scholarly journals Analysis of Nursing Effect of Children with Henoch-Schonlein Purpura Based on the PDCA Nursing Model

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Shuai Qin ◽  
Dan Li ◽  
Bo Zhang
Keyword(s):  
Pediatric Patients ◽  
Gastrointestinal Symptoms ◽  
Recovery Process ◽  
Nursing Process ◽  
Henoch Schonlein Purpura ◽  
Intervention Effect ◽  
Speed Up ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura

By applying the PDCA model to the care of children with Henoch-Schonlein purpura, the nursing process can be divided into four stages: planning, execution, inspection, and treatment. According to the age characteristics and disease progression of pediatric patients, a complete nursing plan is formulated to efficiently implement the nursing content and improve the nursing effect. This paper studies the application of the PDCA nursing model in the nursing of children with Henoch-Schonlein purpura and statistically analyzes the disappearance of skin rash, joint pain relief, disappearance of urine protein, disappearance of gastrointestinal symptoms, etc. Finally, this paper combines the experiment to evaluate the intervention effect of this nursing model and provides reference for the follow-up care of children with Henoch-Schonlein purpura. From the results of experimental research, it can be known that PDCA nursing can improve the comfort of children with Henoch-Schonlein purpura, shorten the time for symptom disappearance, and speed up the recovery process.

scholarly journals Relevance of glomerular C4d deposition in pediatric patients with Henoch-Schönlein Purpura compared to IgA nephritis

2020 ◽  
Author(s):  
Kerstin Benz ◽  
Fulvia Ferrazzi ◽  
Matthias Galiano ◽  
Katja Sauerstein ◽  
Eva Vonbrunn ◽  
...  
Keyword(s):  
Pediatric Patients ◽  
Immunosuppressive Treatment ◽  
Henoch Schonlein Purpura ◽  
Gross Hematuria ◽  
Therapeutic Decisions ◽  
Renal Biopsies ◽  
Work Up ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura

Abstract Background IgA nephropathy (IgAN) is the most common primary glomerulonephritis (GN) in western countries and Henoch-Schönlein purpura nephritis (HSPN) is the most common form of vasculitis in childhood. Renal biopsy findings in both nephropathies are often similar and are characterized by mesangioproliferative GN with mesangial or mesangiocapillary IgA and C3c deposits. Aim of this study was to investigate the significances of glomerular C4d-deposition as discriminating factor between pediatric HSPN and IgAN Methods We retrospectively analysed patient records and renal biopsies from 53 pediatric patients from one single center with a median age of 10.5 years [range 2.3–18 years]. Twenty-two patients suffered from IgAN and 31 from HSPN. Work-up of all renal biopsies was performed using standard protocols including immunohistochemistry for C4d. Results Pediatric IgAN patients were older, presented more often with gross hematuria, lower rates of proteinuria and less endocapillary hypercellularity on histology compared to HSPN patients. However, the rate of glomerular C4d-positivity was not different between IgAN (36%) and HSPN (42%). Comparing all cases with positive versus negative glomerular C4d-staining, pediatric patients with glomerular C4d-positivity showed lesser gross hematuria, but slightly more proteinuria, hypertension, higher rates of immunosuppressive treatment and renal insufficiency at last follow-up compared to C4d-negative patients. Conclusions In conclusion, glomerular C4d does not differ between pediatric HSPN and IgAN as the rate of C4d-positivity was comparable in our study. However, in individual cases of pediatric IgAN and most importantly HSPN glomerular C4d-positivity may indicate a more severe course of the disease and might thus be helpful for therapeutic decisions.

scholarly journals Renal Outcomes of Childhood IgA Nephropathy and Henoch Schönlein Purpura Nephritis

2021 ◽  
Vol 73 (10) ◽  
pp. 687-694
Author(s):  
Thanaporn Chaiyapak ◽  
Anirut Pattaragarn ◽  
Suroj Supavekin ◽  
Nuntawan Piyaphanee ◽  
Kraisoon Lomjansook ◽  
...  
Keyword(s):  
Iga Nephropathy ◽  
Complete Recovery ◽  
Clinicopathological Characteristics ◽  
Henoch Schonlein Purpura ◽  
Renal Outcomes ◽  
Nephritic Syndrome ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura ◽  
Purpura Nephritis

Background: Henoch-Schönlein purpura nephritis (HSPN) is considered the systemic form of IgA nephropathy (IgAN). However, differing clinicopathological features and renal outcomes of children with IgAN and HSPN have been reported in some studies. Methods: This study retrospectively reviewed children with IgAN and HSPN younger than 18 years, between January 2004 and December 2015. The clinicopathological characteristics at diagnosis and the renal outcomes after at least 1 year of follow-up were compared between the two groups. Results: A total of 54 children, comprising 21 with IgAN and 33 with HSPN, were recruited. The children with HSPN were younger than the children with IgAN. Gross hematuria and nephritic syndrome at the initial presentation were more common in children with IgAN. Regarding the pathological findings, IgAN had greater chronicity than HSPN. After a median follow-up period from first presentation to renal outcomes measurement of 4.0 years (1.3-12.2) in children with IgAN and 4.2 years (1.1-11.4) in children with HSPN, the renal outcomes were better in the latter group. The incidence of chronic kidney disease (CKD) was 28.6% in children with IgAN and 6.1% in children with HSPN (p = 0.02). Complete recovery was observed more frequently in children with HSPN than in children with IgAN (57.1% in IgAN vs. 87.9% in HSPN, p = 0.01). Conclusions: Childhood IgAN has greater chronicity and worse renal outcomes than childhood HSPN, with a lower rate of complete recovery and a higher frequency of CKD. We recommend long-term follow-up for CKD in children with IgAN.

scholarly journals Adult Onset Henoch-Schonlein Purpura and Intussusception: A Rare Presentation

2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
Mridula Krishnan ◽  
Joseph Nahas
Keyword(s):  
Unusual Case ◽  
Surgical Intervention ◽  
Gastrointestinal Symptoms ◽  
Adult Onset ◽  
Henoch Schonlein Purpura ◽  
Rare Presentation ◽  
Prompt Treatment ◽  
Life Threatening ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura

We present an unusual case of a young 26-year-old male who was diagnosed with Henoch-Schonlein Purpura (HSP). Initial presentation was primarily mild gastrointestinal symptoms, which progressed to a life threatening intussusception and subsequently resolved with prompt glucocorticoid use rather than typical surgical intervention. Of importance, the patient’s initial gastrointestinal symptoms without associated skin manifestations made the diagnosis difficult. In conclusion, it is important to recognize uncommon presentations of HSP as it may lead to life threatening complications and surgical intervention may be avoided with prompt treatment.

scholarly journals Preliminary experience with tacrolimus in managing Henoch-Schönlein purpura featuring extrarenal symptoms refractory to conventional therapy

2020 ◽  
Author(s):  
Yan Chen ◽  
Haitao Bai ◽  
Yang Yang ◽  
Zhulan Lian
Keyword(s):  
Adverse Reaction ◽  
Multiple Organ ◽  
Screening Tests ◽  
Henoch Schonlein Purpura ◽  
Open Label ◽  
Organ Systems ◽  
Tacrolimus Therapy ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura

Abstract Background Henoch-Schönlein purpura (HSP) is the commonest vasculitis of childhood, affecting multiple organ systems. The extrarenal manifestations are prominent in some HSP cases, for which no standard treatment is available. It is interesting to examine the value of tacrolimus in such cases. Findings Seventeen children received tacrolimus to manage their refractory extrarenal symptoms of HSP in an open-label prospective study. Tacrolimus was administered at daily dose of 0.05–0.15 mg/kg. Tacrolimus was effective in all cases after treatment for 7–21 days. Tacrolimus treatment resulted in complete resolution of extrarenal symptoms in 15 cases, and partial resolution in the remaining 2 cases. During follow-up, skin purpura reoccurred in 2 cases, abdominal pain and loss of follow-up in 1 case each. Drug-related adverse reaction was not observed in any case. Abnormal renal function test was identified in 7 patients by urinary screening tests before tacrolimus therapy, 4 of them received renal biopsy. Only one patient showed evidence of renal impairment during follow-up. Conclusions Tacrolimus works quickly without drug-related adverse reaction in managing the HSP patients featuring recurrent extrarenal symptoms. Our preliminary experience suggests good clinical efficacy and safety of tacrolimus in such off-label use.

scholarly journals The Characteristics of Video Capsule Endoscopy in Pediatric Henoch–Schönlein Purpura with Gastrointestinal Symptoms

2020 ◽  
Author(s):  
Youhong Fang ◽  
Kerong Peng ◽  
Hong Zhao ◽  
Jie Chen
Keyword(s):  
Gastrointestinal Tract ◽  
Capsule Endoscopy ◽  
Gastrointestinal Symptoms ◽  
Video Capsule Endoscopy ◽  
Small Vessel Vasculitis ◽  
Henoch Schonlein Purpura ◽  
Laboratory Findings ◽  
Pass Through ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura

Abstract Background Henoch–Schönlein purpura (HSP) is a systemic small-vessel vasculitis that commonly affects gastrointestinal tract. The video capsule endoscopy (VCE) characteristics of pediatric HSP patients were rarely investigated. Methods Patients diagnosed with HSP by VCE examination at our hospital from February 2010 to January 2019 are analyzed. The clinical features, laboratory findings, and the characteristics of VCE findings are studied. Results There are 30 patients enrolled in this investigation from February 2010 to January 2020. The mean age of these patients is 96.9±35.8 months, and the most frequent finding of VCE is mucosal erosion, which account for 69 % of the patients, and followed by mucosal erythema or petechia accounted for 79.3 % of the patients. Regarding to the disease location detected by endoscopy, jejunum is the most common involved part of the gastrointestinal tract in pediatric HSP patients. All the patients had jejunum involved except in one patient the VCE did not pass through the pylorus. One third of the patients involved the descent part of duodenum. No side effects are observed in this study. Conclusions VCE is safe and effective in the diagnosis of gastrointestinal involved HSP patients with or without typical skin purpura. Jejunum is the most common involve location in gastrointestinal.

Sign in / Sign up

Export Citation Format

Share Document