scholarly journals Analysis of Peripapillary and Macular Choroidal Thickness in Eyes with Pseudoexfoliative Glaucoma and Fellow Eyes

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Fan Li ◽  
Qingli Shang ◽  
Guangxian Tang ◽  
Hengli Zhang ◽  
Xiaowei Yan ◽  
...  
Keyword(s):  
Choroidal Thickness ◽  
Enhanced Depth Imaging ◽  
Average Volume ◽  
Depth Imaging ◽  
Pseudoexfoliative Glaucoma ◽  
Group A ◽  
Imaging Optical Coherence Tomography ◽  
Group B ◽  
Control Study ◽  
Fellow Eyes

Purpose. To compare differences in peripapillary and macular choroidal thickness in pseudoexfoliative glaucoma (PXG) eyes, nonexfoliative fellow eyes, and normal eyes. Methods. This case-control study included 37 PXG patients (group A: 37 PXG eyes; group B: 37 nonexfoliative fellow eyes) and 37 sex-, age-, and axial length-matched healthy volunteer eyes (group C). Peripapillary and macular choroidal thickness and volume were measured in all subjects via enhanced-depth imaging-optical coherence tomography. Results. The average peripapillary (AP) choroidal thickness was (130.10 ± 46.14) μm, (131.43 ± 46.00) μm, and (147.89 ± 53.32) μm; average macular (AM) choroidal thickness was (191.72 ± 68.07) μm, (204.62 ± 69.54) μm, and (215.10 ± 45.40) μm; and average volume was (0.59 ± 0.21) μm3, (0.63 ± 0.21) μm3, and (0.65 ± 0.14) μm3 in groups A, B, and C, respectively. NIP choroidal thickness was significantly lower in groups A and B than in group C (P<0.05). TIM and TOM choroidal thickness and volume were significantly lower in group A than in group C (P<0.05). NIM, SIM, NOM, IOM, AM choroidal thickness and volume, and CSM choroidal thickness were significantly lower in group A than in group B (P<0.05). CSM, TIM, and TOM in group A and TIM, TOM choroidal thickness, and volume in group B were significantly lower than in group C (P<0.05). Conclusions. NIP choroidal thickness in PXG eyes and nonexfoliative fellow eyes and temporal macular choroidal thickness in PXG eyes were significantly lower than in normal eyes. Macular choroidal thickness (except in temporal regions) was significantly lower in PXG eyes than in nonexfoliative fellow eyes. Changes in peripapillary and macula choroidal thickness further elucidate the choroid’s role in PXG development and progression.

scholarly journals Comparison of Macular Choroidal Thickness and Volume between Pseudoexfoliative Glaucoma and Pseudoexfoliative Syndrome

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Fan Li ◽  
Lihua Ma ◽  
Yulei Geng ◽  
Xiaowei Yan ◽  
Hengli Zhang ◽  
...  
Keyword(s):  
Choroidal Thickness ◽  
Normal Subjects ◽  
Enhanced Depth Imaging ◽  
Depth Imaging ◽  
Pseudoexfoliative Glaucoma ◽  
Group A ◽  
Imaging Optical Coherence Tomography ◽  
The Difference ◽  
Group B

Purpose. To evaluate the difference in macular choroidal thickness and volume between patients with pseudoexfoliative glaucoma (PXG), patients with pseudoexfoliative syndrome (PEX), and normal controls. Methods. This case-control study included 49 PXG patients (group A), 33 PEX patients (group B), and 42 sex-, age-, and axial length-matched healthy volunteer eyes (group C). The macular choroidal thickness and volume of all subjects studied were measured by enhanced depth imaging optical coherence tomography. Results. The average macular (AM) choroidal thickness was 170.79 ± 50.18 μm, 184.65 ± 57.54 μm, and 206.46 ± 48.90 μm, and the average volume was 0.52 ± 0.15 μm3, 0.56 ± 0.17 μm3, and 0.63 ± 0.15 μm3 in groups A, B, and C, respectively. The macular choroidal thickness, the volumes of various macular regions, and the average choroidal thickness and volume in group A were lower than those in group C (all P < 0.05 ). There were no significant differences in the macular choroidal thickness, volumes of various macular regions, or average choroidal thickness or volume between group A and B (all P > 0.05 ). The macular choroidal thickness and volume of the TIM and SOM in group B were lower than those in group C ( P < 0.05 ). There was no association between the macular choroidal thickness of various macular regions and visual field mean defect (MD) in group A (all P > 0.05 ). Conclusion. The macular choroidal thickness in patients with PXG or PEX (TIM and SOM) is thinner than that in normal subjects. The macular choroidal thickness in patients with PXG is not significantly different from that in patients with PEX. The role of macular choroidal thickness changes in the glaucomatous damage of patients with PXG is still unclear.

scholarly journals Choroidal thickness in eyes with different degrees of myopia

2013 ◽  
Vol 6 (4) ◽  
pp. 34-38 ◽  
Author(s):  
Yuriy Sergeyevich Astakhov ◽  
Svetlana Georgiyevna Belekhova
Keyword(s):  
Optical Coherence Tomography ◽  
Negative Correlation ◽  
Choroidal Thickness ◽  
Healthy People ◽  
Enhanced Depth Imaging ◽  
Control Group ◽  
Depth Imaging ◽  
Subfoveal Choroidal Thickness ◽  
Imaging Optical Coherence Tomography ◽  
Spectralis Oct

66 healthy people (124 eyes) with different degrees of myopia and emmetropia were examined using enhanced depth imaging optical coherence tomography (EDI-OCT) using the “Spectralis OCT”. It was found that the choroid in subjects with medium and high degrees of myopia was significantly thinner than that in the control group. In the study, a negative correlation was found between the subfoveal choroidal thickness and the degree of myopia (r = -0.75, p < 0.0001). It was also found that the subfoveal choroidal thickness decreased for each diopter of myopia by approximately 18.03 μm.

Choroidal thickness evaluation in paediatric patients with adenotonsillar hypertrophy

2017 ◽  
Vol 131 (9) ◽  
pp. 768-772
Author(s):  
A Yenigun ◽  
A Elbay ◽  
A M Hafiz ◽  
O Ozturan
Keyword(s):  
Choroidal Thickness ◽  
Enhanced Depth Imaging ◽  
Control Group ◽  
Healthy Children ◽  
Depth Imaging ◽  
Adenotonsillar Hypertrophy ◽  
Paediatric Patients ◽  
Healthy Control ◽  
Imaging Optical Coherence Tomography ◽  
Thickness Measurements

AbstractObjective:To investigate choroidal thickness using enhanced-depth imaging optical coherence tomography in paediatric patients with adenotonsillar hypertrophy, with comparison to healthy children, three months after adenotonsillectomy.Methods:The patients were assigned to three groups: an adenotonsillar hypertrophy group, an adenotonsillectomy group and a healthy control group. In all groups, subfoveal, temporal and nasal choroidal thickness measurements were taken.Results:In the subfoveal, temporal and nasal regions, choroidal tissue was found to be significantly thinner in adenotonsillar hypertrophy children than healthy children (p = 0.012, p = 0.027 and p = 0.020). The subfoveal and temporal choroidal thickness measurements of adenotonsillar hypertrophy group cases were significantly decreased compared to those in the adenotonsillectomy group (p = 0.038 and p = 0.048).Conclusion:There was a significant association between decreased choroidal thickness and adenotonsillar hypertrophy. Adenotonsillar hypertrophy may play an important role in decreased choroidal thickness.

scholarly journals A Meta-Analysis of Choroidal Thickness Changes in Unilateral Amblyopia

2017 ◽  
Vol 2017 ◽  
pp. 1-10 ◽  
Author(s):  
Yanli Liu ◽  
Yi Dong ◽  
Kanxing Zhao
Keyword(s):  
Choroidal Thickness ◽  
Primary Outcome ◽  
Weighted Mean Difference ◽  
Meta Analysis ◽  
Enhanced Depth Imaging ◽  
Weighted Mean ◽  
Cross Sectional ◽  
Depth Imaging ◽  
Imaging Optical Coherence Tomography ◽  
And Control

Purpose. To date, the topic of amblyopic changes remains controversial. Therefore, a systematic review and meta-analysis were carried out to evaluate choroidal changes in unilateral amblyopia. Methods. Major literature databases were searched for amblyopia-relevant studies. Using enhanced depth imaging optical coherence tomography (EDI-OCT), the primary outcome parameters examined were subfoveal choroidal thickness (SFCT) and different choroidal thickness (CT) positions. Efficacy estimates were evaluated by weighted mean difference (WMD) and 95% confidence interval (CI) for choroidal-associated changes. We performed subgroup analysis and metaregression analysis to examine potential sources of heterogeneity. Results. Eleven cross-sectional studies that included a total of 768 participants were identified. The amblyopic eye SFCT was thicker than that of the fellow and control (normal) eyes (WMDamblyopia versus fellow=49.24, 95% CI of 30.22 to 68.27, p<0.001; WMDamblyopia versus control=54.51, 95% CI of 32.17 to 76.85, p<0.001). There were no differences between the fellow and control eyes (WMD=13.81, 95% CI of 1.16 to 28.77, p=0.071). Subgroup and metaregression analyses indicated that the OCT type was the main source of heterogeneity. Conclusions. The CT in the amblyopic eyes was thicker than that in the fellow and control eyes.

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