scholarly journals A Report of 61 Cases of Retroperitoneal Laparoscopic Nephron-Sparing Surgery and Factors Affecting Postoperative Renal Function

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Yao Song ◽  
Songqiang Pang ◽  
Jinqiang Yang ◽  
Sen Li ◽  
Yaqiang He ◽  
...  
Keyword(s):  
Renal Function ◽  
Operation Time ◽  
Nephron Sparing Surgery ◽  
Renal Tumors ◽  
Tumor Diameter ◽  
Related Factors ◽  
Factors Affecting ◽  
Postoperative Renal Function ◽  
Nephron Sparing ◽  
The Mean

Objective. To explore the situation of 61 patients with renal tumors who underwent retroperitoneal laparoscopic nephron-sparing surgery (RLNSS) and the factors affecting postoperative renal function. Methods. A total of 61 patients with renal tumors who underwent RLNSS in our hospital from January 2018 to January 2021 were included in this study. All patients were treated with RLNSS. The clinical data of patients were recorded. Before operation and 3 months after operation, the change value of glomerular filtration rate (ΔGFR) was measured by the Gates method. Multivariate linear regression was used to analyze the related factors affecting postoperative renal function. Results. All 61 patients successfully completed the operation. The mean operative time was 60–150 min‚ average (98.75 ± 14.38) min. The estimated intraoperative blood loss was 20–310 ml‚ average (107.93 ± 68.55) ml. Intraoperative warm ischemia time (WIT) was 0–39 min, with an average of (21.16 ± 6.47) min. All patients’ pathological margins were negative after operation. In all patients, there were 5 postoperative complications, including 2 cases of renal wound bleeding (3.28%), 1 case of hematuria (1.64%), 1 case of urinary fistula (1.64%), and 1 case of subcutaneous emphysema (1.64%). There were significant differences in tumor diameter, preoperative GFR, operation time and WIT ( P < 0.05 ). Multivariate analysis showed that tumor diameter, preoperative GFR, and WIT were all factors affecting the postoperative renal function of patients with RLNSS ( P < 0.05 ). Conclusion. RLNSS has a good curative effect on patients with renal tumor, and tumor diameter, preoperative GFR, and WIT were all factors affecting the postoperative renal function of patients with RLNSS.

Predictors of renal function in nephron sparing surgery for renal cell carcinoma in solitary kidneys

2009 ◽  
Vol 27 (15_suppl) ◽  
pp. e16045-e16045
Author(s):  
M. Wosnitzer ◽  
D. J. Lee ◽  
A. J. Hirsch ◽  
J. M. McKiernan
Keyword(s):  
Renal Cell Carcinoma ◽  
Renal Failure ◽  
Renal Function ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Tumor Stage ◽  
Nephron Sparing Surgery ◽  
Tumor Diameter ◽  
Nephron Sparing ◽  
The Mean

e16045 Background: Partial nephrectomy (PN) is an effective option for the treatment of renal cell carcinoma (RCC) in patients who need to preserve renal function. However, the oncologic safety and functional outcome after PN in solitary kidneys have not been fully examined. We assessed the outcomes after PN, and evaluated predictors of post-operative renal function. Methods: A retrospective analysis of the Columbia Urologic Oncology database found 1327 patients were treated for RCC from 1988 - 2008, of whom 38 consecutive patients underwent PN on a solitary kidney. Glomerular filtration rate (GFR) was estimated with the Modification of Diet in Renal Disease (MDRD) equation. Severe chronic kidney disease (CKD) and renal failure were defined as GFR of 15–30 cc/min/1.73m2 and GFR<15, respectively. Cox proportional hazards regression methods were used. Results: The study group included 30 men and 8 women with unilateral RCC. The mean age was 63.2 years (range 35–83). The mean estimated blood loss was 465cc, the mean tumor diameter was 3.9cm, and 6 (17%) of the patients had a positive surgical margin. 9 patients (30%) had recurrence of RCC at a mean of 23 months postoperatively. Recurrence occurred in the kidneys of 4 patients, lung in 3 patients, bone in 3 patients, and the ipsilateral adrenal gland in one patient. The mean preoperative GFR was 55.6, and the GFR decreased postoperatively by an average of 14.2%. No patients required postoperative hemodialysis. Preoperative GFR (HR=1.01, p<0.01) and the volume of kidney removed (HR=0.93, p=0.01) were associated with severe CKD and renal failure on a univariate Cox regression analysis, but were not independent predictors after adjusting for age, race, tumor stage and grade. Preoperative GFR, volume removed, age, tumor stage or grade were not independent predictors of RCC recurrence. Conclusions: PN in solitary kidneys pose difficult challenges for surgical and clinical management. Nephron sparing surgery for the treatment of RCC is feasible with acceptable morbidity and renal function outcome. The volume of renal parenchyma removed and the preoperative GFR are associated with renal function loss several months after surgery, and may be useful in predicting long-term renal function. No significant financial relationships to disclose.

scholarly journals Renal function after nephron-sparing surgery for renal tumors

2012 ◽  
Vol 65 ◽  
pp. 14-16
Author(s):  
Roman Sosnowski ◽  
Małgorzata Benke ◽  
Tomasz Demkow ◽  
Marcin Ligaj ◽  
Wojciech Michalski
Keyword(s):  
Renal Function ◽  
Nephron Sparing Surgery ◽  
Renal Tumors ◽  
Nephron Sparing

scholarly journals A retrospective study of open and endoscopic nephron sparing surgery in the treatment of complex renal tumors

2021 ◽  
Vol 37 (4) ◽  
Author(s):  
Ting-ting Li ◽  
Jia Feng ◽  
Yan-ling Li ◽  
Qian Sun
Keyword(s):  
Operation Time ◽  
Nephron Sparing Surgery ◽  
Renal Tumors ◽  
Warm Ischaemia ◽  
Ischaemia Time ◽  
Renal Tumours ◽  
Nephron Sparing ◽  
Function Recovery ◽  
And Control ◽  
Warm Ischaemia Time

Objective: To investigate clinical outcomes of open and retroperitoneal laparoscopic nephron-sparing surgery in the treatment of complex renal tumours. Methods: A retrospective case study was conducted. Patients with complex renal tumours admitted to our hospital between January 2018 and September 2019 were enrolled; the included patients (n=40) were divided into the observation group (open partial nephrectomy, n=20) and control group (laparoscopic partial nephrectomy, n=20) according to operation modes. The operation time, renal warm ischaemia time, intraoperative blood loss, renal pedicle blocking time, intestinal function recovery time, postoperative hospital stay, and postoperative complications were recorded. Results: Significant differences were noted regarding renal warm ischaemia time, renal pedicle blocking time, intraoperative blood loss, operation time, and postoperative hospital stay between the observation and control groups (P<0.05); however, no significant difference was observed in intestinal function recovery time and postoperative drainage days (P>0.05). Conclusion: Open surgery remains the recommended surgical method for the treatment of few complex tumours in the renal hilus region and has gradually become the renal surgery of choice at present, although laparoscopic surgery has evolved tremendously. doi: https://doi.org/10.12669/pjms.37.4.3457 How to cite this:Li TT, Feng J, Li YL, Sun Q. A retrospective study of open and endoscopic nephron sparing surgery in the treatment of complex renal tumors. Pak J Med Sci. 2021;37(4):---------. doi: https://doi.org/10.12669/pjms.37.4.3457 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

RENAL FUNCTION ADAPTATION IN CHILDREN WITH UNILATERAL RENAL TUMORS TREATED WITH NEPHRON SPARING SURGERY OR NEPHRECTOMY

2005 ◽  
Vol 174 (4 Part 1) ◽  
pp. 1404-1408 ◽  
Author(s):  
FRANCESCO COZZI ◽  
AMALIA SCHIAVETTI ◽  
FRANCESCO MORINI ◽  
AUGUSTO ZANI ◽  
MARCO GAMBINO ◽  
...  
Keyword(s):  
Renal Function ◽  
Nephron Sparing Surgery ◽  
Renal Tumors ◽  
Nephron Sparing

scholarly journals Nephron sparing surgery for renal tumors-comparison of off-clamp partial nephrectomy with hilar clamping

2020 ◽  
Vol 36 (3) ◽  
Author(s):  
Imran Khan Jalbani ◽  
Syed Mohammad Nazim ◽  
Maria Ahmed ◽  
Farhat Abbas
Keyword(s):  
Renal Function ◽  
Blood Loss ◽  
Partial Nephrectomy ◽  
Nephron Sparing Surgery ◽  
Surgical Margins ◽  
Renal Tumors ◽  
Open Partial Nephrectomy ◽  
Nephrometry Score ◽  
Nephron Sparing ◽  
Significant Difference

Background and Objective: Open partial nephrectomy (PN) is still considered gold standard procedure for T1 localized renal tumors. Conventional technique involves clamping of the renal artery with or without vein however, renal ischemia produces a certain level of damage to the kidneys. This study aims to investigate potential effect of off-clamp vs. hilar clamping PN on renal function. Methods: This is a retrospective cohort study of patients who underwent unilateral, open partial nephrectomy for renal tumors b/w January 2009 December 2016 at our institution. A total of 90 partial nephrectomies were performed of which 65 cases were eligible for analysis. Non clamping technique was used in 43 while clamp was applied in 22 patients. Variables studied were patients’ demographics, clinical variables, the laterality, tumors size and location, R.E.N.A.L nephrometry score, blood loss, tumor histology and surgical margins. Patients’ renal function (serum creatinine and eGFR) were determined pre-operatively, at 3 and 12 months follow up. Data was analyzed on SPSS v. 22. Results: Both the groups were comparable with regards to pre-operative renal function. Mean radiological size of tumor was 4.71±1.31 and 3.81±1.0 (0.003) in two groups respectively. Mean R.E.N.A.L nephrometry score was 6.1±1.5 in off-clamp group compared to 7.05±1.7 in clamp group (p=0.04). No statistically significant difference was found in operative duration, blood loss, positive surgical margins and intra/ peri-operative complications. At three months and one year, renal function was better preserved in non-clamp group compared to clamp group (p=0.001 and 0.007 respectively). Conclusion: Off clamp open partial nephrectomy is safe and feasible option leading to less decline in renal function. doi: https://doi.org/10.12669/pjms.36.3.1533 How to cite this:Jalbani IK, Nazim SM, Ahmed M, Abbas F. Nephron sparing surgery for renal tumors- comparison of off-clamp partial nephrectomy with hilar clamping. Pak J Med Sci. 2020;36(3):---------. doi: https://doi.org/10.12669/pjms.36.3.1533 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

ISCHEMIC DAMAGE OF NEPHRON-SPARING SURGERY ON RENAL FUNCTION

2008 ◽  
Vol 179 (4S) ◽  
pp. 327-327
Author(s):  
Yasuhito Funahashi ◽  
Ryohei Hattori ◽  
Osamu Kamihira ◽  
Tokunori Yamamoto ◽  
Momokazu Gotoh
Keyword(s):  
Renal Function ◽  
Nephron Sparing Surgery ◽  
Ischemic Damage ◽  
Nephron Sparing
Sign in / Sign up

Export Citation Format

Share Document