scholarly journals Single-Photon Emission Computed Tomography Image-Assisted Diagnosis of Thyroid Diseases under Convolutional Network Neural Algorithm

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Shaobo Chen ◽  
Yinzhen Pi ◽  
Haiyan Gong ◽  
Huaijun Wang ◽  
Shu Liu

The aim of this study was to investigate the value of single-photon emission computed tomography (SPECT) based on the convolutional neural network (CNN) algorithm in thyroid diseases. Thirty-five patients with thyroid disease from the hospital were selected as the observation group, and another 35 healthy volunteers were selected as the control group. The constructed model of SPECT based on the CNN algorithm was compared with the backpropagation neural network (BPNN) algorithm, which was then applied to the SPECT of 35 patients with thyroid disease. It turned out that as the number of iterations increased, the parameter training of CNN was gradually sufficient, the network model was continuously optimized, and the accuracy gradually increased. From the data results, the Dice value of the proposed CNN algorithm was higher than that of the BPNN algorithm and the segmentation effect was relatively good. The visual index of the thyroid/neck of the observation group (2.68 ± 1.32) was remarkably inferior to that of the control group (12.347.54) ( P < 0.05 ). The visual index of the thyroid/submandibular gland in the observation group (1.02 ± 0.41) was remarkably inferior to that of the control group (8.89 ± 4.86) ( P < 0.05 ). The visual index of the thyroid/parotid gland in the observation group (1.04 ± 0.58) was remarkably inferior to that of the control group (8.53 ± 4.25) ( P < 0.05 ). In addition, 99mTcO4-SPECT had a sensitivity of 95.2%, a specificity of 90.3%, and an accuracy of 91.5% in the diagnosis of thyroid diseases. The area under the curve of the receiver operating characteristic curve for 99mTcO4-SPECT diagnosis of thyroid disease is 0.958, and the 95% confidence interval is 0.834∼1. In summary, the SPECT based on the CNN algorithm proposed in this study has a good segmentation effect and can accurately locate the anatomical information of thyroid diseases, which can replace the traditional diagnostic methods for the diagnosis of thyroid diseases.

Diagnostics ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. 57
Author(s):  
Ji Lee ◽  
Hee-Sung Song ◽  
Jae Choi ◽  
Chang Hyun ◽  
Sang Lee ◽  
...  

Technetium (Tc)-99m-methoxyisobutylisonitrile (MIBI) single photon-emission computed tomography/computed tomography (SPECT/CT) is now being used increasingly for preoperative localization of parathyroid adenomas. Tc-99m-MIBI scintigraphy in a 52-year-old man with a diagnosis of primary hyperparathyroidism revealed two focal areas with retention of radioactivity in the left lobe of the thyroid gland on the delayed phase of MIBI SPECT/CT but no significant focal radioactive uptake on MIBI planar images. The patient subsequently underwent left partial parathyroidectomy. Histological analysis identified one lesion to be thyroid hyperplasia and the other to be parathyroid adenoma. This case demonstrates the value of MIBI SPECT/CT for localization of a parathyroid lesion when compared with planar images and that false-positive findings can lead to misdiagnosis in a patient with coexisting thyroid disease. An appropriate diagnostic work-up that includes Tc-99m MIBI SPECT/CT in addition to ultrasonography is helpful for an accurate diagnosis in patients with concomitant thyroid disease.


2020 ◽  
Vol 9 (2) ◽  
pp. 399
Author(s):  
Pyung Goo Cho ◽  
Tae Woo Kim ◽  
Gyu Yeul Ji ◽  
Sang Hyuk Park ◽  
Mi Jin Yun ◽  
...  

A cervicogenic headache (CEH) is difficult to diagnose due to its varied pathology. We evaluated the usefulness of single-photon emission computed tomography/computed tomography (SPECT/CT) in diagnosing CEH and its interventional treatment. Retrospectively, 23 patients diagnosed with CEH between March 2016 to August 2018 were allocated to SPECT/CT (n = 11) and control (n = 12) groups. The SPECT/CT group was further stratified into SPECT/CT(+) and SPECT/CT(-) groups according to the presence of positive findings. Patients in the SPECT/CT group underwent an intra-articular injection at a radiologically verified lesion site, whereas those in the control group underwent third occipital nerve block. Clinical outcomes were evaluated with the visual analog scale (VAS), neck disability index (NDI), and global perceived effect (GPE) scale at baseline, and at one, three, and six months postoperatively. The SPECT/CT group showed less VAS, NDI, and GPE scores at six months postoperatively (2.91 ± 2.30 vs. 4.42 ± 1.62, p = 0.08; 38.00 ± 16.54 vs. 48.7 ± 12.40, p = 0.093; 2.00 ± 1.41 vs. 3.17 ± 1.11, p = 0.039). Successful responders at six months postoperatively were higher in the SPECT/CT(+) group than in the control group (75% vs. 0%). SPECT/CT can identify arthritic changes and accurately define therapeutic targets.


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