scholarly journals Contrast-Enhanced MRI Texture Parameters as Potential Prognostic Factors for Primary Central Nervous System Lymphoma Patients Receiving High-Dose Methotrexate-Based Chemotherapy

2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Chaoyue Chen ◽  
Hongyu Zhuo ◽  
Xiawei Wei ◽  
Xuelei Ma
Keyword(s):  
Magnetic Resonance Imaging ◽  
Cox Regression ◽  
Central Nervous System Lymphoma ◽  
Texture Features ◽  
Regression Analyses ◽  
Grey Level ◽  
Resonance Imaging ◽  
Contrast Enhanced ◽  
Magnetic Resonance Imaging Mri ◽  
Occurrence Matrix

Introduction. The purpose of this study was to evaluate the prognostic value of texture features on contrast-enhanced magnetic resonance imaging (MRI) for patients with primary central nervous system lymphoma (PCNSL). Methods. In this retrospective study, fifty-two patients diagnosed with PCNSL were enrolled from October 2010 to March 2017. The texture feature of tumor tissue on the histogram-based matrix (histo-) and the grey-level co-occurrence matrix (GLCM) was retrieved by contrast-enhanced T1-weighted imaging before any antitumor treatment. Receiver operating characteristic curve analyses were performed to obtain their optimal cutoff values, based on which we dichotomized patients into subgroups. The Kaplan–Meier analyses were conducted to compare overall survival (OS) of subgroups, and multivariate Cox regression analyses were used to determine if they could be taken as independent prognostic factors. Results. Ten texture features were extracted from the MR image, including Energy, Entropy, Kurtosis, Skewness on the histogram-based matrix, and Correlation, Contrast, Dissimilarity, Energy, Entropy, and Homogeneity on the grey-level co-occurrence matrix. Three of them (GLCM-Contrast, GLCM-Dissimilarity, and GLCM-Homogeneity) are shown to be significant in relation to overall survival (OS). The multivariate Cox regression analyses suggest that GLCM-Homogeneity could be taken as independent predictors. Conclusions. The texture features of contrast-enhanced magnetic resonance imaging (MRI) could potentially serve as prognostic biomarkers for PCNSL patients.

scholarly journals The value of contrast-enhanced FLAIR magnetic resonance imaging in detecting meningeal abnormalities in suspected cases of meningitis compared to conventional contrast-enhanced T1WI sequences

2020 ◽  
Vol 51 (1) ◽  
Author(s):  
Wael Hamza Kamr ◽  
Mohamed Gaber Eissawy ◽  
Amr Saadawy
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Early Diagnosis ◽  
Diagnosis And Treatment ◽  
Effective Management ◽  
Resonance Imaging ◽  
Flair Sequence ◽  
Csf Analysis ◽  
Contrast Enhanced ◽  
Magnetic Resonance Imaging Mri

Abstract Background Early diagnosis of meningitis with magnetic resonance imaging (MRI) would be useful for appropriate and effective management, decrease morbidity and mortality, and provide better diagnosis and treatment. The objective of the current study is to compare the accuracy of contrast-enhanced FLAIR (CE-FLAIR) and contrast-enhanced T1WI (CE-T1WI) in the detection of meningeal abnormalities in suspected cases of meningitis. Results Out of 45 patients, 37 patients were confirmed to have meningitis on CSF analysis. Out of the 37 patients, 34 patients were positive on CE-FLAIR sequence and 27 were positive on CE-T1WI. The sensitivity of CE-FLAIR sequence was 91.9% and specificity 100%, while the sensitivity of CE-T1WI sequence was 73% and specificity 100%. Conclusion CE-FLAIR is more sensitive than CE-T1WI in diagnosis of meningitis. It is recommended to be used in any cases with clinically suspected meningitis.

Magnetic Resonance Imaging in Gynecological Oncology

2009 ◽  
Vol 19 (2) ◽  
pp. 186-193 ◽  
Author(s):  
Vanessa N. Harry ◽  
Heather Deans ◽  
Emma Ramage ◽  
David E. Parkin ◽  
Fiona J. Gilbert
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Resonance Imaging ◽  
Early Assessment ◽  
Contrast Enhanced ◽  
Crucial Information ◽  
Magnetic Resonance Imaging Mri ◽  
Indispensable Tool ◽  
Improving Patient Care

Magnetic resonance imaging (MRI) has become an indispensable tool in the assessment of malignant disease. With increasingly sophisticated systems and technical advancements, MRI has continued to expand its role in providing crucial information regarding cancer diagnosis and management. In gynecological malignancies, this modality has assumed greater responsibility, particularly in the evaluation of cervical and endometrial cancers. In addition to conventional imaging, innovative techniques such as dynamic contrast-enhanced MRI and diffusion-weighted MRI show promise in offering early assessment of tumor response. This paper reviews the current role of MRI in gynecological cancers and highlights the potential of novel techniques in improving patient care.

Endolymphatic Hydrops, Evaluated Using 3T MRI in Patients with Clinically Confirmed Meniere Disease

2019 ◽  
Vol 8 (3) ◽  
pp. 1-5
Author(s):  
Agnieszka Jasińska ◽  
Emilia Wnuk ◽  
Katarzyna Pierchała ◽  
Kazimierz Niemczyk
Keyword(s):  
Magnetic Resonance Imaging ◽  
Endolymphatic Hydrops ◽  
Clinical Development ◽  
Resonance Imaging ◽  
Vestibular Neurectomy ◽  
3T Mri ◽  
Gadolinium Administration ◽  
Contrast Enhanced ◽  
Grading Scale ◽  
Magnetic Resonance Imaging Mri

Ménière’s disease (MD) is characterized by intermittent episodes of vertigo with fluctuating sensorineural hearing loss, tinnitus, and aural fullness. Despite numerous studies, the etiology of this disorder remains poorly understood and thus diagnostic criteria are mainly clinical. Development and progress in magnetic resonance imaging (MRI) techniques, in 2007, has enabled visualization of endolymphatic hydrops, which was the milestone achievement. We present two cases of patients with clinically confirmed MD with a set of audiological, otoneurological examinations and MRI performed. Structures of the inner ear were visualized using contrast-enhanced MR imaging after a 4-hour delayed intravenous gadolinium administration. The cochlea and vestibule were evaluated separately and classified using Barath grading scale. Endolymphatic hydrops in the clinically affected ears was confirmed using MRI. Due to disabling and intractable MD, a decision about vestibular neurectomy was made.

scholarly journals Extramedullary Myxopapillary Ependymoma of the Filum Terminale Associated With Syringomyelia: A Case Report

2013 ◽  
Vol 20 (4) ◽  
pp. 395-398
Author(s):  
Yavuz Samanci ◽  
Suat Erol Celik
Keyword(s):  
Magnetic Resonance Imaging ◽  
Myxopapillary Ependymoma ◽  
Filum Terminale ◽  
Resonance Imaging ◽  
Spinal Lesions ◽  
First Case ◽  
Contrast Enhanced ◽  
Leg Weakness ◽  
Additional Procedure ◽  
Magnetic Resonance Imaging Mri

Abstract Aim: Ependymomas compose the majority of all intradural intramedullary spinal lesions. Filum terminale lesions are rarely associated with syringomyelia. Here we describe a case of extramedullary myxopapillary ependymoma associated with extensive syringomyelia located in the filum terminale. Material and Methods: A 34-year-old man admitted to our clinic with complaints of bilateral leg weakness, back pain and urinary dysfunction. The magnetic resonance imaging (MRI) of the patient showed us a contrast enhanced intraspinal mass at the level of L2 with a syringomyelia extending from L2 level to Th7 level. Results: The patient was operated via lumbar laminoplasty and tumor was totally resected. Conclusion: The removal of tumor is also sufficient for the resolution of syringomyelia and no additional procedure is essential for the treatment of syringomyelia in such cases. This is the first case of extramedullary tumors of the cauda equine with extensive syringomyelia.

scholarly journals Multifocality and Multicentrality in Breast Cancer: Comparison of the Efficiency of Mammography, Contrast-Enhanced Spectral Mammography, and Magnetic Resonance Imaging in a Group of Patients with Primarily Operable Breast Cancer

2021 ◽  
Vol 28 (5) ◽  
pp. 4016-4030
Author(s):  
Katarzyna Steinhof-Radwańska ◽  
Andrzej Lorek ◽  
Michał Holecki ◽  
Anna Barczyk-Gutkowska ◽  
Anna Grażyńska ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Surgical Intervention ◽  
Histopathological Examination ◽  
Breast Conserving Therapy ◽  
Resonance Imaging ◽  
Contrast Enhanced ◽  
Highly Sensitive ◽  
Magnetic Resonance Imaging Mri

Background: The multifocality and multicentrality of breast cancer (MFMCC) are the significant aspects that determine a specialist’s choice between applying breast-conserving therapy (BCT) or performing a mastectomy. This study aimed to assess the usefulness of mammography (MG), contrast-enhanced spectral mammography (CESM), and magnetic resonance imaging (MRI) in women diagnosed with breast cancer before qualifying for surgical intervention to visualize other (additional) cancer foci. Methods: The study included 60 breast cancer cases out of 630 patients initially who underwent surgery due to breast cancer from January 2015 to April 2019. MG, CESM, and MRI were compared with each other in terms of the presence of MFMCC and assessed for compliance with the postoperative histopathological examination (HP). Results: Histopathological examination confirmed the presence of MFMCC in 33/60 (55%) patients. The sensitivity of MG in detecting MFMCC was 50%, and its specificity was 95.83%. For CESM, the sensitivity was 85.29%, and the specificity was 96.15%. For MRI, all the above-mentioned parameters were higher as follows: sensitivity—91.18%; specificity—92.31%. Conclusions: In patients with MFMCC, both CESM and MRI are highly sensitive in the detection of additional cancer foci. Both CESM and MRI change the extent of surgical intervention in every fourth patient.

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