathology after surgical resection. The mass measured 9.5 cm x 8 cm x 4 cm, which is the largest reported giant epidermal cyst of the upper extremity.

Floor of mouth schwannoma mimicking a salivary gland neoplasm: a report of the case and review of the literature

2021 ◽  
Vol 14 (2) ◽  
pp. e239452
Author(s):  
Yalda Nassehi ◽  
Arif Rashid ◽  
Gayani Pitiyage ◽  
Rahul Jayaram
Keyword(s):  
Oral Cavity ◽  
Soft Tissue Mass ◽  
Surgical Excision ◽  
Salivary Gland Neoplasm ◽  
Review Of The Literature ◽  
Mri Scan ◽  
Tissue Mass ◽  
Floor Of Mouth ◽  
History Of ◽  
Slow Growing

Schwannomas or neurilemmomas are slow-growing, benign and often firm lumps that are typically painless. They are extremely rare in the oral cavity, with the tongue and the palate being the most common intraoral sites. This is a case report of this pathology in the floor of the mouth. We present a case of a 28-year-old female patient with a 2-month history of a floor of mouth swelling. On clinical examination this was non-tender and appeared firm. An ultrasound of the lesion was performed which revealed a well-defined, rounded and low reflective soft tissue mass. Following an MRI scan and surgical excision of the lesion, a definitive diagnosis of a schwannoma was made. The presence of schwannoma in the oral cavity is unusual. Based on the literature and the presented case, it should be considered as a differential diagnosis until the final histopathological confirmation.

Investigations on skeletal growth zones via bone scans as base of determination of optimal time for surgery in mandibular asymmetry

2000 ◽  
Vol 39 (05) ◽  
pp. 121-126 ◽  
Author(s):  
R. Werz ◽  
P. Reuland
Keyword(s):  
Bone Growth ◽  
Region Of Interest ◽  
Tracer Uptake ◽  
Optimal Time ◽  
Mandibular Bone ◽  
The Third ◽  
Mandibular Asymmetry ◽  
Bone Scans ◽  
Epiphyseal Plates

Summary Aim of the study was to find out wether there is a common stop of growth of mandibular bone, so that no individual determination of the optimal time for surgery in patients with asymmetric mandibular bone growth is needed. As there are no epiphyseal plates in the mandibular bone, stop of growth cannot be determined on X-ray films. Methods: Bone scans of 731 patients [687 patients (324 male, 363 female) under 39 y for exact determination of end of growth and 44 (21 male, 23 female) patients over 40 y for evaluation of nongrowth dependant differences in tracer uptake] were reviewed for the study. All the patients were examined 3 hours after injection of 99mTc-DPD. Tracer uptake was measured by region of interest technique in different points of the mandibular bone and in several epiphyseal plates of extremities. Results: Tracer uptake in different epiphyseal plates of the extremities shows strong variation with age and good correlation with reported data of bone growth and closure of the epiphyseal plates. The relative maximum of bone activity is smaller in mandibular bone than in epiphyseal plates, which show well defined peaks, ending at 15-18 years in females and at 18-21 years in males. In contrast, mandibular bone shows no well defined end of growing but a gradually reduction of bone activity which remains higher than bone activity in epiphyseal plates over several years. Conclusion: No well defined end of growth of mandibular bone exists. The optimal age for surgery of asymmetric mandibular bone growth is not before the middle of the third decade of life, bone scans performed earlier for determination of bone growth can be omitted. Bone scans performed at the middle of the third decade of life help to optimize the time of surgical intervention.

scholarly journals Thymoma in an aged backyard Leghorn chicken, with reviews of a database and literature

2021 ◽  
Vol 33 (2) ◽  
pp. 336-339
Author(s):  
Julia Blakey ◽  
Carmen Jerry ◽  
Ana da Silva ◽  
Simone Stoute
Keyword(s):  
Soft Tissue Mass ◽  
Animal Health ◽  
Postmortem Examination ◽  
Cervical Region ◽  
Laboratory System ◽  
Unexpected Death ◽  
Tissue Mass ◽  
Microscopic Features ◽  
History Of ◽  
Backyard Chickens

A 7-y-old backyard Leghorn chicken ( Gallus domesticus) was submitted to the California Animal Health and Food Safety Laboratory System (CAHFS)–Turlock branch for postmortem examination, with a history of unexpected death. At postmortem examination, a hemorrhagic soft tissue mass was observed in the cervical region. Microscopically, a densely cellular neoplasm of polygonal epithelial cells and small lymphocytes was observed. The microscopic features of the neoplasm in combination with positive immunohistochemistry for pancytokeratin and CD3 were used to classify the lesion as a thymoma. Thymoma was diagnosed in only 5 birds submitted to CAHFS from 1990 to 2019. Thymoma has been described only rarely in birds, and is an unusual diagnosis in backyard chickens.

scholarly journals Extradural Peripheral Nerve Sheath Tumour at T7 Level in a 2-Year-Old Dog

VCOT Open ◽  
2021 ◽  
Vol 04 (01) ◽  
pp. e41-e46
Author(s):  
Federica Aragosa ◽  
Chiara Caterino ◽  
Giovanni Della Valle ◽  
Ilaria D'Aquino ◽  
Dario Costanza ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Soft Tissue Mass ◽  
Resonance Imaging ◽  
Tissue Mass ◽  
Nerve Sheath Tumour ◽  
Free Interval ◽  
Nerve Sheath ◽  
Dorsal Laminectomy ◽  
Intervertebral Foramina ◽  
Peripheral Nerve Sheath Tumour

AbstractThe aim of this report is to describe an unusual localization of nerve sheath tumour (NST), clinical presentation, imaging, surgical management, and outcome in a 2-year-old dog. A 2-year-old female American Staffordshire Terrier presented with nonambulatory paraparesis, thoracolumbar hyperaesthesia, hindlimb hyperreflexia, and mild muscle atrophy. Computed tomography and magnetic resonance imaging revealed an extradural mass at T7-T8, without vertebral lesions. Surgical treatment consisted in resection of the soft tissue mass through dorsal laminectomy. The dog was ambulatory within 24 hours and free of recurrence at 18 months postoperatively. Histopathologic and features of immunohistochemistry were consistent with NST. The NST of this report was similar to those described before, but exhibited unusual characteristics, such as being extradural, without extension into intervertebral foramina, and being located in an atypical region (T7-T8). Moreover, survival time and relapse-free interval are greater than previously reported for similar cases.

Primary renal synovial sarcoma presenting with a retroperitoneal bleed

2021 ◽  
Vol 14 (3) ◽  
pp. e237099
Author(s):  
Daanesh Huned ◽  
Juinn Huar Kam ◽  
Lui Shiong Lee ◽  
Raj Vikesh Tiwari
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Synovial Sarcoma ◽  
Soft Tissue Mass ◽  
Renal Angiomyolipoma ◽  
Right Hepatectomy ◽  
Tissue Mass ◽  
Biopsy Confirmation ◽  
Synovial Sarcomas ◽  
Neo Adjuvant Chemotherapy

Synovial sarcomas are most commonly localised in extremities, especially in the lower thigh and knee areas. Comprising less than 1% of all malignancies, retroperitoneal synovial sarcoma is very rare with primary synovial sarcoma of the kidney being even more infrequent and difficult to diagnose. We describe a case report of a renal synovial sarcoma in a young adult who was initially managed as a case of Wunderlich’s syndrome secondary to what was believed to be a ruptured renal angiomyolipoma. After biopsy confirmation, the patient was eventually managed with neo-adjuvant chemotherapy followed by a right radical nephrectomy and right hepatectomy. Despite its rarity, synovial sarcoma should be considered as differential diagnosis of a bleeding retroperitoneal soft tissue mass detected in young adults.

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