Giant Cell Urothelial Carcinoma of Bladder
Keyword(s):
Giant cell urothelial carcinoma is a rare variant of bladder cancer recognized by the current World Health Organization classification of urologic tumours. It is an aggressive tumour with a poor prognosis that usually presents at an advanced stage. It is characterized histologically by pleomorphic giant cells. We discuss a case of giant cell urothelial carcinoma presenting at an early stage in a previously well 62-year-old woman. Histology showed a tumour comprising pancytokeratin positive bizarre mononuclear and multi-nuclear giant cells admixed with areas of conventional urothelial carcinoma and carcinoma in situ. Three-month follow-up cystoscopy and magnetic resonance imaging showed no evidence of recurrence or pelvic lymphadenopathy.
2001 ◽
Vol 18
(6)
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pp. 1059-1068
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2020 ◽
Vol 21
(3)
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pp. 171-181
2018 ◽
Vol 143
(6)
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pp. 711-721
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Keyword(s):
2018 ◽
Vol 142
(9)
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pp. 1017-1017
2006 ◽
Vol 130
(8)
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pp. 1233-1235