Oral Isotretinoin Therapy in Recalcitrant Molluscum Contagiosum in an Immunocompromised Patient

Molluscum contagiosum is a viral infection caused by the Poxvirus characterized by multiple umbilicated papules. It is common in children and can be present at any body site. Severe molluscum is common in immunocompromised patients. We report a 20-year-old HIV-positive individual with widespread molluscum contagiosum, recalcitrant to topical therapy, under antiretroviral therapy, who was treated with oral isotretinoin and had a dramatic outcome. Although studies are needed to confirm the effectiveness of oral isotretinoin therapy in molluscum contagiosum, its easy availability, cost, and excellent safety profile appear to offer a promising therapeutic option.

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Cerebral Hydatid Cyst in a Young Immunocompromised Patient in Parakou

Journal of Neurosciences in Rural Practice ◽

10.4103/jnrp.jnrp_76_18 ◽

2018 ◽

Vol 09 (04) ◽

pp. 622-624

Author(s):

Thierry Adoukonou ◽

Donald Accrombessi ◽

Mendinatou Agbetou

Keyword(s):

Immunocompromised Patient ◽

Motor Deficit ◽

Hiv Positive ◽

Neurosurgical Procedure ◽

Generalized Seizures ◽

Immunodeficiency Virus ◽

Cerebral Hydatid Cyst ◽

Initial Improvement ◽

Inflammatory Syndrome ◽

Annular Calcification

ABSTRACTWe report the case of a 30-year-old human immunodeficiency virus (HIV)-positive HIV patient who was poorly followed. She was admitted on November 30, 2017, for the management of febrile encephalitis syndrome with motor deficit of the left hemicorps and generalized seizures. In biology, we found a nonspecific inflammatory syndrome. The cerebral imaging without and with injection found a cystic formation multilobed right fronto-parietal of approximately 83 mm × 62 mm, the presence of an annular calcification of approximately 8 mm with a commitment under falcator, and a contralateral ventricle dilation. Treatment with antiepileptic, antibiotic, antiparasitic, and corticosteroid therapy was marked by death the day before the neurosurgical procedure after initial improvement.

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The Role of QuantiFERON-TB Gold Plus in Mycobacterium Tuberculosis Detection in a Severe HIV Immunocompromised Patient—Case Report

Pathogens ◽

10.3390/pathogens10111523 ◽

2021 ◽

Vol 10 (11) ◽

pp. 1523

Author(s):

Florentina Dumitrescu ◽

Cătălina-Gabriela Pisoschi ◽

Vlad Pădureanu ◽

Andreea Cristina Stoian ◽

Livia Dragonu ◽

...

Keyword(s):

Mycobacterium Tuberculosis ◽

Immunocompromised Patient ◽

Symptomatic Treatment ◽

Pneumocystis Pneumonia ◽

Hiv Positive ◽

Patient Case ◽

Mycobacterium Tuberculosis Infection ◽

Antituberculosis Therapy ◽

Antituberculosis Treatment

Tuberculosis (TB) is an important opportunistic infection in HIV-positive people. We are reporting a case of a 31-year-old HIV-infected patient who was hospitalized in July 2021 for dyspnea, cough with mucopurulent sputum and asthenia. He was confirmed to have Serratia liquefaciens pneumonia and acute respiratory failure. The evolution was unfavorable despite the antibiotic, pathogenic and symptomatic treatment. Because the patient had severe immunosuppression (CD4 count = 37 cell/mm3), we used QuantiFERON-TB Gold Plus for the detection of the Mycobacterium tuberculosis infection. The antituberculosis therapy was initiated, which resulted in a significant improvement of the general condition and the patient was discharged with the recommendation to continue antiretroviral therapy, antituberculosis treatment and Trimethoprim/Sulfamethoxazole—single tablet daily for the prophylaxis of Pneumocystis pneumonia.

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Giant Molluscum Contagiosum in an HIV positive patient

International Journal of Infectious Diseases ◽

10.1016/j.ijid.2015.07.021 ◽

2015 ◽

Vol 38 ◽

pp. 153-155 ◽

Cited By ~ 7

Author(s):

Carlos E. Pérez-Díaz ◽

Carlos A. Botero-García ◽

Maria C. Rodríguez ◽

Álvaro A. Faccini-Martínez ◽

Omar-Javier Calixto ◽

...

Keyword(s):

Molluscum Contagiosum ◽

Positive Patient ◽

Hiv Positive

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Beware of cryptococcomas when treating Cryptococcal meningitis

Journal of Neurology & Stroke ◽

10.15406/jnsk.2020.10.00435 ◽

2020 ◽

Vol 10 (5) ◽

pp. 183-184

Author(s):

Rafael Ferreira Nascimento ◽

Diogo Raposo André, ◽

Fabiana Gouveia ◽

Nancy Faria ◽

Ana Paula Reis

Keyword(s):

Immunocompromised Patient ◽

Brain Mri ◽

Hiv Positive ◽

Rare Presentation ◽

Neck Stiffness ◽

Viral Loads ◽

Hiv Rna ◽

Neurological Exam ◽

History Of ◽

The Brain

Introduction: The authors describe a rare presentation of central nervous system cryptococcosis in an immunocompromised patient. Case description: An HIV-positive patient, with poor adherence to the treatment, presented with a seventeen days history of severe headache. On the neurological exam there was only evidence of neck stiffness, he had a CD4 count of 23 cells/μl and plasma HIV RNA viral loads of 364,000 copies/ml. Lumbar puncture revealed positive for cryptococcal antigen virus and so treatment with amphotericin B was started. During his admission the patient developed an expressive aphasia with visual hallucinations and the brain MRI revealed cerebral cryptococcomas. After 98 days of treatment general and neurological examination was normal and the patient was discharged home. Conclusion: This case highlights a rare and severe complication of Cryptococcus neoformans infection in immunocompromised patients.

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Radiological-Pathological Correlation in Plasmablastic Lymphoma in an Immunocompromised Patient

Case Reports in Ophthalmological Medicine ◽

10.1155/2018/4746050 ◽

2018 ◽

Vol 2018 ◽

pp. 1-3

Author(s):

A. Moramarco ◽

M. Marenco ◽

M. La Cava ◽

A. Lambiase

Keyword(s):

Drug User ◽

Fungal Infections ◽

Immunocompromised Patient ◽

Poor Response ◽

Plasmablastic Lymphoma ◽

Response To Treatment ◽

Hiv Positive ◽

Radiological Features ◽

Pathological Conditions ◽

Aggressive Form

Plasmablastic lymphoma (PBL) is a malignant, rare, and aggressive form of non-Hodgkin’s lymphoma with poor response to treatment that most commonly involves the oral mucosa of immunodeficient patients. The orbit might be primarily or secondarily involved; on the other hand other pathological conditions, i.e., fungal infections, may localize in the orbit in both immunocompromised patients and drug user, which might have similar radiological features. We describe the clinical, radiological, and pathological features of an orbital plasmablastic lymphoma (PBL) in an immunocompromised HIV positive drug user patient.

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Acute Achilles tendonitis following oral isotretinoin therapy for acne vulgaris

Clinical and Experimental Dermatology ◽

10.1111/j.1365-2230.1992.tb02159.x ◽

1992 ◽

Vol 17 (4) ◽

pp. 250-251 ◽

Cited By ~ 14

Author(s):

W. W. BOTTOMLEY ◽

W.J. CUNLIFFE

Keyword(s):

Acne Vulgaris ◽

Oral Isotretinoin ◽

Achilles Tendonitis ◽

Isotretinoin Therapy

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EBV-associated perianal Hodgkin's disease in an HIV-positive individual

American Journal of Hematology ◽

10.1002/1096-8652(200101)66:1<42::aid-ajh1006>3.0.co;2-v ◽

2000 ◽

Vol 66 (1) ◽

pp. 42-45 ◽

Cited By ~ 14

Author(s):

Michelle Sapp ◽

Bayardo Perez-Ordonez ◽

Fred Brenneman ◽

Kevin Imrie ◽

Isabella Morava-Protzner ◽

...

Keyword(s):

Hodgkin's Disease ◽

Hodgkin’S Disease ◽

Hiv Positive ◽

Positive Individual

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A tale of resistant Escherichia coli epididymo-orchitis in an HIV-positive individual

Journal of Clinical Urology ◽

10.1177/2051415815618055 ◽

2016 ◽

Vol 10 (3) ◽

pp. 259-260

Author(s):

Kanchana Seneviratne ◽

Christopher Bignell

Keyword(s):

Escherichia Coli ◽

Treatment Failure ◽

Hiv Positive ◽

Sexually Transmitted ◽

The Past ◽

Positive Individual

Epididymo-orchitis in men > 35 years is more frequently associated with enteric rather than sexually transmitted organisms. We describe a case for which we did not find any reports of this type of treatment failure in the past.

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