scholarly journals A retrospective study of open and endoscopic nephron sparing surgery in the treatment of complex renal tumors

2021 ◽  
Vol 37 (4) ◽  
Author(s):  
Ting-ting Li ◽  
Jia Feng ◽  
Yan-ling Li ◽  
Qian Sun
Keyword(s):  
Operation Time ◽  
Nephron Sparing Surgery ◽  
Renal Tumors ◽  
Warm Ischaemia ◽  
Ischaemia Time ◽  
Renal Tumours ◽  
Nephron Sparing ◽  
Function Recovery ◽  
And Control ◽  
Warm Ischaemia Time

Objective: To investigate clinical outcomes of open and retroperitoneal laparoscopic nephron-sparing surgery in the treatment of complex renal tumours. Methods: A retrospective case study was conducted. Patients with complex renal tumours admitted to our hospital between January 2018 and September 2019 were enrolled; the included patients (n=40) were divided into the observation group (open partial nephrectomy, n=20) and control group (laparoscopic partial nephrectomy, n=20) according to operation modes. The operation time, renal warm ischaemia time, intraoperative blood loss, renal pedicle blocking time, intestinal function recovery time, postoperative hospital stay, and postoperative complications were recorded. Results: Significant differences were noted regarding renal warm ischaemia time, renal pedicle blocking time, intraoperative blood loss, operation time, and postoperative hospital stay between the observation and control groups (P<0.05); however, no significant difference was observed in intestinal function recovery time and postoperative drainage days (P>0.05). Conclusion: Open surgery remains the recommended surgical method for the treatment of few complex tumours in the renal hilus region and has gradually become the renal surgery of choice at present, although laparoscopic surgery has evolved tremendously. doi: https://doi.org/10.12669/pjms.37.4.3457 How to cite this:Li TT, Feng J, Li YL, Sun Q. A retrospective study of open and endoscopic nephron sparing surgery in the treatment of complex renal tumors. Pak J Med Sci. 2021;37(4):---------. doi: https://doi.org/10.12669/pjms.37.4.3457 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals RESULTS OF NEPHRON-SPARING SURGERY OF INTRAPARENCHYMAL RENAL TUMORS

2020 ◽  
Vol 20 (2) ◽  
pp. 96-101
Author(s):  
G.G. Khareba ◽  
V.M. Lisovyi ◽  
D.V. Shchukin
Keyword(s):  
Progression Free Survival ◽  
Term Treatment ◽  
Current Approach ◽  
Nephron Sparing Surgery ◽  
Renal Tumors ◽  
Large Size ◽  
Renal Tumours ◽  
Nephron Sparing ◽  
Long Term Treatment ◽  
Treatment Technologies

Surgical treatment is the main therapy for patients with renal cell carcinoma. The current approach in the treatment of kidney tumours has become widely introduced into nephron-sparing surgery. This approach is usually applied in cases of complex surgeries for large-size tumours with intravenous extension, multifocal, and intraparenchymal renal tumours. The purpose of the study was to investigate the results of nephron-sparing surgery for intraparenchymal renal tumours. Material and methods. The results were obtained in the process of nephron-sparing surgery treatment of 701 patients with renal tumours. After the distribution of all patients according to the criterion of "intraparenchymal renal tumours", we assessed 27 (3,9%) cases of nephron-sparing surgery. There were also 674 (96,1%) patients with exophytic renal tumors. Results. We managed to obtain the information about long-term treatment outcomes from 606 (86.4%) patients. There were 25 (4,1%) patients with intraparenchymal renal tumors. The observation of patients showed that there were cases of death and disease progression for various reasons during 46.5±2.1 months on average. The results of the comparative statistical analysis showed that the 5-year overall survival among patients with intraparenchymal renal tumors made up 88.0% of the cases and among the patients with exophytic renal tumors it was 94.8%. The differences were not significant (p> 0.430). At the same time, the 5-year overall progression-free survival was obtained in 88.9% of the patients with intraparenchymal renal tumors and in 95.2% (p <0.041) of patients with exophytic renal tumors. Conclusion. The problem of nephron-sparing treatment of intraparenchymal renal tumors is an urgent issue. Research has shown that such tumors are complex for nephron-sparing surgery, require complex treatment technologies that affect surgical results. At the same time, positive oncological results demonstrate that nephron-sparing treatment is an effective method of treating fully intraparenchymal renal tumors.

scholarly journals A Report of 61 Cases of Retroperitoneal Laparoscopic Nephron-Sparing Surgery and Factors Affecting Postoperative Renal Function

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Yao Song ◽  
Songqiang Pang ◽  
Jinqiang Yang ◽  
Sen Li ◽  
Yaqiang He ◽  
...  
Keyword(s):  
Renal Function ◽  
Operation Time ◽  
Nephron Sparing Surgery ◽  
Renal Tumors ◽  
Tumor Diameter ◽  
Related Factors ◽  
Factors Affecting ◽  
Postoperative Renal Function ◽  
Nephron Sparing ◽  
The Mean

Objective. To explore the situation of 61 patients with renal tumors who underwent retroperitoneal laparoscopic nephron-sparing surgery (RLNSS) and the factors affecting postoperative renal function. Methods. A total of 61 patients with renal tumors who underwent RLNSS in our hospital from January 2018 to January 2021 were included in this study. All patients were treated with RLNSS. The clinical data of patients were recorded. Before operation and 3 months after operation, the change value of glomerular filtration rate (ΔGFR) was measured by the Gates method. Multivariate linear regression was used to analyze the related factors affecting postoperative renal function. Results. All 61 patients successfully completed the operation. The mean operative time was 60–150 min‚ average (98.75 ± 14.38) min. The estimated intraoperative blood loss was 20–310 ml‚ average (107.93 ± 68.55) ml. Intraoperative warm ischemia time (WIT) was 0–39 min, with an average of (21.16 ± 6.47) min. All patients’ pathological margins were negative after operation. In all patients, there were 5 postoperative complications, including 2 cases of renal wound bleeding (3.28%), 1 case of hematuria (1.64%), 1 case of urinary fistula (1.64%), and 1 case of subcutaneous emphysema (1.64%). There were significant differences in tumor diameter, preoperative GFR, operation time and WIT ( P < 0.05 ). Multivariate analysis showed that tumor diameter, preoperative GFR, and WIT were all factors affecting the postoperative renal function of patients with RLNSS ( P < 0.05 ). Conclusion. RLNSS has a good curative effect on patients with renal tumor, and tumor diameter, preoperative GFR, and WIT were all factors affecting the postoperative renal function of patients with RLNSS.

Nephron-Sparing Surgery for Central Renal Tumors

2008 ◽  
pp. 341-344
Author(s):  
Sascha Pahernik ◽  
Joachim W. Thüroff
Keyword(s):  
Nephron Sparing Surgery ◽  
Renal Tumors ◽  
Nephron Sparing

scholarly journals 1083: Laparoscopic Nephron-Sparing Surgery for Centrally Located Solid Renal Tumors

2005 ◽  
Vol 173 (4S) ◽  
pp. 294-294 ◽  
Author(s):  
Igor Frank ◽  
Jose R. Colombo ◽  
Mauricio Rubenstein ◽  
Jihad H. Kaouk ◽  
Inderbir S. Gill
Keyword(s):  
Nephron Sparing Surgery ◽  
Renal Tumors ◽  
Nephron Sparing

349Elective nephron sparing surgery for renal tumours — Long-term outcome

2005 ◽  
Vol 4 (3) ◽  
pp. 90
Author(s):  
S. Pahemik ◽  
R. Gillitzer ◽  
C. Hampel ◽  
S. Melchior ◽  
J. Thuroff
Keyword(s):  
Nephron Sparing Surgery ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Renal Tumours ◽  
Nephron Sparing

scholarly journals Multifocal Renal Cell Carcinoma: Clinicopathologic Features and Outcomes for Tumors≤4 cm

2008 ◽  
Vol 2008 ◽  
pp. 1-7 ◽  
Author(s):  
Paul L. Crispen ◽  
Christine M. Lohse ◽  
Michael L. Blute
Keyword(s):  
Nephron Sparing Surgery ◽  
Renal Tumors ◽  
Renal Unit ◽  
Clinicopathologic Features ◽  
Cross Sectional ◽  
Free Survival ◽  
Distant Metastasis Free Survival ◽  
Nephron Sparing ◽  
Multifocal Disease ◽  
Previous Series

A significant increase in the incidental detection of small renal tumors has been observed with the routine use of cross-sectional abdominal imaging. However, the proportion of small renal tumors associated with multifocal RCC has yet to be established. Here then, we report our experience with the treatment of multifocal RCC in which the primary tumor was ≤4 cm. In our series of 1113 RCC patients, 5.4% (60/1113) had multifocal disease at the time of nephrectomy. Discordant histology was present in 17% (10/60) of patients with multifocal RCC. Nephron sparing surgery was utilized more frequently in patients with solitary tumors. Overall, cancer-specific, and distant metastasis-free survival appeared to be similar between multifocal and solitary tumors. These findings are consistent with previous series which evaluated multifocal RCC with tumors >4 cm. With the known incidence of multifocality RCC, careful inspection of the entire renal unit should be performed when performing nephron sparing surgery.

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