Enhanced Radiation-Induced Cell Killing and Prolongation of γH2AX Foci Expression by the Histone Deacetylase Inhibitor MS-275

Kevin Camphausen; William Burgan; Michael Cerra; Kelli A. Oswald; Jane B. Trepel; Min-Jung Lee; Philip J. Tofilon

doi:10.1158/0008-5472.can-03-2630

Enhanced Radiation-Induced Cell Killing and Prolongation of γH2AX Foci Expression by the Histone Deacetylase Inhibitor MS-275

Cancer Research ◽

10.1158/0008-5472.can-03-2630 ◽

2004 ◽

Vol 64 (1) ◽

pp. 316-321 ◽

Cited By ~ 139

Author(s):

Kevin Camphausen ◽

William Burgan ◽

Michael Cerra ◽

Kelli A. Oswald ◽

Jane B. Trepel ◽

...

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Cell Killing ◽

Γh2ax Foci ◽

Deacetylase Inhibitor ◽

Radiation Induced

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Novel Three-Pronged Strategy to Enhance Cancer Cell Killing in Glioblastoma Cell Lines: Histone Deacetylase Inhibitor, Chemotherapy, and Oncolytic Adenovirus dl520

Human Gene Therapy ◽

10.1089/hum.2005.17.ft-158 ◽

2005 ◽

Vol 0 (0) ◽

pp. 051215125756001

Author(s):

Alexa Bieler ◽

Klaus Mantwill ◽

Tanja Dravits ◽

Alexandra Bernshausen ◽

Gabriel Glockzin ◽

...

Keyword(s):

Histone Deacetylase ◽

Cell Lines ◽

Cancer Cell ◽

Histone Deacetylase Inhibitor ◽

Cell Killing ◽

Oncolytic Adenovirus ◽

Glioblastoma Cell ◽

Deacetylase Inhibitor ◽

Glioblastoma Cell Lines

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Histone Deacetylase Inhibitor Sodium Butyrate Enhances the Cell Killing Effect of Psoralen plus UVA by Attenuating Nucleotide Excision Repair

Cancer Research ◽

10.1158/0008-5472.can-08-2546 ◽

2009 ◽

Vol 69 (8) ◽

pp. 3492-3500 ◽

Cited By ~ 19

Author(s):

Tatsushi Toyooka ◽

Yuko Ibuki

Keyword(s):

Histone Deacetylase ◽

Nucleotide Excision Repair ◽

Sodium Butyrate ◽

Histone Deacetylase Inhibitor ◽

Excision Repair ◽

Cell Killing ◽

Killing Effect ◽

Deacetylase Inhibitor ◽

Nucleotide Excision ◽

Cell Killing Effect

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Epigenetic therapy using the histone deacetylase inhibitor for increasing therapeutic gain in oral cancer: prevention of radiation-induced oral mucositis and inhibition of chemical-induced oral carcinogenesis

Carcinogenesis ◽

10.1093/carcin/bgp079 ◽

2009 ◽

Vol 30 (8) ◽

pp. 1387-1397 ◽

Cited By ~ 32

Author(s):

Y.-L. Chung ◽

M.-Y. Lee ◽

N. N.M. Pui

Keyword(s):

Oral Cancer ◽

Cancer Prevention ◽

Histone Deacetylase ◽

Oral Mucositis ◽

Histone Deacetylase Inhibitor ◽

Epigenetic Therapy ◽

Oral Carcinogenesis ◽

Deacetylase Inhibitor ◽

Therapeutic Gain ◽

Radiation Induced

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Novel Three-Pronged Strategy to Enhance Cancer Cell Killing in Glioblastoma Cell Lines: Histone Deacetylase Inhibitor, Chemotherapy, and Oncolytic Adenovirus dl520

Human Gene Therapy ◽

10.1089/hum.2006.17.55 ◽

2006 ◽

Vol 17 (1) ◽

pp. 55-70 ◽

Cited By ~ 28

Author(s):

Alexa Bieler ◽

Klaus Mantwill ◽

Tanja Dravits ◽

Alexandra Bernshausen ◽

Gabriel Glockzin ◽

...

Keyword(s):

Histone Deacetylase ◽

Cell Lines ◽

Cancer Cell ◽

Histone Deacetylase Inhibitor ◽

Cell Killing ◽

Oncolytic Adenovirus ◽

Glioblastoma Cell ◽

Deacetylase Inhibitor ◽

Glioblastoma Cell Lines

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Novel Three-Pronged Strategy to Enhance Cancer Cell Killing in Glioblastoma Cell Lines: Histone Deacetylase Inhibitor, Chemotherapy, and Oncolytic Adenovirus dl520

Human Gene Therapy ◽

10.1089/hum.2005.17.ft-161 ◽

2005 ◽

Vol 0 (0) ◽

pp. 051221055602001

Author(s):

Alexa Bieler ◽

Klaus Mantwill ◽

Tanja Dravits ◽

Alexandra Bernshausen ◽

Gabriel Glockzin ◽

...

Keyword(s):

Histone Deacetylase ◽

Cell Lines ◽

Cancer Cell ◽

Histone Deacetylase Inhibitor ◽

Cell Killing ◽

Oncolytic Adenovirus ◽

Glioblastoma Cell ◽

Deacetylase Inhibitor ◽

Glioblastoma Cell Lines

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Modulation of chromatin conformation by the histone deacetylase inhibitor trichostatin A promotes the removal of radiation-induced lesions in ataxia telangiectasia cell lines

Mutation Research/Genetic Toxicology and Environmental Mutagenesis ◽

10.1016/j.mrgentox.2018.06.016 ◽

2018 ◽

Vol 836 ◽

pp. 109-116 ◽

Cited By ~ 1

Author(s):

Alessandra Egidi ◽

Silvia Filippi ◽

Federico Manganello ◽

Wilner Lopez-Martinez ◽

Roberta Meschini

Keyword(s):

Histone Deacetylase ◽

Cell Lines ◽

Ataxia Telangiectasia ◽

Histone Deacetylase Inhibitor ◽

Trichostatin A ◽

Chromatin Conformation ◽

Deacetylase Inhibitor ◽

Histone Deacetylase Inhibitor Trichostatin ◽

Radiation Induced

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Combining Histone Deacetylase Inhibitor Vorinostat with Aurora Kinase Inhibitors Enhances Lymphoma Cell Killing with Repression of c-Myc, hTERT, and microRNA Levels

Cancer Research ◽

10.1158/0008-5472.can-10-2259 ◽

2011 ◽

Vol 71 (11) ◽

pp. 3912-3920 ◽

Cited By ~ 76

Author(s):

Leo Kretzner ◽

Anna Scuto ◽

Pamela M. Dino ◽

Claudia M. Kowolik ◽

Jun Wu ◽

...

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Kinase Inhibitors ◽

Aurora Kinase ◽

Cell Killing ◽

Lymphoma Cell ◽

Aurora Kinase Inhibitors ◽

Deacetylase Inhibitor

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Low-dose spiruchostatin-B, a potent histone deacetylase inhibitor enhances radiation-induced apoptosis in human lymphoma U937 cells via modulation of redox signaling

Free Radical Research ◽

10.3109/10715762.2015.1115029 ◽

2016 ◽

Vol 50 (6) ◽

pp. 596-610 ◽

Cited By ~ 1

Author(s):

Mati Ur Rehman ◽

Paras Jawaid ◽

Qing Li Zhao ◽

Peng Li ◽

Koichi Narita ◽

...

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Low Dose ◽

Redox Signaling ◽

U937 Cells ◽

Deacetylase Inhibitor ◽

Human Lymphoma ◽

Radiation Induced ◽

Induced Apoptosis

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147: Low Concentration of a Histone Deacetylase Inhibitor, Depsipeptide (FK228), Enhances the Effect of Gemcitabine and Docetaxel in Hormone Refractory Prostate Cancer Cells

The Journal of Urology ◽

10.1016/s0022-5347(18)30412-9 ◽

2007 ◽

Vol 177 (4S) ◽

pp. 50-51

Author(s):

Masatoshi Kanzaki ◽

Hideaki Kakinuma ◽

Teruaki Kumazawa ◽

Takamitsu Inoue ◽

Mitsuru Saito ◽

...

Keyword(s):

Prostate Cancer ◽

Cancer Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Hormone Refractory Prostate Cancer ◽

Prostate Cancer Cells ◽

Low Concentration ◽

Deacetylase Inhibitor ◽

Hormone Refractory

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Structure-activity investigations of Santacruzamate A, a potent histone deacetylase inhibitor isolated from a Panamanian cyanobacterium

Planta Medica ◽

10.1055/s-0032-1320383 ◽

2012 ◽

Vol 78 (11) ◽

Author(s):

CM Pavlik ◽

MJ Balunas

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Structure Activity ◽

Deacetylase Inhibitor

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